Strain Information | |
---|---|
Image | |
BRC No. | RBRC10700 |
Type | Targeted Mutation |
Species | Mus musculus |
Strain name | C57BL/6-App<tm1(T668A)Tsuz> |
Former Common name | T668A delta neo (A/A) |
H-2 Haplotype | |
ES Cell line | MS12 [C57BL/6] |
Background strain | |
Appearance | |
Strain development | Deposited by Shigeyoshi Itohara, RIKEN Center for Brain Science. MS12 ES cells derived from C57BL/6NSlc were used. Mice were maintained by crossing to C57BL/6J. C57BL/6 genetic background. |
Strain description | A mutant strain in which a threonine to alanine mutation in codon 668 was introduced to the App gene. |
Colony maintenance | |
References | PLoS One, 1(1):e51 (2006). 17183681 |
Health Report | |
---|---|
Examination Date / Room / Rack |
Gene | |
---|---|
Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter loxPphage P1 loxP16loxP |
Ordering Information | |
---|---|
Donor DNA | マウス Thr668Ala, P1ファージ LoxP配列 |
Research application | Cre/loxP system Mouse Models for Human Disease |
Specific Term and Conditions | In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. PLoS One, 1(1):e51 (2006). |
Depositor | Shigeyoshi Itohara (RIKEN) |
Strain Status | Frozen embryos |
Strain Availability | Recovery and QC required prior to distribution |
Additional Info. | Necessary documents for ordering: |
BRC mice in Publications |
---|
No Data |