Strain Information | |
---|---|
Image | |
BRC No. | RBRC06225 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | B6;129-Slc39a7<tm1.1Tfk> |
Former Common name | ZIP7 KO, B6-Slc39a7 floxed, B6;129-Slc39a7<tm1> |
H-2 Haplotype | |
ES Cell line | R1 [(129X1/SvJ x 129S1/Sv)F1-Kitl<+>] |
Background strain | |
Appearance | |
Strain development | Developed by Toshiyuki Fukuda, RIKEN Center for Allergy and Immunology in 2013. R1 ES cells derived from (129X1/SvJ x 129S1/Sv)F1-Kitl<+> were used for the generation of floxed mice. The mutant mice were crossed to C57BL/6J over 9 times. |
Strain description | Zip7 (Slc39a7) gene floxed mice. Exons 5 and 6 were flanked by loxP sites. |
Colony maintenance | Homozygote x Homozygote [or Crossing to C57BL/6JJcl] |
References | PLOS Genetics 12(10): e1006349 (2016). 27736879 J. Invest Dermatol., 137(8), 1682-1691(2017). 28545780 |
Health Report | |
---|---|
Examination Date / Room / Rack |
Gene | |
---|---|
Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Slc39a7solute carrier family 39 (zinc transporter), member 717Slc39a7<tm1.1Tfk>targeted mutation 1.1, Toshiyuki Fukada Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP17loxP Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP17loxP |
Ordering Information | |
---|---|
Donor DNA | Enterobacteria phage P1 loxP sites, mouse Slc39a13 genomic DNA |
Research application | Cre/loxP system Developmental Biology Research |
Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. PLOS Genetics 12(10): e1006349, (2016).Prior to requesting the BIOLOGICAL RESOURCE, the Recipient shall contact with the Developer scientist (Dr. Toshiyuki Fukada, email: fukada@ph.bunri-u.ac.jp) and obtain the use permission. |
Depositor | Drs. Shigeo Koyasu and Toshiyuki Fukada (RIKEN) |
Strain Status | Frozen embryos Frozen sperm |
Strain Availability | Recovered litters from cryopreserved embryos (2 to 4 months) Cryopreserved sperm (within 1 month) |
Additional Info. | Genotyping protocol -PCR- Necessary documents for ordering: |
BRC mice in Publications |
---|
No Data |