RBRC09759, B6.129P2-Chd8<tm2.1Kei>

RBRC No. RBRC09759
Type Targeted MutationCartagena
Species Mus musculus
Strain name B6.129P2-Chd8<tm2.1Kei>
Former Common name Chd8L KO
H-2 Haplotype No Data
ES cell line E14 [129P2/OlaHsd]
Background strain C57BL/6JJcl
Appearance
1 Appearance No Data
Genotype No Data
Strain development Deposited by Keiichi Nakayama, Medical Institute of Bioregulation, Kyusyu University in 2016. E14(129P2/OlaHsd) ES cell line was used. C57BL/6 congenic strain.
Strain description Chd8l (chromodomain helicase DNA binding protein 8 long isoform) knockout mice. Homozygous mutants are lethal. A pair of loxP sites with a neo gene cassette flanking exons 11 to 13, and then these exons were deleted by Cre expression in ES cells. Mouse strain carrying deletion of both long isoform (Chd8l) and short isoform (Chd8s) is available as RBRC09758.
Health Report
Gene Details
Promoter No Data
1 Symbol Chd8
Symbol name chromodomain helicase DNA binding protein 8
Chromosome 14
Common name No Data
Symbol description No Data
2 Symbol loxP
Symbol name phage P1 loxP
Chromosome 14
Common name No Data
Symbol description No Data
References No Data

Research applications Cre/loxP system,
Mouse Models for Human Disease
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form.
The RECIPIENT agrees to use this BIOLOGICAL RESOURCE as a collaboration with the DEPOSITOR.
Additional information
1 Mouse of the Month Nov 2018
2 Genotyping protocol <PCR>
Depositor Nakayama, Keiichi (Medical institute of bioregulation, Kyushu University) Nakayama, Keiichi
Strain Status /
Availability
(Expected delivery)


Sperm
Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months