Strain Information | |
---|---|
Image | |
BRC No. | RBRC10935 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | B6N.129-Brsk1<tm1Jrs>/Kcn |
Former Common name | SAD-B KO |
H-2 Haplotype | |
ES Cell line | R1 [(129X1/SvJ x 129S1/Sv)F1-Kitl<+>] |
Background strain | |
Appearance | |
Strain development | Deeposited by Keiko Nakanishi, Aichi Developmental Disability Center in 2019. |
Strain description | Brsk1 knockout mice. Exon1 of the Brsk1 gene was replaced with a neo cassette. B6N congenic strain. |
Colony maintenance | |
References | Science. 2005 DOI:10.1126/science.1107403 15705853 Cereb Cortex. 2018 DOI:10.1093/cercor/bhy253 30307479 |
Health Report | |
---|---|
Examination Date / Room / Rack |
Gene | |
---|---|
Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP7loxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP7loxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter neoneomycin resistance gene (E. coli)7mouse phosphoglycerate kinase promoter (PGK promoter) |
Ordering Information | |
---|---|
Donor DNA | phage P1 loxP sites, mouse PGK promoter, E. coli Neomycin resistant gene, mouse Brsk1 genomic DNA |
Research application | Cre/loxP system Neurobiology Research |
Specific Term and Conditions | Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Science. 2005 DOI:10.1126/science.1107403, Cereb Cortex. 2018 DOI:10.1093/cercor/bhy253 |
Depositor | Keiko Nakanishi (Aichi Developmental Disability Center Central Hospital) |
Strain Status | Frozen sperm |
Strain Availability | Recovered litters from cryopreserved sperm (2 to 4 months) Cryopreserved sperm (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
---|
No Data |