Strain Data Sheet

RBRC06178

Strain Information

Image
BRC No.RBRC06178
TypeSpontaneous Mutation
SpeciesMus musculus
Strain nameB6;KOR1-Pitx3<+/->
Former Common nameB6-Pitx3
H-2 Haplotype
ES Cell line
Background strain
Appearance
Strain developmentDeveloped by Yoshibumi Mastushima, Saitama Cancer Center, Research Institute for Clinical Oncology.
Strain descriptionPitx3 gene mutant mice. Spontaneous mutation arose in KOR1 mouse colony derived from Japanese wild mice (Mus musculus molossinus). Homozygous mutant mice exhibit microphthalmia. KOR1 original line (RBRC06180), C57BL/6 background (semicongenic line) (RBRC06178), BALB/c background (RBRC06179).
Colony maintenanceHomozygote x Homozygote [or Crossing to C57BL/6NCrSlc (Cross-Intercross Breeding)]
ReferencesPLoS ONE 9(10): e111432 (2014). 25347445
J. Hered., 59(2):147-50 (1968). 4970465
Exp. Anim., 61(1) 25-33 (2012). 22293669

Health Report

Examination Date / Room / Rack

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Pitx3paired-like homeodomain transcription factor 319Pitx3

Ordering Information

Donor DNA
Research applicationDevelopmental Biology Research
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Exp. Anim., 61(1) 25-33 (2012). PLoS ONE 9(10): e111432 (2014).
DepositorYoshibumi Matsushima (Saitama Cancer Center)
Strain Statusan icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved sperm (2 to 4 months)
Cryopreserved sperm (within 1 month)
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)

BRC mice in Publications

No Data