Strain Data Sheet

RBRC10701

Strain Information

Image
BRC No.RBRC10701
TypeTargeted MutationCartagena
SpeciesMus musculus
Strain nameC57BL/6-App<tm1.1(T668D)Ito>
Former Common nameT668D delta neo
H-2 Haplotype
ES Cell lineMS12 [C57BL/6]
Background strain
Appearance
Strain developmentDeposited by Shigeyoshi Itohara, RIKEN Center for Brain Science. MS12 ES cells derived from C57BL/6NSlc were used. Mice were maintained by crossing to C57BL/6J. C57BL/6 genetic background.
Strain descriptionA mutant strain in which a threonine to aspartic acid mutation in codon 668 was introduced to the App gene.
Colony maintenance
References

Health Report

Examination Date / Room / Rack

Gene

Gene info
Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
Appamyloid beta (A4) precursor protein16App<tm1.1(T668D)Ito>targeted mutation 1, Shigeyoshi Itohara

Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter
loxPphage P1 loxP16loxP

Ordering Information

Donor DNAマウス Thr668Asp in App gene, P1ファージ LoxP配列
Research applicationCre/loxP system
Mouse Models for Human Disease
Specific Term and ConditionsIn publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. (will be announced.)
DepositorShigeyoshi Itohara (RIKEN)
Strain Statusan icon for Frozen embryosFrozen embryos
Strain AvailabilityRecovery and QC required prior to distribution
Additional Info.Necessary documents for ordering:
  1. Order form (Japanese / English)
  2. Category I MTA: MTA for distribution with RIKEN BRC (Japanese / English)
  3. Acceptance of responsibility for living modified organism (Japanese / English)

BRC mice in Publications

No Data