RBRC00933, GATA-1 promoter-LacZ mice ITintdUE IEintLacZ 398 line

RBRC No. RBRC00933
Type TransgeneCartagena
Species Mus musculus
Strain name GATA-1 promoter-LacZ mice ITintdUE IEintLacZ 398 line
Former Common name No Data
H-2 Haplotype No Data
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain description No Data
Health Report No Data
Gene Details
Promoter mouse GATA-1 promoter
1 Symbol lacZ
Symbol name beta-galactosidase (E. coli)
Chromosome UN
Common name No Data
Symbol description E. coli beta galactosidase
References Proc Natl Acad Sci U S A. 1997 Apr 29;94(9):4487-92.

GATA-1 transcription is controlled by distinct regulatory mechanisms during primitive and definitive erythropoiesis.
Research applications No Data
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR.
In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
The depositor should be a co-author in articles when the users publish their data using these mice for 2 year after provided. Users should contact the depositor in the case of application for any patents with the results from these mice.
Additional information
1 Lab HP (Japanese)
Depositor Yamamoto, Masayuki (University of tsukuba) Yamamoto, Masayuki
Strain Status /
Availability
(Expected delivery)


Preparing for distribution
Preparing for distribution
(Please note that it may take more than 6 months to make arrangements to distribute.)

Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

RBRC00984, ICR;129P2-Nfe2l2<tm1Mym>/MymRbrc

RBRC No. RBRC00984
Type Targeted MutationCartagena
Species Mus musculus
Strain name ICR;129P2-Nfe2l2<tm1Mym>/MymRbrc
Former Common name Nrf2 knock out mouse (ICR background)
H-2 Haplotype No Data
ES cell line E14 [129P2/OlaHsd]
Donor strain 129P2/OlaHsd via E14 ES cell line
Background strain Jcl:ICR
Appearance
1 Appearance No Data
Genotype No Data
Strain development Developed by Masayuki Yamamoto, Institute of Basic Medical Sciences and Center for Tsukuba Advanced Research Alliance, University of Tsukuba in 1996. The targeting vector containing lacZ-neo cassette was transferred into E14 ES cells to replace the 1.2 kb segment containing the rest of the exon 5 coding sequence of the Nrf2 gene.
Strain description Nrf2 (Nfe2l2) Knockout mice. This strain is a useful model for the in vivo analysis of chemical carcinogenesis and resistance to anti-cancer drugs. A phenolic antioxidant significantly induced the expression of phase II enzymes such as glutathione S-transferase and NAD(P)H: quinone oxidoreductase in normal mice. However, in the homozygous Nrf2 deficient mice the induction of the phase II enzymes by a phenolic antioxidant was largely eliminated in the liver and intestine. Since Nrf2 is constantly degraded by proteasome under normal condition, it is hardly to detect Nrf2 protein in the absence of stimuli. Electrophilic chemicals, such as DEM (diethyl maleate) and tBHQ (tert-buthyl hydroquinone), are generally used to stabilize Nrf2. Or proteasomal inhibitors, such as MG132, are also effective increasing the protein amount of Nrf2. C57BL/6 background (RBRC01390), BALB/c background (RBRC02190), A/J background (RBRC02414), ICR mixed background (RBRC00984). Homozygous mutant mice are viable and fertile, but show lower reproductive performance.
Colony maintenance Homozygote x Heterozygote [or Crossing to Jcl:ICR]
Health Report No Data
Gene Details
Promoter No Data
1 Symbol Nfe2l2
Symbol name nuclear factor, erythroid derived 2, like 2
Chromosome 2
Common name Nrf2
Symbol description No Data
2 Symbol lacZ
Symbol name beta-galactosidase (E. coli)
Chromosome 2
Common name No Data
Symbol description E. coli beta galactosidase
3 Symbol nls
Symbol name SV40 large T antigen nuclear localization signal (NLS)
Chromosome 2
Common name No Data
Symbol description No Data
Promoter herpes simplex virus thymidine kinase promoter (HSV tk promoter)
4 Symbol neo
Symbol name neomycin resistance gene (E. coli)
Chromosome 2
Common name neo; neomycin;
Symbol description No Data
References Biochem Biophys Res Commun. 1997 Jul 18;236(2):313-22.

An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements.
Research applications No Data
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
Biochem. Biophys. Res. Commun., 236, 313-322 (1997).
In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
The depositor should be a co-author in the articles when the users publish their data using these mice for 2 year after provided.
Any patent rights and other intellectual properties are retained by the depositor. Users should contact the depositor in the case of application for any patents with the results from these mice.
Additional information
1 Lab HP (Japanese)
2 Mouse of the Month Oct 2005
Mouse of the Month Apr 2012
3 Genotyping protocol <PCR>
Depositor Yamamoto, Masayuki (University of tsukuba) Yamamoto, Masayuki
Strain Status /
Availability
(Expected delivery)


Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

Sperm
Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months
BRC mice in Publications
Title Journal
(PMID)
Author
Dietary sulforaphane, a histone deacetylase inhibitor for cancer prevention. J Nutr.139(12): 178756 (2009).(19812222)
Ho E, Clarke JD, Dashwood RH.
The transcriptome of Nrf2-/- mice provides evidence for impaired cell cycle progression in the development of cigarette smoke-induced emphysematous changes. Toxicol Sci.115(1): 238-52 (2010).(20133372)
Gebel S, Diehl S, Pype J, Friedrichs B, Weiler H, Sch ller J, Xu H, Taguchi K, Yamamoto M, M ller T.
Metabolism and Tissue Distribution of Sulforaphane in Nrf2 Knockout and Wild-Type Mice. Pharm Res. (2011).(21681606)
Clarke JD, Hsu A, Williams DE, Dashwood RH, Stevens JF, Yamamoto M, Ho E.
Developmental role of nuclear factor E2-related factor 2 in mitigating methamphetamine fetal toxicity and postnatal neurodevelopmental deficits. Free Radic Biol Med.65C: 620-631 (2013).(23932974)
Ramkissoon A, Wells PG.
Methamphetamine Oxidative Stress, Neurotoxicity, And Functional Deficits Are Modulated By Nuclear Factor-E2-Related Factor 2. Free Radic. Biol. Med. (2015).(26427884)
Ramkissoon A, Wells PG.

RBRC06307, ICR;129(B6)-Mafk<tm1.1Jeng>

RBRC No. RBRC06307
Type Targeted MutationCartagena
Species Mus musculus
Strain name ICR;129(B6)-Mafk<tm1.1Jeng>
Former Common name MafK KO
H-2 Haplotype No Data
ES cell line R1 [(129X1/SvJ x 129S1/Sv)F1-Kitl<+>]
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain development Developed by University of Michigan, Douglas Engel and Masayuki Yamamoto, Institute of Basic Medical Sciences and Center for TARA, University of Tsukuba. R1 RS cells were used for generation of the mice. 129, C57BL/6 and ICR mixed background. A MC1-TK MC1-neo cassette of MafF KO (RBRC06305) and MafG KO (RBRC06306) mice was removed by crossing with Ayu1-cre mice. A PGK-neo cassette of MafK KO mice (RBRC06307) was removed by crossing with Ayu1-cre mice.
Strain description Small Maf protein genes knockout mice (MafF: RBRC06305, MafG: RBRC06306 and MafK: RBRC06307). Both MafF and MafK homozygous mutant mice show no obvious abnormality. MafG homozygous mutant mice exhibit impaired platelet formation accompanied by megakaryocyte proliferation, as well as mild behavioral abnormalities. MafF, MafG and MafK triple homozygous mutant mice are embryonic lethal (around E11.5).
Colony maintenance Homozygote x Homozygote [or Crossing to Jcl:ICR]
Health Report
Gene Details
Promoter No Data
1 Symbol Mafk
Symbol name v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian)
Chromosome 5
Common name No Data
Symbol description No Data
2 Symbol lacZ
Symbol name beta-galactosidase (E. coli)
Chromosome 5
Common name No Data
Symbol description No Data
3 Symbol loxP
Symbol name phage P1 loxP
Chromosome 5
Common name No Data
Symbol description No Data
4 Symbol nls
Symbol name SV40 large T antigen nuclear localization signal (NLS)
Chromosome 5
Common name No Data
Symbol description No Data
References

Research applications Cre/loxP system,
Fluorescent Proteins/lacZ System,
Neurobiology Research
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
Genes Dev., 12, 2164-2174 (1998).
Additional information
1 Lab HP (Japanese)
2 Genotyping protocol <PCR>
Depositor Yamamoto, Masayuki (Tohoku Medical Megabank Organization) Yamamoto, Masayuki
Strain Status /
Availability
(Expected delivery)


Sperm
Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months

RBRC00917, GATA-1 promoter-LacZ mice ITintIEintLacZ 114 line

RBRC No. RBRC00917
Type TransgeneCartagena
Species Mus musculus
Strain name GATA-1 promoter-LacZ mice ITintIEintLacZ 114 line
Former Common name No Data
H-2 Haplotype No Data
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain description No Data
Health Report No Data
Gene Details
Promoter mouse GATA-1 promoter
1 Symbol lacZ
Symbol name beta-galactosidase (E. coli)
Chromosome UN
Common name No Data
Symbol description E. coli beta galactosidase
References Proc Natl Acad Sci U S A. 1997 Apr 29;94(9):4487-92.

GATA-1 transcription is controlled by distinct regulatory mechanisms during primitive and definitive erythropoiesis.
Research applications No Data
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
Proc. Natl. Acad. Sci. U.S.A. 94, 4487-4492 (1997).
In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
The depositor should be a co-author in articles when the users publish their data using these mice for 2 year after provided. Users should contact the depositor in the case of application for any patents with the results from these mice.
Additional information
1 Lab HP (Japanese)
Depositor Yamamoto, Masayuki (University of tsukuba) Yamamoto, Masayuki
Strain Status /
Availability
(Expected delivery)


Preparing for distribution
Preparing for distribution
(Please note that it may take more than 6 months to make arrangements to distribute.)

Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

RBRC00934, GATA-1 promoter-LacZ mice ITintdUE IEintLacZ 715 line

RBRC No. RBRC00934
Type TransgeneCartagena
Species Mus musculus
Strain name GATA-1 promoter-LacZ mice ITintdUE IEintLacZ 715 line
Former Common name No Data
H-2 Haplotype No Data
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain description No Data
Health Report No Data
Gene Details
Promoter mouse GATA-1 promoter
1 Symbol lacZ
Symbol name beta-galactosidase (E. coli)
Chromosome UN
Common name No Data
Symbol description E. coli beta galactosidase
References Proc Natl Acad Sci U S A. 1997 Apr 29;94(9):4487-92.

GATA-1 transcription is controlled by distinct regulatory mechanisms during primitive and definitive erythropoiesis.
Research applications No Data
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR.
In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
The depositor should be a co-author in articles when the users publish their data using these mice for 2 year after provided. Users should contact the depositor in the case of application for any patents with the results from these mice.
Additional information
1 Lab HP (Japanese)
Depositor Yamamoto, Masayuki (University of tsukuba) Yamamoto, Masayuki
Strain Status /
Availability
(Expected delivery)


Preparing for distribution
Preparing for distribution
(Please note that it may take more than 6 months to make arrangements to distribute.)

Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

RBRC01208, B6.Cg-Tg(G1-HRD-EGFP)28Mym/MymRbrc

RBRC No. RBRC01208
Type TransgeneCartagena
Species Mus musculus
Strain name B6.Cg-Tg(G1-HRD-EGFP)28Mym/MymRbrc
Former Common name GATA-1-GFP Tg, GATA-1-HRD-GFP line 28/B6
H-2 Haplotype No Data
Background strain C57BL/6JJcl
Appearance
1 Appearance No Data
Genotype No Data
Strain description No Data
Health Report No Data
Gene Details
Promoter No Data
1 Symbol Gata1
Symbol name GATA binding protein 1
Chromosome UN
Common name Gata-1, Gf-1
Symbol description No Data
Promoter mouse GATA-1 hematopoietic regulatory domain
2 Symbol GFP
Symbol name Green Fluorescent Protein (Jellyfish)
Chromosome UN
Common name No Data
Symbol description No Data
References Blood. 2003 Nov 15;102(10):3575-83. Epub 2003 Jul 31.

Identification and characterization of 2 types of erythroid progenitors that express GATA-1 at distinct levels.
Research applications Fluorescent Proteins/lacZ System,
Hematological Research
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
Blood, 102, 3575-3583 (2003).
In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
The DEPOSITOR should be a co-author in the articles when the users publish their data using these mice for 2 year after deposition to the RIKEN BRC. Users should contact the DEPOSITOR in the case of application for any patents with the results from these mice.
Additional information
1 GFP Transfer License (Japanese / English)
Please fill in the Schedule A, and submit two signed copies to us together with two signed copies of RIKEN BRC’s MTA. Please also read Schedule B.
Lab HP (Japanese)
2 Genotyping protocol <PCR>
Depositor Yamamoto, Masayuki (University of tsukuba) Yamamoto, Masayuki
Strain Status /
Availability
(Expected delivery)


Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

RBRC09400, STOCK Tg(Gata1-GFP)357Mym

RBRC No. RBRC09400
Type TransgeneCartagena
Species Mus musculus
Strain name STOCK Tg(Gata1-GFP)357Mym
Former Common name G1BAC-GFP Tg mouse line 357
H-2 Haplotype No Data
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain development Developed by Masayuki Yamamoto, Faculty of Medicine, University of Tsukuba in 2003. A BAC DNA construct was injected into fertilized eggs from BDF1 background. Mice were maintained in a mixed background of BDF1 and ICR.
Strain description BAC transgenic mice in which GFP is under the control of the Gata1 gene promoter.
Colony maintenance Heterozygote x Wild-type [C57BL/6JJcl]
Health Report
Gene Details
Promoter No Data
1 Symbol Frt
Symbol name yeast FRT (flippase recombination target) site
Chromosome UN
Common name No Data
Symbol description No Data
2 Symbol loxP
Symbol name phage P1 loxP
Chromosome UN
Common name No Data
Symbol description No Data
Promoter mouse Gata1 promoter
3 Symbol GFP
Symbol name Green Fluorescent Protein (Jellyfish)
Chromosome UN
Common name No Data
Symbol description No Data
References No Data

Research applications Fluorescent Proteins/lacZ System
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
Mol. Cell Biol., 29, 1163-1175 (2009).
In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
In publiching the research results to be obtained by use of the BOLOGOCAL RESOURCE, involving the DEPOSITOR in author byline is requested (by May 2018).
Additional information
1 GFP Transfer License (Japanese / English)
Please fill in the Schedule A, and submit two signed copies to us together with two signed copies of RIKEN BRC’s MTA. Please also read Schedule B.
2 Genotyping protocol <PCR>
Depositor Yamamoto, Masayuki (Tohoku university) Yamamoto, Masayuki
Strain Status /
Availability
(Expected delivery)


Sperm
Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months

Live
Live mouse :

RBRC00918, GATA-1 promoter-LacZ mice ITintIEintLacZ 226 line

RBRC No. RBRC00918
Type TransgeneCartagena
Species Mus musculus
Strain name GATA-1 promoter-LacZ mice ITintIEintLacZ 226 line
Former Common name No Data
H-2 Haplotype No Data
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain description No Data
Health Report No Data
Gene Details
Promoter mouse GATA-1 promoter
1 Symbol lacZ
Symbol name beta-galactosidase (E. coli)
Chromosome UN
Common name No Data
Symbol description E. coli beta galactosidase
References Proc Natl Acad Sci U S A. 1997 Apr 29;94(9):4487-92.

GATA-1 transcription is controlled by distinct regulatory mechanisms during primitive and definitive erythropoiesis.
Research applications No Data
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
Proc. Natl. Acad. Sci. U.S.A. 94, 4487-4492 (1997).
In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
The depositor should be a co-author in articles when the users publish their data using these mice for 2 year after provided. Users should contact the depositor in the case of application for any patents with the results from these mice.
Additional information
1 Lab HP (Japanese)
Depositor Yamamoto, Masayuki (University of tsukuba) Yamamoto, Masayuki
Strain Status /
Availability
(Expected delivery)


Preparing for distribution
Preparing for distribution
(Please note that it may take more than 6 months to make arrangements to distribute.)

Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

RBRC00935, GATA-1 promoter-LacZ mice ITintdUE IEintLacZ 865 line

RBRC No. RBRC00935
Type TransgeneCartagena
Species Mus musculus
Strain name GATA-1 promoter-LacZ mice ITintdUE IEintLacZ 865 line
Former Common name No Data
H-2 Haplotype No Data
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain description No Data
Health Report No Data
Gene Details
Promoter mouse GATA-1 promoter
1 Symbol lacZ
Symbol name beta-galactosidase (E. coli)
Chromosome UN
Common name No Data
Symbol description E. coli beta galactosidase
References Proc Natl Acad Sci U S A. 1997 Apr 29;94(9):4487-92.

GATA-1 transcription is controlled by distinct regulatory mechanisms during primitive and definitive erythropoiesis.
Research applications No Data
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR.
In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
The depositor should be a co-author in articles when the users publish their data using these mice for 2 year after provided. Users should contact the depositor in the case of application for any patents with the results from these mice.
Additional information
1 Lab HP (Japanese)
Depositor Yamamoto, Masayuki (University of tsukuba) Yamamoto, Masayuki
Strain Status /
Availability
(Expected delivery)


Preparing for distribution
Preparing for distribution
(Please note that it may take more than 6 months to make arrangements to distribute.)

Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

RBRC01236, STOCK Ahr<tm1Yfk> Nfe2l2<tm1Mym>

RBRC No. RBRC01236
Type Targeted MutationCartagena
Species Mus musculus
Strain name STOCK Ahr<tm1Yfk> Nfe2l2<tm1Mym>
Former Common name Nrf2(+/-)::AhR(+/-) compound mouse
H-2 Haplotype No Data
Donor strain B6;129S6-Ahrtm1Yfk and STOCK-Nfe2l2tm1Yin
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain description No Data
Health Report
Gene Details
Promoter No Data
1 Symbol Ahr
Symbol name aryl-hydrocarbon receptor
Chromosome 12
Common name Ah, Ahh, Ahre, dioxin receptor, In
Symbol description No Data
2 Symbol lacZ
Symbol name beta-galactosidase (E. coli)
Chromosome 12
Common name No Data
Symbol description E. coli beta galactosidase
3 Symbol nls
Symbol name SV40 large T antigen nuclear localization signal (NLS)
Chromosome 12
Common name No Data
Symbol description No Data
4 Symbol Nfe2l2
Symbol name nuclear factor, erythroid derived 2, like 2
Chromosome 2
Common name Nrf2
Symbol description No Data
5 Symbol lacZ
Symbol name beta-galactosidase (E. coli)
Chromosome 2
Common name No Data
Symbol description E. coli beta galactosidase
6 Symbol nls
Symbol name SV40 large T antigen nuclear localization signal (NLS)
Chromosome 2
Common name No Data
Symbol description No Data
Promoter herpes simplex virus thymidine kinase promoter (HSV tk promoter)
7 Symbol neo
Symbol name neomycin resistance gene (E. coli)
Chromosome 12
Common name neo; neomycin;
Symbol description No Data
8 Symbol neo
Symbol name neomycin resistance gene (E. coli)
Chromosome 2
Common name neo; neomycin;
Symbol description No Data
References Biochem Biophys Res Commun. 1997 Jul 18;236(2):313-22.
Biochem Biophys Res Commun. 2003 Mar 28;303(1):105-11.
Genes Cells. 1997 Oct;2(10):645-54.

An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements.
An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements.
An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements.
Research applications Cell Biology Research
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
Noda S.et al. (2003) BIochem Biophys Res Commun. 303:105-111.
In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
The RECIPIENT agrees to include the DEPOSITOR/DEVELOPER as a co-author in any publications resulted by the use of the BIOLOGICAL RESOURCE during the first 2 years after deposition by the DEPOSITOR to the RIKEN BRC. The RECIPIENT should contact the DEPOSITOR in the case of application for any patents or commercial use with the results from the use of the BIOLOGICAL RESOURCE.
Additional information
1 Lab HP (Japanese)
Depositor Yamamoto, Masayuki (University of tsukuba) Yamamoto, Masayuki
Strain Status /
Availability
(Expected delivery)


Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months