RBRC10018, C57BL/6-Tg(Myh6-Kcnj8)634Kcmm

RBRC No. RBRC10018
Type TransgeneCartagena
Species Mus musculus
Strain name C57BL/6-Tg(Myh6-Kcnj8)634Kcmm
Former Common name Kir6.1-TGWT#634
H-2 Haplotype No Data
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain description No Data
Health Report No Data
Gene Details
Promoter No Data
1 Symbol GH
Symbol name Growth hormone polyA (human)
Chromosome UN
Common name No Data
Symbol description No Data
Promoter mouse Myh6 promoter
2 Symbol Kcnj8
Symbol name potassium inwardly-rectifying channel, subfamily J, member 8 (rat)
Chromosome UN
Common name No Data
Symbol description No Data
References No Data

Research applications Cardiovascular Research,
Diabetes and Obesity Research
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form.
The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE.
Additional information
1 No Data
Depositor Seino, Susumu (Chiba University) Seino, Susumu
Strain Status /
Availability
(Expected delivery)


Sperm
Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months

RBRC10019, C57BL/6-Tg(Myh6-Kcnj8)673Kcmm

RBRC No. RBRC10019
Type TransgeneCartagena
Species Mus musculus
Strain name C57BL/6-Tg(Myh6-Kcnj8)673Kcmm
Former Common name Kir6.1-TGWT#673
H-2 Haplotype No Data
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain description No Data
Health Report No Data
Gene Details
Promoter No Data
1 Symbol GH
Symbol name Growth hormone polyA (human)
Chromosome UN
Common name No Data
Symbol description No Data
Promoter mouse Myh6 promoter
2 Symbol Kcnj8
Symbol name potassium inwardly-rectifying channel, subfamily J, member 8 (rat)
Chromosome UN
Common name No Data
Symbol description No Data
References No Data

Research applications Cardiovascular Research,
Diabetes and Obesity Research
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form.
The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE.
Additional information
1 No Data
Depositor Seino, Susumu (Chiba University) Seino, Susumu
Strain Status /
Availability
(Expected delivery)


Sperm
Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months

RBRC10082, B6-Kcnj11<tm2.1Sse>

RBRC No. RBRC10082
Type Targeted MutationCartagena
Species Mus musculus
Strain name B6-Kcnj11<tm2.1Sse>
Former Common name Kir6.2-floxed delta neo mice
H-2 Haplotype No Data
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain description No Data
Health Report
Gene Details
Promoter No Data
1 Symbol Frt
Symbol name yeast FRT (flippase recombination target) site
Chromosome 7
Common name No Data
Symbol description No Data
2 Symbol Kcnj11
Symbol name potassium inwardly rectifying channel, subfamily J, member 11
Chromosome 7
Common name No Data
Symbol description No Data
3 Symbol loxP
Symbol name phage P1 loxP
Chromosome 7
Common name No Data
Symbol description No Data
4 Symbol loxP
Symbol name phage P1 loxP
Chromosome 7
Common name No Data
Symbol description No Data
References No Data

Research applications Cre/loxP system,
FLP/frt system
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form.
Additional information
1 No Data
2 Genotyping protocol <PCR>
Depositor Seino, Susumu (Kobe University) Seino, Susumu
Strain Status /
Availability
(Expected delivery)


Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

Sperm
Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months

Live
Live mouse :

RBRC05879, B6;129P2-Kcnj11<tm1Sse>

RBRC No. RBRC05879
Type Targeted MutationCartagena
Species Mus musculus
Strain name B6;129P2-Kcnj11<tm1Sse>
Former Common name Kir6.2 KO, B6-Kcnj11 KO
H-2 Haplotype No Data
ES cell line E14 [129P2/OlaHsd]
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain development Developed by Dr. Takashi Miki and Susumu Seino, Chiba University Graduate School of Medicine in 1998. E14 ES cells were used. The mutant mice were backcrossed to C57BL/6J over 5 generations.
Strain description Kcnj11 gene knockout mice. An exon of Kcnj11 gene was disrupted by neomycin resistance gene insertion. Homozygous mutant mice are viable and fertile, but show a somewhat low reproductive performance (nurturing) compared to wild-type.
Colony maintenance Heterozygote, Homozygote x Homozygote [or Crossing to C57BL/6JJcl]
Health Report
Gene Details
Promoter No Data
1 Symbol Kcnj11
Symbol name potassium inwardly rectifying channel, subfamily J, member 11
Chromosome 7
Common name No Data
Symbol description No Data
Promoter mouse phosphoglycerate kinase promoter (PGK promoter)
2 Symbol neo
Symbol name neomycin resistance gene (E. coli)
Chromosome 7
Common name neo; neomycin;
Symbol description No Data
References

Research applications Neurobiology Research
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
Proc Natl Acad Sci U S A. 1998 95(18):10402-6.
The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE.
Additional information
1 No Data
2 Genotyping protocol <PCR>
Depositor Seino, Susumu (Kobe University) Seino, Susumu
Strain Status /
Availability
(Expected delivery)


Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

Sperm
Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months

RBRC09391, B6;129-Rapgef4<tm1Sse>

RBRC No. RBRC09391
Type Targeted MutationCartagena
Species Mus musculus
Strain name B6;129-Rapgef4<tm1Sse>
Former Common name Epac2-flox
H-2 Haplotype No Data
ES cell line R1 [(129X1/SvJ x 129S1/Sv)F1-Kitl<+>]
Background strain C57BL/6JJcl
Appearance
1 Appearance No Data
Genotype No Data
Strain description No Data
Health Report
Gene Details
Promoter No Data
1 Symbol Rapgef4
Symbol name Rap guanine nucleotide exchange factor (GEF) 4
Chromosome 2
Common name Epac2
Symbol description No Data
2 Symbol loxP
Symbol name phage P1 loxP
Chromosome 2
Common name No Data
Symbol description No Data
Promoter herpes simplex virus thymidine kinase promoter (HSV tk promoter)
3 Symbol neo
Symbol name neomycin resistance gene (E. coli)
Chromosome 2
Common name No Data
Symbol description No Data
References No Data

Research applications Cre/loxP system,
Endocrine Deficiency Research
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form.
Additional information
1 No Data
2 Genotyping protocol <PCR>
Depositor Seino, Susumu (Kobe University) Seino, Susumu
Strain Status /
Availability
(Expected delivery)


Sperm
Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months

RBRC09392, B6;129-Rims2<tm1Sse>

RBRC No. RBRC09392
Type Targeted MutationCartagena
Species Mus musculus
Strain name B6;129-Rims2<tm1Sse>
Former Common name Rim2a-KO; Rim2 alpha-
H-2 Haplotype No Data
ES cell line Not specified (ES cell)
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain description No Data
Health Report No Data
Gene Details
Promoter No Data
1 Symbol Rims2
Symbol name regulating synaptic membrane exocytosis 2
Chromosome 15
Common name No Data
Symbol description No Data
2 Symbol neo
Symbol name neomycin resistance gene (E. coli)
Chromosome 15
Common name No Data
Symbol description No Data
References No Data

Research applications Endocrine Deficiency Research
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
Cell Metab,, 12(2):117-129 (2010).
In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
Additional information
1 No Data
Depositor Seino, Susumu (Kobe University) Seino, Susumu
Strain Status /
Availability
(Expected delivery)


Preparing for distribution
Preparing for distribution
(Please note that it may take more than 6 months to make arrangements to distribute.)

Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

RBRC09393, B6-Kcnj11<tm2Sse>

RBRC No. RBRC09393
Type Targeted MutationCartagena
Species Mus musculus
Strain name B6-Kcnj11<tm2Sse>
Former Common name Kir6.2-flox
H-2 Haplotype No Data
Background strain C57BL/6JJcl
Appearance
1 Appearance No Data
Genotype No Data
Strain description No Data
Health Report
Gene Details
Promoter No Data
1 Symbol Kcnj11
Symbol name potassium inwardly rectifying channel, subfamily J, member 11
Chromosome 7
Common name Kir6.2
Symbol description No Data
2 Symbol Frt
Symbol name yeast FRT (flippase recombination target) site
Chromosome 7
Common name No Data
Symbol description No Data
3 Symbol GH
Symbol name Growth hormone polyA (Bovine)
Chromosome 7
Common name No Data
Symbol description No Data
4 Symbol loxP
Symbol name phage P1 loxP
Chromosome 7
Common name No Data
Symbol description No Data
Promoter mouse phosphoglycerate kinase promoter (PGK promoter)
5 Symbol neo
Symbol name neomycin resistance gene (E. coli)
Chromosome 7
Common name No Data
Symbol description No Data
References No Data

Research applications Cre/loxP system,
Endocrine Deficiency Research,
FLP/frt system,
Neurobiology Research
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form.
Additional information
1 No Data
2 Genotyping protocol <PCR>
Depositor Seino, Susumu (Kobe University) Seino, Susumu
Strain Status /
Availability
(Expected delivery)


Sperm
Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months

RBRC09669, C57BL/6-Slc17a7<tm1.1Sse>

RBRC No. RBRC09669
Type Targeted MutationCartagena
Species Mus musculus
Strain name C57BL/6-Slc17a7<tm1.1Sse>
Former Common name VGLUT1-flox
H-2 Haplotype No Data
ES cell line RENKA [C57BL/6NCrlCrlj]
Background strain C57BL/6JJcl
Appearance
1 Appearance No Data
Genotype No Data
Strain development Developed by Norihide Yokoi and Susumu Seino, Kobe University Graduate School of Medicine.
RENKA ES cell line (C57BL/6N) was used. Mice were maintained in C57BL/6J.
Strain description Floxed VGLUT1 (Slc17a7) mice. Two loxP sites are flanking the exon 2 encoding the first transmembrane domain of the VGLUT1.
Colony maintenance Heterozygote x Wild-type [or Crossing to C57BL/6JJcl]
Health Report No Data
Gene Details
Promoter No Data
1 Symbol Frt
Symbol name yeast FRT (flippase recombination target) site
Chromosome 7
Common name No Data
Symbol description No Data
2 Symbol Slc17a7
Symbol name solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7
Chromosome 7
Common name No Data
Symbol description No Data
3 Symbol loxP
Symbol name phage P1 loxP
Chromosome 7
Common name No Data
Symbol description No Data
References No Data

Research applications Cre/loxP system,
FLP/frt system
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form.
Additional information
1 No Data
2 Genotyping protocol <PCR>
Depositor Seino, Susumu (Kobe University) Seino, Susumu
Strain Status /
Availability
(Expected delivery)


Sperm
Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months