RBRC10238, B6;Cg-Tg(Cryd1/Cryaa-Sfrp2)1Jmca

RBRC No. RBRC10238
Type Targeted Mutation CongenicCartagena
Species Mus musculus
Strain name B6;Cg-Tg(Cryd1/Cryaa-Sfrp2)1Jmca
Former Common name Sfrp2 lens (M2)
H-2 Haplotype No Data
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain development Transgenic construct was injected into BCBF1 (C57/BL6xCBA) embryos.
Generated by John McAvoy laboratory in the University of Sydney.
After backcrossing to C57/BL6 line for a few generations, the line has been maintained as inbred.
Small lens formation. Cataract development.Mice can be maintained as heterozygous or homozygous.
Strain description Transgenic mouse line with Sfrp2 (secreted frizzled related protein-2) overexpression in lens.
Health Report
Gene Details
Promoter No Data
1 Symbol GH
Symbol name Human growth hormone poly A
Chromosome UN
Common name No Data
Symbol description No Data
Promoter Chicken delta 1-crystallin (ASL1) enhancer and promoter, Mouse alpha A-crystallin (Cryaa) promoter, Rabbit beta-globin intron
2 Symbol Sfrp2
Symbol name secreted frizzled-related protein 2
Chromosome UN
Common name No Data
Symbol description No Data
References No Data

Research applications Developmental Biology Research
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
Development Biology, 324, 161-176 (2008).
In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
For use of the BIOLOGICAL RESOURCE by a for-profit organization, the RECIPIENT must reach agreement on terms and conditions of use of it with DEPOSITOR and must obtain a prior written consent from the DEPOSITOR. RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE.
Additional information
1 No Data
Depositor Sugiyama, Yuki (Okinawa Institute of Science and Technology Graduate University) Sugiyama, Yuki
Strain Status /
Availability
(Expected delivery)


Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

Sperm
Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months

Live
Live mouse :