Strain Information | |
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Image | |
BRC No. | RBRC06229 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | C.B6-Bcl11b<tm2.1Jpk> |
Former Common name | BALB-Bcl11b floxed |
H-2 Haplotype | |
ES Cell line | RENKA [C57BL/6NCrlCrlj] |
Background strain | BALB/cAJcl |
Appearance | |
Strain development | Developed by Ryo Kominami, Graduate School of Medical and Dental Science and Kenji Sakimura, Brain Research Institute, Niigata University. RENKA ES cells derived from C57BL/6NCrlCrlj were used for the generation of floxed mice. Neo cassette was removed by crossing with B6-CAG-FLPe mice (RBRC01824). C57BL/6 background (RBRC06226), BALB/c background (RBRC06229). |
Strain description | Bcl11b floxed mice. Exon 2 was flanked by loxP sites. C57BL/6 background (RBRC06226), BALB/c background (RBRC06229). |
Colony maintenance | Homozygote x Homozygote [or Crossing to BALB/cAJcl] |
References | Cancer Sci., 104. 1009-1016 (2013). 23663453 |
Health Report | |
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Examination Date / Room / Rack |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Frtyeast FRT (flippase recombination target) site12Frt Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP12loxP |
Ordering Information | |
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Donor DNA | P1 phage loxP, Saccharomyces cerevisiae FRT, mouse Bcl11b genomic DNA |
Research application | Cancer Research Cre/loxP system FLP/frt system |
Specific Term and Conditions | Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. |
Depositor | Ryo Kominami (Niigata University) |
Strain Status | Frozen embryos |
Strain Availability | Recovery and QC required prior to distribution |
Additional Info. | Necessary documents for ordering: |
BRC mice in Publications |
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No Data |