RBRC05990, ICR;D2-Tg(Hes7-Hes7,venus)1Kag

RBRC No. RBRC05990
Type TransgeneCartagena
Species Mus musculus
Strain name ICR;D2-Tg(Hes7-Hes7,venus)1Kag
Former Common name Hes7 Tg ; Hes7-Hes7/venus Tg
H-2 Haplotype No Data
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain development Developed by Ryoichiro Kageyama, Institute for Virus Research, Kyoto University in 2003. The transgene was injected into the pronuclei of DBA/2 fertilized eggs.
Strain description Hes7 transgenic mice Transgene composed of 5.4kb Hes7 promoter-1st exon-1st intron-2nd exon-Hes7 cDNA(ORF of the 1st&2nd exons are deleted)-IRES-Venus-SV40 polyA Hes7 expression is up-regulated and initially oscillates but later becomes sustained.
Colony maintenance Carrier x Noncarrier [or Crossing to Slc:ICR]
Health Report No Data
Gene Details
Promoter No Data
1 Symbol Hes7
Symbol name hairy and enhancer of split 7 (Drosophila)
Chromosome UN
Common name No Data
Symbol description No Data
2 Symbol Ires
Symbol name internal ribosomal entry site (EMCV)
Chromosome UN
Common name No Data
Symbol description No Data
3 Symbol Venus
Symbol name Green Fluorescent Protein, F46L (Jellyfish)
Chromosome UN
Common name No Data
Symbol description No Data
4 Symbol No Data
Symbol name SV40 polyA
Chromosome No Data
Common name No Data
Symbol description No Data
References Dev Cell. 2007 Aug;13(2):298-304.

The initiation and propagation of Hes7 oscillation are cooperatively regulated by Fgf and notch signaling in the somite segmentation clock.
Research applications No Data
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
Dev Cell. 2007 13(2):298-304.
In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
The availability of the BIOLOGICAL RESOURCE is limited to a RECIPIENT of a not-for profit institution for a not-for-profit research. The RECIPIENT of BIOLOGICAL resource shall obtain a prior written consent on use of it from the DEPOSITOR Dr. Ryoichiro Kageyama (E-mail: rkageyam@virus.kyoto-u.ac.jp ). (No approval form (Form D) is necessary).
Additional information
1 No Data
Depositor Kageyama, Ryoichiro (Institute for Virus Research, Kyoto University) Kageyama, Ryoichiro
Strain Status /
Availability
(Expected delivery)


Preparing for distribution
Preparing for distribution
(Please note that it may take more than 6 months to make arrangements to distribute.)

Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

RBRC05991, ICR;D2-Tg(Hes1-Ub1Luc)Ckag

RBRC No. RBRC05991
Type TransgeneCartagena
Species Mus musculus
Strain name ICR;D2-Tg(Hes1-Ub1Luc)Ckag
Former Common name pHes1-Ub-luc (LineC) ; Hes1-luc Tg#C
H-2 Haplotype No Data
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain development Developed by Ryoichiro Kageyama, Institute for Virus Research, Kyoto University in 2004. The transgene was injected into the pronuclei of DBA/2 fertilized eggs.
Strain description Hes1-luc transgenic mice. Destabilized luciferase (Ub1-luc) is expressed under the control of Hes1 promoter.
Colony maintenance Carrier x Noncarrier [or Crossing to Slc:ICR]
Health Report No Data
Gene Details
Promoter mouse Hes1 promoter, human ubiquitin
1 Symbol luc
Symbol name optimized luciferase (synthetic)
Chromosome UN
Common name No Data
Symbol description No Data
References Proc Natl Acad Sci U S A. 2006 Jan 31;103(5):1313-8. Epub 2006 Jan 23.

Real-time imaging of the somite segmentation clock: Revelation of unstable oscillators in the individual presomitic mesoderm cells.
Research applications No Data
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
Proc Natl Acad Sci U S A. 2006 103(5):1313-8.
In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
The availability of the BIOLOGICAL RESOURCE is limited to a RECIPIENT of a not-for profit institution for a not-for-profit research. The RECIPIENT of BIOLOGICAL resource shall obtain a prior written consent on use of it from the DEPOSITOR Dr. Ryoichiro Kageyama (E-mail: rkageyam@virus.kyoto-u.ac.jp ). (No approval form (Form D) is necessary).
Additional information
1 No Data
Depositor Kageyama, Ryoichiro (Institute for Virus Research, Kyoto University) Kageyama, Ryoichiro
Strain Status /
Availability
(Expected delivery)


Preparing for distribution
Preparing for distribution
(Please note that it may take more than 6 months to make arrangements to distribute.)

Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

RBRC05992, ICR;D2-Tg(H7-UbLuc-In)3Kag

RBRC No. RBRC05992
Type TransgeneCartagena
Species Mus musculus
Strain name ICR;D2-Tg(H7-UbLuc-In)3Kag
Former Common name pHes7-Ub-luc (Line3) ; Hes7-luc Tg#3
H-2 Haplotype No Data
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain development Developed by Ryoichiro Kageyama, Institute for Virus Research, Kyoto University in 2004. The transgene was injected into the pronuclei of DBA/2 fertilized eggs.
Strain description Hes7-luc transgenic mice. Destabilized luciferase (Ub-luc) is expressed under the control of Hes7 promoter.
Colony maintenance Carrier x Noncarrier [or Crossing to Slc:ICR]
Health Report No Data
Gene Details
Promoter No Data
1 Symbol HA
Symbol name human influenza virus HA (hemagglutinin) tag sequence
Chromosome UN
Common name No Data
Symbol description No Data
Promoter mouse Hes7 promoter, human ubiquitin
2 Symbol luc
Symbol name optimized luciferase (synthetic)
Chromosome UN
Common name No Data
Symbol description No Data
References

Research applications No Data
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
Proc Natl Acad Sci U S A. 2011 108(8):3300-5.
In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
The availability of the BIOLOGICAL RESOURCE is limited to a RECIPIENT of a not-for profit institution for a not-for-profit research. The RECIPIENT of BIOLOGICAL resource shall obtain a prior written consent on use of it from the DEPOSITOR Dr. Ryoichiro Kageyama (E-mail: rkageyam@virus.kyoto-u.ac.jp ). (No approval form (Form D) is necessary).
Additional information
1 No Data
Depositor Kageyama, Ryoichiro (Institute for Virus Research, Kyoto University) Kageyama, Ryoichiro
Strain Status /
Availability
(Expected delivery)


Preparing for distribution
Preparing for distribution
(Please note that it may take more than 6 months to make arrangements to distribute.)

Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

RBRC05993, ICR.Cg-Hes7<tm3Kag>

RBRC No. RBRC05993
Type Targeted Mutation CongenicCartagena
Species Mus musculus
Strain name ICR.Cg-Hes7<tm3Kag>
Former Common name Hes7 intron-les ; Hes7 KO/intronless
H-2 Haplotype No Data
ES cell line TT2 [(C57BL/6NCrlj x CBA/JNCrlj)F1]
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain development Developed by Ryoichiro Kageyama, Institute for Virus Research, Kyoto University in 2007. TT2 ES cells were used. The mutant mice were crossed to ICR.
Strain description Intronless He7 mice. The intron sequence of Hes7 were removed. The The floxed neo cassette was removed by transient expresion of cre recombinase.
Colony maintenance Heterozygote x Wild-type [or Crossing to Slc:ICR]
Health Report No Data
Gene Details
Promoter No Data
1 Symbol Hes7
Symbol name hairy and enhancer of split 7 (Drosophila)
Chromosome 11
Common name No Data
Symbol description No Data
2 Symbol loxP
Symbol name phage P1 loxP
Chromosome 11
Common name No Data
Symbol description No Data
References

Research applications Cre/loxP system
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
Proc Natl Acad Sci U S A. 2011 108(8):3300-5.
In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
The availability of the BIOLOGICAL RESOURCE is limited to a RECIPIENT of a not-for profit institution for a not-for-profit research. The RECIPIENT of BIOLOGICAL resource shall obtain a prior written consent on use of it from the DEPOSITOR Dr. Ryoichiro Kageyama (E-mail: rkageyam@virus.kyoto-u.ac.jp ). (No approval form (Form D) is necessary).
Additional information
1 No Data
Depositor Kageyama, Ryoichiro (Institute for Virus Research, Kyoto University) Kageyama, Ryoichiro
Strain Status /
Availability
(Expected delivery)


Preparing for distribution
Preparing for distribution
(Please note that it may take more than 6 months to make arrangements to distribute.)

Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

RBRC05994, ICR;D2-Tg(H7-UbLuc-In*del)1Kag

RBRC No. RBRC05994
Type TransgeneCartagena
Species Mus musculus
Strain name ICR;D2-Tg(H7-UbLuc-In*del)1Kag
Former Common name pHes7-Ub-luc (intron-less) ; Hes7-luc/dIn Tg
H-2 Haplotype No Data
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain development Developed by Ryoichiro Kageyama, Institute for Virus Research, Kyoto University in 2008. The transgene was injected into the pronuclei of DBA/2 fertilized eggs.
Strain description pH7-UbLuc-In (-) (intoronless) transgenic mice. destabilized luciferase (Ub-Luc) is expressed under the control of Hes7 promoter.
Colony maintenance Carrier x Noncarrier [or Crossing to Slc:ICR]
Health Report No Data
Gene Details
Promoter No Data
1 Symbol HA
Symbol name human influenza virus HA (hemagglutinin) tag sequence
Chromosome No Data
Common name No Data
Symbol description No Data
Promoter mouse Hes7 promoter, human ubiquitin
2 Symbol luc
Symbol name optimized luciferase (synthetic)
Chromosome UN
Common name No Data
Symbol description No Data
References

Research applications No Data
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
Proc Natl Acad Sci U S A. 2011 108(8):3300-5.
In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
The availability of the BIOLOGICAL RESOURCE is limited to a RECIPIENT of a not-for profit institution for a not-for-profit research. The RECIPIENT of BIOLOGICAL resource shall obtain a prior written consent on use of it from the DEPOSITOR Dr. Ryoichiro Kageyama (E-mail: rkageyam@virus.kyoto-u.ac.jp ). (No approval form (Form D) is necessary).
Additional information
1 No Data
Depositor Kageyama, Ryoichiro (Institute for Virus Research, Kyoto University) Kageyama, Ryoichiro
Strain Status /
Availability
(Expected delivery)


Preparing for distribution
Preparing for distribution
(Please note that it may take more than 6 months to make arrangements to distribute.)

Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months