RBRC-KIT0028, KITOX-BM15-Mu

RBRC No. RBRC-KIT0028
Type Chemically-induced Mutation
Species Mus musculus
Strain name KITOX-BM15-Mu
Former Common name No Data
H-2 Haplotype No Data
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain development Developed by Chang-Woo Song and Jae-Woo Cho, Korea Institute of Toxicology in Korea Research Institute of Chemical Technology. Mutant mice were crossed to BALB/c.
Strain description Homozygous mutant mice resemble hairless rhino mice in which no hair regeneration occurs and skin tissue is extensively folded. A mutation in the human homolog of Hr (HR; OMIM602302) , are known to cause congenital hairless disease, alopecia universalis congenita (OMIM602302). The Depositors are welcome to collaborate further detailed analyses on this mutant mouse. Series of other ENU-mutant mice with interesting phenotypes have also been deposited to RIKEN BRC.
Colony maintenance Heterozygote (male) x Homozygote (female) Homozygous mutant females have nurturing young, possibly as a result of defects in lactation.
Health Report
Gene Details
Promoter No Data
1 Symbol Hr
Symbol name hairless
Chromosome 14
Common name Hr
Symbol description No Data
References No Data

Research applications No Data
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR.
In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
Prior to filing for a patent, or intellectual property or other rights based on results of research using the BIOLOGICAL RESOURCE, the RECIPIENT shall acquire the consent from the DEPOSITOR for such application. Use of the BIOLOGICAL RESOURCE shall be limited to a collaborative research. And Use of the BIOLOGICAL RESOURCE shall require co-authorship of the DEPOSITOR for TWO years after deposition of the BIOLOGICAL RESOURCE to the RIKEN BRC or for the first publication if no publication is made within the TWO years.
Additional information
1 Mouse of the Month Apr 2005
2 Korea Institute of Toxicology HP
Depositor Song, Chang-Woo (Korea Institute of Toxicology) Song, Chang-Woo
Strain Status /
Availability
(Expected delivery)


Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months