Strain Information | |
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Image | |
BRC No. | RBRC02485 |
Type | Targeted Mutation and Transgene |
Species | Mus musculus |
Strain name | B6.Cg-Hras1<tm1Mok> Nras<tm1Mok> Kras<tm1Mok> Tg(HRAS/floxed)1Mok |
Former Common name | H-ras, N-ras, K-ras triple KO, L-Tg, B6-Hras KO/Nras KO/Kras KO/HRASfloxed Tg |
H-2 Haplotype | |
ES Cell line | CCE/EK.CCE [129S/SvEv-Gpi1<c>] |
Background strain | |
Appearance | |
Strain development | Developed by Motoya Katsuki, National Institutes of Natural Sciences. |
Strain description | Hras knockout, Nras knockout, Kras knockout and Lras transgenic multiple mutant mice. |
Colony maintenance | |
References | Oncogene, 19, 2951-2956 (2000). 10871846 EMBO J. 21(5):1021-30 (2002). 11867530 Oncogene, 15, 1151-1159 (1997). 9294608 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter neoneomycin resistance gene (E. coli)3neo; neomycin;herpes simplex virus thymidine kinase promoter (HSV tk promoter) Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Krasv-Ki-ras2 Kirsten rat sarcome viral oncogene homolog6Kras<tm1Mok>targeted mutation 1, Motoya Katsuki Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter neoneomycin resistance gene (E. coli)7 Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter HRASHarvey rat sarcoma virus oncogene (human)UNHRAS Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxPUNloxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxPUNloxP |
Ordering Information | |
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Donor DNA | E. coli neo, mouse N-ras genomic DNA, mouse H-ras genomic DNA, mouse K-ras genomic DNA, human H-ras genomic DNA |
Research application | |
Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Oncogene, 19, 2951-2956 (2000). EMBO J., 21, 1021-1030 (2000). Oncogene, 15, 1151-1159 (1997).In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to Dr. Motoya Katsuki is requested. The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE. |
Depositor | Toshikuni Sasaoka (Niigata University) |
Strain Status | Frozen embryos |
Strain Availability | Recovery and QC required prior to distribution |
Additional Info. | Necessary documents for ordering: |
BRC mice in Publications |
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No Data |