Strain Information | |
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Image | |
BRC No. | RBRC03506 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | B6.Cg-Tead4<tm1Hssk>/Rbrc |
Former Common name | Tead4(IRES-lacZ) (Acc.No. CDB0409K) |
H-2 Haplotype | |
ES Cell line | TT2 [(C57BL/6NCrlj x CBA/JNCrlj)F1] |
Background strain | |
Appearance | |
Strain development | Developed by Hiroshi Sasaki, RIKEN Center for Developmental Biology. |
Strain description | Tead4 knockout mice. Homozygous mutant mice are embryonic lethal. No embryos are recovered at post-impalntation stages. Exon 2 of Tead4 gene was replaced by the insertion of a loxP-PGK-neo-polyA-loxP cassette and a IRES-beta-geo-polyA cassette. |
Colony maintenance | |
References | Mech. Dev., 125, 270-283 (2008). 18083014 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info |
Ordering Information | |
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Donor DNA | LacZ,Neo:大腸菌由来, lox71,loxP:P1ファージ由来, frt:酵母菌由来, PGKプロモーター,PGK3’end:マウス由来, rabbit beta-globin 3’end:ウサギ由来, IRES:ピコルナウイルス科ECMV由来 |
Research application | |
Specific Term and Conditions | (1) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the Accession No. (CDB0409K) (https://large.riken.jp/distribution/mutant-list.html) and the BIOLOGICAL RESOURCE is requested. (2) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the literature designed by the DEPOSITOR is requested. (Mech Dev. 2008 125(3-4):270-83.) (3) Please inform the DEPOSITOR (mutant.bdr@riken.jp) about the paper when published. |
Depositor | RIKEN CDB (RIKEN CDB) |
Strain Status | Frozen embryos Frozen sperm |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved sperm (within 1 month) Cryopreserved embryos (within 1 month) |
Additional Info. | Necessary documents for ordering: |
BRC mice in Publications |
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No Data |