Strain Data Sheet

RBRC10700

Strain Information

Image
BRC No.RBRC10700
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameC57BL/6-App<tm1(T668A)Tsuz>
Former Common nameT668A delta neo (A/A)
H-2 Haplotype
ES Cell lineMS12 [C57BL/6]
Background strain
Appearance
Strain developmentDeposited by Shigeyoshi Itohara, RIKEN Center for Brain Science. MS12 ES cells derived from C57BL/6NSlc were used. Mice were maintained by crossing to C57BL/6J. C57BL/6 genetic background.
Strain descriptionA mutant strain in which a threonine to alanine mutation in codon 668 was introduced to the App gene.
Colony maintenance
ReferencesPLoS One, 1(1):e51 (2006). 17183681

Health Report

Examination Date / Room / Rack

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Appamyloid beta (A4) precursor protein16App<tm1(T668A)Tsuz>targeted mutation 1, Toshiharu Suzuki

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
loxPphage P1 loxP16loxP

Ordering Information

Donor DNAマウス Thr668Ala, P1ファージ LoxP配列
Research applicationCre/loxP system
Mouse Models for Human Disease
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. PLoS One, 1(1):e51 (2006).
DepositorShigeyoshi Itohara (RIKEN)
Strain Statusan icon for Frozen embryosFrozen embryos
Strain AvailabilityRecovery and QC required prior to distribution
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  3. Acceptance of responsibility for living modified organism (Japanese / English)

BRC mice in Publications

No Data