Strain Information | |
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Image | |
BRC No. | RBRC10172 |
Type | Targeted Mutation Congenic |
Species | Mus musculus |
Strain name | B6;Cg-Sftpc<tm1(cre/ERT2)Yasu> |
Former Common name | SftpC-CreERT2 |
H-2 Haplotype | |
ES Cell line | V6.5 [(C57BL/6J x 129S4/SvJae)F1] |
Background strain | |
Appearance | |
Strain development | Developed by Hirofumi Shibata and his colleagues in 2015, and deposited by Yasuhiro Yamada, Center for iPS Cell Research and Application, Kyoto University. V6.5 ES cells derived from (C57BL/6 x 129S4/SvJae)F1 were used. Mixed genetic background. |
Strain description | Knock-in mouse of CreERT2 at the translation initiation codon of the SftpC gene. Cre/loxP recombination can be induced by the administration of Tamoxifen. |
Colony maintenance | |
References |
Health Report | |
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Examination Date / Room / Rack | 2024/02/19Room:4-ARack:F 2023/11/20Room:4-ARack:F 2023/08/28Room:4-ARack:F 2023/08/21Room:4-ARack:F 2023/06/19Room:4-ARack:F 2023/05/22Room:4-ARack:F 2023/02/20Room:4-ARack:F 2022/11/21Room:4-ARack:F 2022/09/05Room:4-ARack:F 2022/08/22Room:4-ARack:F 2022/05/23Room:4-ARack:F |
Gene | |
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Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter BsdAspergillus terreus blasticidin resistance gene (Bsd)14Bsd Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter ERT2estrogen receptor (ER), human ER with the triple mutation G400V/M543A/L544A)14ERT2 Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter HBB2rabbit beta-globin polyA14HBB2 Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter crePhage P1 Cre recombinase14cre Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter SV40 PolyA signal14 |
Ordering Information | |
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Donor DNA | P1 Bacteriophage Cre recomibinase, human Estrogen receptor binding domain (ERT2)cDNA, Rabbit globin pA(CreERT2), D6 Bacteriophage rox site, mouse PGK promoter, Aspergillus terreus Blasticidin S deaminase gene (Bsd), Simian virus (SV40) pA, mouse Sftpc genomic DNA |
Research application | Cre/loxP system |
Specific Term and Conditions | The RECIPIENT agrees to use this BIOLOGICAL RESOURCE as a collaboration with the DEVELOPER. The BIOLOGICAL RESOURCE shall be used only for academic research purposes by a non-profit organization. |
Depositor | Yasuhiro Yamada (Kyoto University) |
Strain Status | Live mice Frozen embryos Frozen sperm |
Strain Availability | Cryopreserved sperm (within 1 month) Cryopreserved embryos (within 1 month) Live mouse (3 to 6 months) |
Additional Info. | Necessary documents for ordering:
Genotyping protocol -PCR- |
BRC mice in Publications |
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No Data |