Strain Data Sheet
RBRC10950
Strain Information | |
|---|---|
| Image | |
| BRC No. | RBRC10950 |
| Type | Transgene |
| Species | Mus musculus |
| Strain name | C57BL/6-Tg(CAG-Sphk1)H1Ytak |
| Former Common name | Sphk1 transgenic mice (Tg line: High) |
| H-2 Haplotype | |
| ES Cell line | |
| Background strain | |
| Appearance | |
| Strain development | Developed by Yo Takuwa, Kanazawa University in 2003. C57BL/6 genetic background. |
| Strain description | Transgenic mice expressing mouse Sphk1 gene cDNA under the control of CAG promoter. |
| Colony maintenance | |
| References | Cardiovasc. Res., 85(3):484-93 (2010). 19755413 Cardiovasc. Res., 78, 301-307 (2008). 18187460 Diabetes, 61, 3148-3155 (2012). 22961081 |
Health Report | |
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| Examination Date / Room / Rack | |
Gene | |
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| Gene info | Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter Sphk1sphingosine kinase 1UNSphk1CAG promoter (CMV-IE enhancer, chicken beta-actin promoter, rabbit beta-globin genomic DNA) Gene symbolGene nameChr.Allele symbolAllele nameCommon namesPromoter SV40 polyA signalUN |
Ordering Information | |
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| Donor DNA | Cytomegalovirus CMV-IE enhancer, Chicken beta-actin promoter, Rabbit beta-globin genomic DNA, Mouse Sphk1a gene cDNA, SV40 PolyA signal |
| Research application | |
| Specific Term and Conditions | Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Cardiovasc Res. 2010 Feb 1;85(3):484-93. doi: 10.1093/cvr/cvp312 |
| Depositor | Yoh Takuwa (Kanazawa University) |
| Strain Status |  Frozen embryos |
| Strain Availability |  Recovery and QC required prior to distribution |
| Additional Info. | Necessary documents for ordering: |
BRC mice in Publications |
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| No Data |