RBRC10757, B6.129-Mab21l2<tm1Nao>

RBRC No. RBRC10757
Type Targeted MutationCartagena
Species Mus musculus
Strain name B6.129-Mab21l2<tm1Nao>
Former Common name C57BL/6(Mab21l2tm1Nao), Mab21l2tm1Nao
H-2 Haplotype No Data
ES cell line R1 [(129X1/SvJ x 129S1/Sv)F1-Kitl<+>]
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain development lethality throughout fetal growth and development, complete penetrance
abnormal heart position or orientation
abnormal retina morphology
abnormal ventral body wall morphology
Strain description This gene is similar to the MAB-21 cell fate-determining gene found in C. elegans. It is required for several aspects of embryonic development including normal development of the eye, heart and body wall. Mutation details: The entire gene coding region was replaced with a neomycin resistance cassette via homologous recombination. Absence of gene expression in homozygous mutants was confirmed by whole mount in situ hybridization analysis of E10.5 homozygous mutant embryos.
Health Report No Data
Gene Details
Promoter No Data
1 Symbol No Data
Symbol name SV40 polyA
Chromosome 3
Common name No Data
Symbol description No Data
2 Symbol Mab21l2
Symbol name mab-21-like 2
Chromosome 3
Common name No Data
Symbol description No Data
Promoter herpes simplex virus thymidine kinase promoter (HSV tk promoter)
3 Symbol neo
Symbol name neomycin resistance gene (E. coli)
Chromosome 3
Common name No Data
Symbol description No Data
References No Data

Research applications No Data
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form.
Additional information
1 No Data
Depositor Takahashi, Naoki (The University of Tokyo) Takahashi, Naoki
Strain Status /
Availability
(Expected delivery)


Preparing for distribution
Preparing for distribution
(Please note that it may take more than 6 months to make arrangements to distribute.)

Sperm
Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months

Live
Live mouse :