RBRC02280, B6.129S4-Ephb6<tm1Tom>

RBRC No. RBRC02280
Type Targeted MutationCartagena wks
Species Mus musculus
Strain name B6.129S4-Ephb6<tm1Tom>
Former Common name EphB6 knock-out mouse
H-2 Haplotype No Data
ES cell line J1 [129S4/SvJae]
Background strain No Data
Appearance
1 Appearance black
Genotype a/a B/B C/C
Strain development Developed by Dr. Toshimitsu Matsui, Kobe University in 2002.
Strain description B6.129S4-Ephb6<tm1Tom>. EphB6, Eph receptor B6, is a member of the largest family of receptor protein kinases. Homozygous mutant mice developed normally and fertile, but T cell responses in them were compromised. This strain is useful for elucidating the EphB6 gene function.
Colony maintenance Sibling Mating (Homozygote x Homozygote)
Health Report
Gene Details
Promoter No Data
1 Symbol Ephb6
Symbol name Eph receptor B6
Chromosome 6
Common name Cekl, Mep
Symbol description No Data
2 Symbol loxP
Symbol name phage P1 loxP
Chromosome 6
Common name No Data
Symbol description No Data
Promoter mouse phosphoglycerate kinase promoter (PGK promoter)
3 Symbol neo
Symbol name neomycin resistance gene (E. coli)
Chromosome 6
Common name neo; neomycin;
Symbol description No Data
References Biochem Biophys Res Commun. 2002 Oct 18;298(1):87-94.

Developmental expression of EphB6 in the thymus: lessons from EphB6 knockout mice.
Research applications Cancer Research,
Cell Biology Research,
Cre/loxP system,
Immunology and Inflammation Research,
Neurobiology Research
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
Biochem. Biophys. Res. Commun., 298, 87-94 (2002).
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Shimoyama M. et al. Biochem Biophys Res Commun 298; 87-94: 2002
The RECIPIENT of BIOLOGICAL RESOURCE must obtain a prior written consent on use of it from the DEPOSITOR/DEVELOPER. The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use or publication with the results from the use of the BIOLOGICAL RESOURCE. However, it may not be a collaboration if the research interest is out of field of the DEPOSITOR.
Additional information
1 Lab HP (Japanese)
2 Genotyping protocol <PCR>
Depositor Matsui, Toshimitsu (Kobe University Graduate School of Medicine) Matsui, Toshimitsu
Strain Status /
Availability
(Expected delivery)


Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

Sperm
Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months

RBRC02289, B6.129S4-Cckbr<tm1Tom>

RBRC No. RBRC02289
Type Targeted MutationCartagena
Species Mus musculus
Strain name B6.129S4-Cckbr<tm1Tom>
Former Common name CCKBR knock-out mice
H-2 Haplotype No Data
ES cell line J1 [129S4/SvJae]
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain description No Data
Health Report
Gene Details
Promoter No Data
1 Symbol Cckbr
Symbol name cholecystokinin B receptor
Chromosome 7
Common name CCK-B/gastrin receptor, CCK2/gastrin, CCK2R, CCKR-2
Symbol description No Data
2 Symbol lacZ
Symbol name beta-galactosidase (E. coli)
Chromosome 7
Common name No Data
Symbol description E. coli beta galactosidase
Promoter mouse phosphoglycerate kinase promoter (PGK promoter)
3 Symbol neo
Symbol name neomycin resistance gene (E. coli)
Chromosome 7
Common name neo; neomycin;
Symbol description No Data
References

Research applications Fluorescent Proteins/lacZ System,
Internal/Organ Research,
Metabolism Research,
Neurobiology Research
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The RECIPIENT of BIOLOGICAL RESOURCE must obtain a prior written consent on use of it from the DEPOSITOR/DEVELOPER. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. Proc. Natl. Acad. Sci. USA, 93, 11825-11830 (1996). The RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use or publication with the results from the use of the BIOLOGICAL RESOURCE. However, it may not be a collaboration if the research interest is out of field of the DEPOSITOR.
Additional information
1 Lab HP (Japanese)
2 Genotyping protocol <PCR>
Depositor Matsui, Toshimitsu (Kobe University Graduate School of Medicine) Matsui, Toshimitsu
Strain Status /
Availability
(Expected delivery)


Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

Sperm
Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months

RBRC02446, B6.Cg-Zc3h12d<tm1Tom>

RBRC No. RBRC02446
Type Targeted Mutation CongenicCartagena
Species Mus musculus
Strain name B6.Cg-Zc3h12d<tm1Tom>
Former Common name No Data
H-2 Haplotype No Data
Background strain C57BL/6JJcl
Appearance
1 Appearance No Data
Genotype No Data
Strain description No Data
Health Report No Data
Gene Details
Promoter No Data
1 Symbol Zc3h12d
Symbol name zinc finger CCCH type containing 12D
Chromosome 10
Common name D730019B10Rik
Symbol description No Data
Promoter mouse phosphoglycerate kinase promoter (PGK promoter)
2 Symbol neo
Symbol name neomycin resistance gene (E. coli)
Chromosome 10
Common name neo; neomycin;
Symbol description No Data
References Br J Haematol. 2007 Oct;139(1):161-3.

Deregulation of a possible tumour suppressor gene, ZC3H12D, by translocation of IGK@ in transformed follicular lymphoma with t(2;6)(p12;q25).
Research applications Cell Biology Research
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR.
The RECIPIENT agrees to use this BIOLOGICAL RESOURCE as a collaboration with the DEPOSITOR.
Additional information
1 Genetic Background
2 Lab HP (Japanese)
3 Genotyping protocol <PCR>
Depositor Matsui, Toshimitsu (Kobe University Graduate School of Medicine) Matsui, Toshimitsu
Strain Status /
Availability
(Expected delivery)


Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

Sperm
Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months