Strain Data Sheet

RBRC06225

Strain Information

Image
BRC No.RBRC06225
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameB6;129-Slc39a7<tm1.1Tfk>
Former Common nameZIP7 KO, B6-Slc39a7 floxed, B6;129-Slc39a7<tm1>
H-2 Haplotype
ES Cell lineR1 [(129X1/SvJ x 129S1/Sv)F1-Kitl<+>]
Background strain
Appearance
Strain developmentDeveloped by Toshiyuki Fukuda, RIKEN Center for Allergy and Immunology in 2013. R1 ES cells derived from (129X1/SvJ x 129S1/Sv)F1-Kitl<+> were used for the generation of floxed mice. The mutant mice were crossed to C57BL/6J over 9 times.
Strain descriptionZip7 (Slc39a7) gene floxed mice. Exons 5 and 6 were flanked by loxP sites.
Colony maintenanceHomozygote x Homozygote [or Crossing to C57BL/6JJcl]
ReferencesPLOS Genetics 12(10): e1006349 (2016). 27736879
J. Invest Dermatol., 137(8), 1682-1691(2017). 28545780

Health Report

Examination Date / Room / Rack

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Slc39a7solute carrier family 39 (zinc transporter), member 717Slc39a7<tm1.1Tfk>targeted mutation 1.1, Toshiyuki Fukada

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
loxPphage P1 loxP17loxP

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
loxPphage P1 loxP17loxP

Ordering Information

Donor DNAEnterobacteria phage P1 loxP sites, mouse Slc39a13 genomic DNA
Research applicationCre/loxP system
Developmental Biology Research
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. PLOS Genetics 12(10): e1006349, (2016).Prior to requesting the BIOLOGICAL RESOURCE, the Recipient shall contact with the Developer scientist (Dr. Toshiyuki Fukada, email: fukada@ph.bunri-u.ac.jp) and obtain the use permission.
DepositorDrs. Shigeo Koyasu and Toshiyuki Fukada (RIKEN)
Strain Statusan icon for Frozen embryosFrozen embryos
an icon for Frozen spermFrozen sperm
Strain AvailabilityRecovered litters from cryopreserved embryos (2 to 4 months)
Cryopreserved sperm (within 1 month)
Additional Info.Genotyping protocol -PCR-
Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  3. Acceptance of responsibility for living modified organism (Japanese / English)

BRC mice in Publications

No Data