Strain Data Sheet

RBRC02431

Strain Information

Image
BRC No.RBRC02431
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6.129-Drd2<tm1Mok> Drd3<tm1Mok> Drd4<tm1Mok>
Former Common nameD2R D3R D4R multiple KO, B6-D2R/D3R/D4R KO
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain developmentDeveloped by Motoya Katsuki, National Institutes of Natural Sciences.
Strain descriptionD2R (Drd2), D3R (Drd3) and D4R (Drd4) triple knockout mice.
Colony maintenance
ReferencesGenes Cells. 1(2):253-68 (1996). 9140068

Health Report

Examination Date / Room / Rack2023/02/27Room:4-CRack:H
2022/11/29Room:4-CRack:H
2022/08/29Room:4-CRack:H
2022/05/31Room:4-CRack:H

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Drd3dopamine receptor 316Drd3<tm1Mok>targeted mutation 1, Motoya KatsukiD3 receptor, D3R

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
EcogptE.coli xanthine phosphoribosyltransferase16Ecogptmouse phosphoglycerate kinase promoter (PGK promoter)

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
neoneomycin resistance gene (E. coli)16herpes simplex virus thymidine kinase promoter (HSV tk promoter)

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Drd4dopamine receptor 47Drd4<tm1Mok>targeted mutation 1, Motoya KatsukiD4R, Drd-4

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
EcogptE.coli xanthine phosphoribosyltransferase7Ecogptmouse phosphoglycerate kinase promoter (PGK promoter)

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
neoneomycin resistance gene (E. coli)7mouse RNA polymerase II large subunit promoter

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Drd2dopamine receptor D29Drd2<tm1Mok>targeted mutation 1, Motoya Katsuki

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
neoneomycin resistance gene (E. coli)9herpes simplex virus thymidine kinase promoter (HSV tk promoter)

Ordering Information

Donor DNAherpes simplex virus thymidine kinase promoter (HSV tk promoter), E. coli neo, mouse phosphoglycerate kinase promoter (PGK promoter), E. coli xanthine phosphoribosyltransferase (Ecogpt), mouse Dopamine receptor 2 genomic DNA, mouse Dopamine receptor 3 genomic DNA, mouse Dopamine receptor 4 genomic DNA
Research applicationNeurobiology Research
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Genes Cells, 1, 253-268 (1996).In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to Dr. Motoya Katsuki is requested. The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE.
DepositorToshikuni Sasaoka (Niigata University)
Strain Statusan icon for Frozen embryosFrozen embryos
an icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
Cryopreserved sperm (within 1 month)
Cryopreserved embryos (within 1 month)
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  3. Acceptance of responsibility for living modified organism (Japanese / English)

Genotyping protocol -PCR-

BRC mice in Publications

No Data