RBRC00428, Mol-KOR5/Stm

RBRC No. RBRC00428
Type Wild-derived Inbred wks
Species Mus musculus molossinus
Strain name Mol-KOR5/Stm
Former Common name M. m. molossinus Kor-5
H-2 Haplotype No Data
Background strain KOR5 [Mus musculus molossinus]
Appearance
1 Appearance white bellied agouti
Genotype No Data
Strain description No Data
Health Report
Gene Details
Promoter No Data
1 Symbol No Data
Symbol name No Data
Chromosome No Data
Common name No Data
Symbol description No Data
References

Research applications No Data
Specific Term and Conditions No specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.)
Additional information
1 Click Here for Mouse genomic DNA (RIKEN DNA Bank)
Depositor Matsushima, Yoshibumi (Saitama Cancer Center) Matsushima, Yoshibumi
Strain Status /
Availability
(Expected delivery)


Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months
BRC mice in Publications
Title Journal
(PMID)
Author
Endogenous gammaretrovirus acquisition in Mus musculus subspecies carrying functional variants of the XPR1 virus receptor. J Virol. (2013).(23824809)
Bamunusinghe D, Liu Q, Lu X, Oler A, Kozak CA.
Devising assisted reproductive technologies for wild-derived strains of mice: 37 strains from five subspecies of Mus musculus. PLoS One.9(12) e114305: e114305 (2014).(25470728)
Mochida K, Hasegawa A, Otaka N, Hama D, Furuya T, Yamaguchi M, Ichikawa E, Ijuin M, Taguma K, Hashimoto M, Takashima R, Kadota M, Hiraiwa N, Mekada K, Yoshiki A, Ogura A.

RBRC06178, B6;KOR1-Pitx3<+/->

RBRC No. RBRC06178
Type Spontaneous Mutation
Species Mus musculus
Strain name B6;KOR1-Pitx3<+/->
Former Common name B6-Pitx3
H-2 Haplotype No Data
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain development Developed by Yoshibumi Mastushima, Saitama Cancer Center, Research Institute for Clinical Oncology.
Strain description Pitx3 gene mutant mice. Spontaneous mutation arose in KOR1 mouse colony derived from Japanese wild mice (Mus musculus molossinus). Homozygous mutant mice exhibit microphthalmia. KOR1 original line (RBRC06180), C57BL/6 background (semicongenic line) (RBRC06178), BALB/c background (RBRC06179).
Colony maintenance Homozygote x Homozygote [or Crossing to C57BL/6NCrSlc (Cross-Intercross Breeding)]
Health Report
Gene Details
Promoter No Data
1 Symbol Pitx3
Symbol name paired-like homeodomain transcription factor 3
Chromosome 19
Common name No Data
Symbol description No Data
References

Research applications Developmental Biology Research
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
後日指定。(will be announced).
Additional information
1 No Data
Depositor Matsushima, Yoshibumi (Saitama Cancer Center) Matsushima, Yoshibumi
Strain Status /
Availability
(Expected delivery)


Sperm
Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months

RBRC00429, Mol-KOR7/Stm

RBRC No. RBRC00429
Type Wild-derived Inbred 4wks
Species Mus musculus molossinus
Strain name Mol-KOR7/Stm
Former Common name M. m. molossinus Kor-7
H-2 Haplotype No Data
Background strain KOR7 [Mus musculus molossinus]
Appearance
1 Appearance white-bellied agouti
Genotype Aw/Aw
Strain development The Mol-KOR7 strain was derived from Mus musculus molossinus mice trapped in Kouriyama, Fukushima, Japan in 1988 and maintained by Dr. Yoshifumi Matsushima, Saitama Cancer Center. Mice were deposited to the RIKEN BRC in July 2002.
Generation: F36(Stm)+F1F5(Rbrc)
Strain description The Mol-KOR7 strain was derived from Mus musculus molossinus mice trapped in Kouriyama, Fukushima, Japan in 1988 and maintained by Dr. Yoshifumi Matsushima, Saitama Cancer Center. Mice were deposited to the RIKEN BRC in July 2002. The genetical profile of this strain has not investigated yet.
Colony maintenance Sibling mating
Health Report
Gene Details
Promoter No Data
1 Symbol No Data
Symbol name No Data
Chromosome No Data
Common name No Data
Symbol description No Data
References

Research applications No Data
Specific Term and Conditions No specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.)
Additional information
1 Click Here for Mouse genomic DNA (RIKEN DNA Bank)
Depositor Matsushima, Yoshibumi (Saitama Cancer Center) Matsushima, Yoshibumi
Strain Status /
Availability
(Expected delivery)


Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months
BRC mice in Publications
Title Journal
(PMID)
Author
Endogenous gammaretrovirus acquisition in Mus musculus subspecies carrying functional variants of the XPR1 virus receptor. J Virol. (2013).(23824809)
Bamunusinghe D, Liu Q, Lu X, Oler A, Kozak CA.
Devising assisted reproductive technologies for wild-derived strains of mice: 37 strains from five subspecies of Mus musculus. PLoS One.9(12) e114305: e114305 (2014).(25470728)
Mochida K, Hasegawa A, Otaka N, Hama D, Furuya T, Yamaguchi M, Ichikawa E, Ijuin M, Taguma K, Hashimoto M, Takashima R, Kadota M, Hiraiwa N, Mekada K, Yoshiki A, Ogura A.

RBRC06179, C.KOR1-Pitx3<+/->

RBRC No. RBRC06179
Type Spontaneous Mutation
Species Mus musculus
Strain name C.KOR1-Pitx3<+/->
Former Common name BALB-Pitx3
H-2 Haplotype No Data
Background strain BALB/cCrSlc
Appearance
1 Appearance No Data
Genotype No Data
Strain development Developed by Yoshibumi Mastushima, Saitama Cancer Center, Research Institute for Clinical Oncology.
Strain description Pitx3 gene mutant mice. Spontaneous mutation arose in KOR1 mouse colony derived from Japanese wild mice (Mus musculus molossinus). Homozygous mutant mice exhibit microphthalmia. KOR1 original line (RBRC06180), C57BL/6 background (semicongenic line) (RBRC06178), BALB/c background (RBRC06179).
Colony maintenance Homozygote x Homozygote [or Crossing to BALB/cCrSlc (Cross-Intercross Breeding)]
Health Report
Gene Details
Promoter No Data
1 Symbol Pitx3
Symbol name paired-like homeodomain transcription factor 3
Chromosome 19
Common name No Data
Symbol description No Data
References

Research applications Developmental Biology Research
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
後日指定。(will be announced).
Additional information
1 No Data
Depositor Matsushima, Yoshibumi (Saitama Cancer Center) Matsushima, Yoshibumi
Strain Status /
Availability
(Expected delivery)


Sperm
Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months

RBRC00430, Mol-AIZ/Stm

RBRC No. RBRC00430
Type Wild-derived Inbred wks
Species Mus musculus molossinus
Strain name Mol-AIZ/Stm
Former Common name M.m.molossinus Aiz-2
H-2 Haplotype No Data
Background strain AIZ [Mus musculus molossinus]
Appearance
1 Appearance No Data
Genotype No Data
Strain description No Data
Health Report
Gene Details
Promoter No Data
1 Symbol No Data
Symbol name No Data
Chromosome No Data
Common name No Data
Symbol description No Data
References

Research applications No Data
Specific Term and Conditions No specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.)
Additional information
1 Click Here for Mouse genomic DNA (RIKEN DNA Bank)
Depositor Matsushima, Yoshibumi (Saitama Cancer Center) Matsushima, Yoshibumi
Strain Status /
Availability
(Expected delivery)


Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months
BRC mice in Publications
Title Journal
(PMID)
Author
Endogenous gammaretrovirus acquisition in Mus musculus subspecies carrying functional variants of the XPR1 virus receptor. J Virol. (2013).(23824809)
Bamunusinghe D, Liu Q, Lu X, Oler A, Kozak CA.
Devising assisted reproductive technologies for wild-derived strains of mice: 37 strains from five subspecies of Mus musculus. PLoS One.9(12) e114305: e114305 (2014).(25470728)
Mochida K, Hasegawa A, Otaka N, Hama D, Furuya T, Yamaguchi M, Ichikawa E, Ijuin M, Taguma K, Hashimoto M, Takashima R, Kadota M, Hiraiwa N, Mekada K, Yoshiki A, Ogura A.

RBRC06180, KOR1-Pitx3<-/->

RBRC No. RBRC06180
Type Wild-derived Inbred and Spontaneous Mutation
Species Mus musculus molossinus
Strain name KOR1-Pitx3<-/->
Former Common name KOR1-Pitx3
H-2 Haplotype No Data
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain development Developed by Yoshibumi Mastushima, Saitama Cancer Center, Research Institute for Clinical Oncology.
Strain description Pitx3 gene mutant mice. Spontaneous mutation arose in KOR1 mouse colony derived from Japanese wild mice (Mus musculus molossinus). Homozygous mutant mice exhibit microphthalmia. KOR1 original line (RBRC06180), C57BL/6 background (semicongenic line) (RBRC06178), BALB/c background (RBRC06179).
Colony maintenance Homozygote x Homozygote
Health Report
Gene Details
Promoter No Data
1 Symbol Pitx3
Symbol name paired-like homeodomain transcription factor 3
Chromosome 19
Common name No Data
Symbol description No Data
References

Research applications Developmental Biology Research
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
後日指定。(will be announced).
Additional information
1 No Data
Depositor Matsushima, Yoshibumi (Saitama Cancer Center) Matsushima, Yoshibumi
Strain Status /
Availability
(Expected delivery)


Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

Sperm
Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months

Live
Live mouse :

RBRC00431, Mol-Mae/Stm

RBRC No. RBRC00431
Type Wild-derived Inbred
Species Mus musculus molossinus
Strain name Mol-Mae/Stm
Former Common name M. m. molossinus Mae-1
H-2 Haplotype No Data
Background strain MAE [Mus musculus molossinus]
Appearance
1 Appearance No Data
Genotype No Data
Strain description No Data
Health Report
Gene Details
Promoter No Data
1 Symbol C8b
Symbol name complement component 8, beta subunit
Chromosome 4
Common name C8b
Symbol description No Data
References Immunogenetics. 1991;33(1):18-23.

Gene responsible for deficient activity of the beta subunit of C8, the eighth component of complement, is located on mouse chromosome 4.
Gene responsible for deficient activity of the beta subunit of C8, the eighth component of complement, is located on mouse chromosome 4.
Research applications No Data
Specific Term and Conditions No specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.)
Additional information
1 Click Here for Mouse genomic DNA (RIKEN DNA Bank)
Depositor Matsushima, Yoshibumi (Saitama Cancer Center) Matsushima, Yoshibumi
Strain Status /
Availability
(Expected delivery)


Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months
BRC mice in Publications
Title Journal
(PMID)
Author
The ancestor of extant Japanese fancy mice contributed to the mosaic genomes of classical inbred strains. Genome Res. (2013).(23604024)
Takada T, Ebata T, Noguchi H, Keane T, Adams D, Narita T, Shin-I T, Fujisawa H, Toyoda A, Abe K, Obata Y, Sakaki Y, Moriwaki K, Fujiyama A, Kohara Y, Shiroishi T.
Endogenous gammaretrovirus acquisition in Mus musculus subspecies carrying functional variants of the XPR1 virus receptor. J Virol. (2013).(23824809)
Bamunusinghe D, Liu Q, Lu X, Oler A, Kozak CA.
Devising assisted reproductive technologies for wild-derived strains of mice: 37 strains from five subspecies of Mus musculus. PLoS One.9(12) e114305: e114305 (2014).(25470728)
Mochida K, Hasegawa A, Otaka N, Hama D, Furuya T, Yamaguchi M, Ichikawa E, Ijuin M, Taguma K, Hashimoto M, Takashima R, Kadota M, Hiraiwa N, Mekada K, Yoshiki A, Ogura A.

RBRC06413, AK.Cg-Dms

RBRC No. RBRC06413
Type Spontaneous Mutation
Species Mus musculus
Strain name AK.Cg-Dms
Former Common name AK.DMS, AKR-Dms
H-2 Haplotype No Data
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain development Developed by Yoshibumi Matsushima, Saitama Cancer Center, Research Institute for Clinical Oncology.
Strain description Diabetes Mellitus Saitama, DMS. Spontaneous mutation arose in NC/Jic x KOR1 F2 generations. Heterozygous mutant mice show type 2 diabetes. Homozygous mutant mice show lethal neonatal diabetes. Under investigation (details unknown). AKR background (semicongenic) (RBRC06413), C57BL/6 background (semicongenic) (RBRC06414), BALB/c background (semicongenic) (RBRC06415), C3H background (semicongenic) (RBRC06416), DBA/2 background (semicongenic) (RBRC06417), JF1 background (semicongenic) (RBRC06418), KOR1 background(semicongenic) (RBRC06419), NC background(semicongenic) (RBRC06420).
Colony maintenance Heterozygote x Wild-type [or Crossing to AKR/NSlc]
Health Report
Gene Details
Promoter No Data
1 Symbol Insr
Symbol name insulin receptor
Chromosome 8
Common name No Data
Symbol description No Data
References No Data

Research applications Diabetes and Obesity Research,
Mouse Models for Human Disease
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
後日指定。(will be announced.)
For use of the BIOLOGICAL RESOURCE by a for-profit institution, the RECIPIENT must reach agreement on terms and conditions of use of it with DEPOSITOR and must obtain a prior written consent from the DEPOSITOR.
Additional information
1 No Data
Depositor Matsushima, Yoshibumi (Saitama Cancer Center) Matsushima, Yoshibumi
Strain Status /
Availability
(Expected delivery)


Sperm
Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months

RBRC00432, RLC/Stm

RBRC No. RBRC00432
Type Spontaneous Mutation 14wks,♂
Species Mus musculus
Strain name RLC/Stm
Former Common name No Data
H-2 Haplotype No Data
Background strain RLC/Stm
Appearance
1 Appearance albino
Genotype No Data
Strain development Spontaneous mutation originally arose in CXSN/A strain. The mutant mice were bred with a BALB/cHeA and then maintained by inbreeding.
Strain description rlc, Rupture of Lens Cataract. Spontaneous recessive mutation arose in CXSN/A mice. The mutation as a deletion of 27 bp at the end of 15th of Dock5 gene.
Health Report
Gene Details
Promoter No Data
1 Symbol Dock5
Symbol name dedicator of cytokinesis 5
Chromosome 14
Common name lr2
Symbol description No Data
References Exp Eye Res. 1997 Jan;64(1):107-13.
Genomics. 1996 Sep 15;36(3):553-4.
Graefes Arch Clin Exp Ophthalmol. 2000 Dec;238(12):970-8.

Rupture of lens cataract: a novel hereditary recessive cataract model in the mouse.
Rupture of lens cataract: a novel hereditary recessive cataract model in the mouse.
Rupture of lens cataract: a novel hereditary recessive cataract model in the mouse.
Research applications Mouse Models for Human Disease,
Sensorineural Research
Specific Term and Conditions No specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.)
Additional information
1 No Data
Depositor Matsushima, Yoshibumi (Saitama Cancer Center) Matsushima, Yoshibumi
Strain Status /
Availability
(Expected delivery)


Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months
BRC mice in Publications
Title Journal
(PMID)
Author
Pre-B lymphomas in SL/Kh mice: a multifactorial disease model. Cancer Sci.94(10): 847-850 (2003).(14556656)
Hiai H, Tsuruyama T, Yamada Y.

RBRC06415, C.Cg-Dms

RBRC No. RBRC06415
Type Spontaneous Mutation
Species Mus musculus
Strain name C.Cg-Dms
Former Common name C.DMS, BALB-Dms
H-2 Haplotype No Data
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain development Developed by Yoshibumi Matsushima, Saitama Cancer Center, Research Institute for Clinical Oncology.
Strain description Diabetes Mellitus Saitama, DMS. Spontaneous mutation arose in NC/Jic x KOR1 F2 generations. Heterozygous mutant mice show type 2 diabetes. Homozygous mutant mice show lethal neonatal diabetes. Under investigation (details unknown). AKR background (semicongenic) (RBRC06413), C57BL/6 background (semicongenic) (RBRC06414), BALB/c background (semicongenic) (RBRC06415), C3H background (semicongenic) (RBRC06416), DBA/2 background (semicongenic) (RBRC06417), JF1 background (semicongenic) (RBRC06418), KOR1 background(semicongenic) (RBRC06419), NC background(semicongenic) (RBRC06420).
Colony maintenance Heterozygote x Wild-type [or Crossing to BALB/cCrSlc]
Health Report
Gene Details
Promoter No Data
1 Symbol Insr
Symbol name insulin receptor
Chromosome 8
Common name No Data
Symbol description No Data
References No Data

Research applications Diabetes and Obesity Research,
Mouse Models for Human Disease
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
後日指定。(will be announced.)
For use of the BIOLOGICAL RESOURCE by a for-profit institution, the RECIPIENT must reach agreement on terms and conditions of use of it with DEPOSITOR and must obtain a prior written consent from the DEPOSITOR.
Additional information
1 No Data
Depositor Matsushima, Yoshibumi (Saitama Cancer Center) Matsushima, Yoshibumi
Strain Status /
Availability
(Expected delivery)


Sperm
Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months