Strain Data Sheet

RBRC10448

Strain Information

Image
BRC No.RBRC10448
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6.129-Apba1<tm1Amor>/Tsuz
Former Common nameX11/mint 1 -KO mice
H-2 Haplotype
ES Cell lineCCE28 [129/Sv]
Background strain
Appearance
Strain developmentDeposited by Toshiharu Suzuki, Hokkaido University in 2018. This mutated allele was originally generated by Otsuka Pharmaceutical Co., Ltd. using ES cells derived from 129/SV. This strain was further backcrossed to C57BL/6J for 10 generations by the depositor.
Strain descriptionApba1 (amyloid beta (A4) precursor protein binding, family A, member 1; X11/mint 1) knockout mice. Homozygous mutants are fertile, but their littermate size is small (3 to 5 pups per litter). Heterozygous mice are used for breeding.
Colony maintenance
ReferencesNeurosci. Res., 43, 251-257 (2002). 12103443
J. Biol. Chem., 283, 35763-35771 (2008). 18845544

Health Report

Examination Date / Room / Rack

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Apba1amyloid beta (A4) precursor protein binding, family A, member 119Apba1<tm1Amor>targeted mutation 1, Atsushi Mori

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
neoneomycin resistance gene (E. coli)19herpes simplex virus thymidine kinase promoter (HSV tk promoter)

Ordering Information

Donor DNAherpes simplex virus thymidine kinase prpmoter (MC1 prpmoter), E. coli neo, polyA, mouse Apba1 genomic DNA
Research application
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Neurosci. Res., 43, 251-257 (2002). J. Biol. Chem. 283, 35763-35771 (2008). The availability of the BIOLOGICAL RESOURCE is limited to a RECIPIENT of a not-for profit institution for a not-for-profit research.
DepositorToshiharu Suzuki (Hokkaido University)
Strain Statusan icon for Frozen embryosFrozen embryos
an icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved sperm (2 to 4 months)
Cryopreserved sperm (within 1 month)
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  3. Acceptance of responsibility for living modified organism (Japanese / English)

Genotyping protocol -PCR-

BRC mice in Publications

No Data