Strain Information | |
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Image | |
BRC No. | RBRC03712 |
Type | Gene Trap |
Species | Mus musculus |
Strain name | B6;129P2-Dgcr8<Gt(XG058)Byg> |
Former Common name | DGCR8KO/XG058 |
H-2 Haplotype | |
ES Cell line | |
Background strain | |
Appearance | |
Strain development | Developed by Dr. Takashi Iwamoto, Chubu University in 2007. |
Strain description | DGCR8 is a key molecule of biogenesis of microRNA. DGCR8-/- mice are embryonic lethal and DGCR8-/+ mice look healthy but could be models of human 22q11.2 deletion syndrome including schizophrenia. |
Colony maintenance | |
References | Nat. Genet., 40, 751-760 (2008). 18469815 Nat. Genet., 39, 380-385 (2007). 17259983 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info |
Ordering Information | |
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Donor DNA | E coli Neomycin resistance gene, E coli beta-galactosidase, mouse EN2 gene intron, mouse Splice acceptor of EN2 gene exon2 |
Research application | |
Specific Term and Conditions | The RECIPIENT agrees to use the BIOLOGICAL RESOURCE only for publication of research papers. The RECIPIENT of BIOLOGICAL RESOURCE must obtain a prior written consent on use of it from the DEPOSITOR/DEVELOPER. All data got with this BIOLOGICAL RESOURCE must be published as a joint result with the DEPOSITOR. |
Depositor | Takashi Iwamoto (Chubu University) |
Strain Status | Frozen embryos Frozen sperm |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved sperm (within 1 month) Cryopreserved embryos (within 1 month) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |