Strain Data Sheet

RBRC04922

Strain Information

Image
BRC No.RBRC04922
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6.129S7-Ifngr1<tm1Agt>
Former Common name
H-2 Haplotype
ES Cell lineAB1 [129S7/SvEvBrd-Hprt<+>]
Background strain
Appearance
Strain developmentDeveloped by Michel Aguet, Institute of Molecular Biology I, University of Zurich in 1993. C57BL/6 background. Maintained by The Institute of Medical Science, The University of Tokyo.
Strain descriptionIFN gamma 1 knockout mice. Homozygous mutant mice show increased susceptibility to infection.
Colony maintenance
ReferencesScience, 259, 1742-1745 (1993). 8456301

Health Report

Examination Date / Room / Rack

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Ifngr1interferon gamma receptor 110Ifngr1<tm1Agt>targeted mutation 1, Michel Aguet

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
neoneomycin resistance gene (E. coli)10neo; neomycin;herpes simplex virus thymidine kinase promoter (HSV tk promoter)

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
SV40 PolyA signal10

Ordering Information

Donor DNAherpes simplex virus thymidine kinase promoter (HSV tk promoter), E. coli Neomycin resistance gene, SV40 PolyA signal, mouse Ifngr1 genomic DNA
Research applicationImmunology and Inflammation Research
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Science, 259, 1742-1745 (1993).In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
DepositorYoichiro Iwakura (The University of Tokyo)
Strain Statusan icon for Frozen embryosFrozen embryos
an icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
Cryopreserved sperm (within 1 month)
Cryopreserved embryos (within 1 month)
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  3. Acceptance of responsibility for living modified organism (Japanese / English)

Genotyping protocol -PCR-

BRC mice in Publications

No Data