RBRC02213, B6;129P2-Cyp26c1<tm1.1Keya>

RBRC No. RBRC02213
Type Targeted MutationCartagena
Species Mus musculus
Strain name B6;129P2-Cyp26c1<tm1.1Keya>
Former Common name Cyp26c1 null, B6;129P2-Cyp26c1<tm1Hmd>
H-2 Haplotype No Data
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain description No Data
Health Report
Gene Details
Promoter No Data
1 Symbol Cyp26c1
Symbol name cytochrome P450, family 26, subfamily c, polypeptide 1
Chromosome 19
Common name EG546726
Symbol description No Data
2 Symbol loxP
Symbol name phage P1 loxP
Chromosome 19
Common name No Data
Symbol description No Data
References Dev Biol. 2006 Sep 30;.

CYP26A1 and CYP26C1 cooperatively regulate anterior-posterior patterning of the developing brain and the production of migratory cranial neural crest cells in the mouse.
Research applications Cre/loxP system,
Developmental Biology Research
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR.
The RECIPIENT of BIOLOGICAL RESOURCE must obtain a prior written consent on use of it from the DEPOSITOR/DEVELOPER.
Additional information
1 No Data
2 Genotyping protocol <PCR>
Depositor Hamada, Hiroshi (RIKEN Center for Developmental Biology) Hamada, Hiroshi
Strain Status /
Availability
(Expected delivery)


Sperm
Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months

RBRC03103, B6;129-Pitx2<tm1Hmd>

RBRC No. RBRC03103
Type Targeted MutationCartagena wks
Species Mus musculus
Strain name B6;129-Pitx2<tm1Hmd>
Former Common name Pitx2 delta ASE
H-2 Haplotype No Data
ES cell line R1 [(129X1/SvJ x 129S1/Sv)F1-Kitl<+>]
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain description No Data
Health Report
Gene Details
Promoter No Data
1 Symbol Pitx2
Symbol name paired-like homeodomain transcription factor 2
Chromosome 3
Common name paired-like homeodomain transcription factor 2
Symbol description No Data
2 Symbol loxP
Symbol name phage P1 loxP
Chromosome No Data
Common name No Data
Symbol description No Data
References Development. 2006 Aug;133(15):3015-25.

Conserved regulation and role of Pitx2 in situs-specific morphogenesis of visceral organs.
Research applications No Data
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The RECIPIENT of BIOLOGICAL RESOURCE must obtain a prior written consent on use of it from the DEPOSITOR/DEVELOPER.
Additional information
1 No Data
2 Genotyping protocol <PCR>
Depositor Hamada, Hiroshi (RIKEN Center for Developmental Biology) Hamada, Hiroshi
Strain Status /
Availability
(Expected delivery)


Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

Sperm
Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months

RBRC04333, B6;B6129-Cyp26b1<tm2Hmd>

RBRC No. RBRC04333
Type Targeted MutationCartagena
Species Mus musculus
Strain name B6;B6129-Cyp26b1<tm2Hmd>
Former Common name Cyp26b1 flox
H-2 Haplotype No Data
ES cell line G4 [(129S6/SvEvTac x C57BL/6NCr)F1]
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain description No Data
Health Report
Gene Details
Promoter No Data
1 Symbol Cyp26b1
Symbol name cytochrome P450, family 26, subfamily b, polypeptide 1
Chromosome 6
Common name No Data
Symbol description No Data
2 Symbol Frt
Symbol name yeast FRT (flippase recombination target) site
Chromosome 6
Common name No Data
Symbol description No Data
3 Symbol loxP
Symbol name phage P1 loxP
Chromosome 6
Common name No Data
Symbol description No Data
References No Data

Research applications Cre/loxP system,
FLP/frt system
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The RECIPIENT of BIOLOGICAL RESOURCE must obtain a prior written consent on use of it from the DEPOSITOR/DEVELOPER.
Additional information
1 No Data
2 Genotyping protocol <PCR>
Depositor Hamada, Hiroshi (RIKEN Center for Developmental Biology) Hamada, Hiroshi
Strain Status /
Availability
(Expected delivery)


Sperm
Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months

RBRC04852, B6C3(129)-Tg(NDE-hsp-Smad3DN,lacZ)1Hmd

RBRC No. RBRC04852
Type TransgeneCartagena
Species Mus musculus
Strain name B6C3(129)-Tg(NDE-hsp-Smad3DN,lacZ)1Hmd
Former Common name NDE-dnSmad3-1Z(1)
H-2 Haplotype No Data
Background strain Jcl:B6C3F1
Appearance
1 Appearance No Data
Genotype No Data
Strain development Developed by Aiko Kawasumi and Hiroshi Hamada, Graduate School of Frontier Biosciences, Osaka University in 2009 The transgene was injected into the pronuclei of (C57BL/6 x C3H) F1 fertelized eggs. C57BL/6, C3H and 129 mixed background.
Strain description No Data
Colony maintenance Carrier x Noncarrier [or Crossing to Jcl:B6C3F1]
Health Report
Gene Details
Promoter No Data
1 Symbol IRES
Symbol name internal ribosomal entry site (EMCV)
Chromosome UN
Common name internal ribosomal entry site from EMCV
Symbol description No Data
2 Symbol lacZ
Symbol name beta-galactosidase (E. coli)
Chromosome UN
Common name No Data
Symbol description E. coli beta galactosidase
Promoter mouse hsp promoter
3 Symbol Smad3
Symbol name SMAD family member 3
Chromosome UN
Common name No Data
Symbol description No Data
References

Research applications Fluorescent Proteins/lacZ System
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The RECIPIENT of BIOLOGICAL RESOURCE must obtain a prior written consent on use of it from the DEPOSITOR/DEVELOPER.
Additional information
1 No Data
Depositor Hamada, Hiroshi (RIKEN Center for Developmental Biology) Hamada, Hiroshi
Strain Status /
Availability
(Expected delivery)


Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

Sperm
Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months

RBRC05474, B6.Cg-Tg(Foxj1-Cluap1,lacZ)14Hmd

RBRC No. RBRC05474
Type TransgeneCartagena
Species Mus musculus
Strain name B6.Cg-Tg(Foxj1-Cluap1,lacZ)14Hmd
Former Common name FxJ1-1.1 Qilin-lacZ (14), B6-Foxj1-Qilin/LacZ Tg#14
H-2 Haplotype No Data
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain development Developed by Hiroshi Hamada, Graduate School of Frontier Biosciences, Osaka University. 1.1 kb segment containing human FoxJ1 promoter and Qilin cDNA-IRES LacZ genes were injected into the pronuclei of ((C57BL/6 x BALB/c)F1 x B6129-Qilin<tm1.1Hmd>)F1 fertilized eggs. C57BL/6 and 129 mixed background.
Strain description Transgene specifically express Cluap1 (Qilin) and LacZ reporter in pit cells of embryonic node. Tg expression can be monitored by X-gal staining.
Colony maintenance Carrier x Noncarrier [C57BL/6JJcl]
Health Report No Data
Gene Details
Promoter No Data
1 Symbol IRES
Symbol name internal ribosomal entry site (EMCV)
Chromosome UN
Common name No Data
Symbol description No Data
2 Symbol lacZ
Symbol name beta-galactosidase (E. coli)
Chromosome UN
Common name No Data
Symbol description No Data
Promoter human Foxj1 promoter
3 Symbol Cluap1
Symbol name clusterin associated protein 1
Chromosome UN
Common name Qilin
Symbol description No Data
References

Research applications Fluorescent Proteins/lacZ System
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The RECIPIENT of BIOLOGICAL RESOURCE must obtain a prior written consent on use of it from the DEPOSITOR/DEVELOPER.
Additional information
1 No Data
Depositor Hamada, Hiroshi (RIKEN Center for Developmental Biology) Hamada, Hiroshi
Strain Status /
Availability
(Expected delivery)


Preparing for distribution
Preparing for distribution
(Please note that it may take more than 6 months to make arrangements to distribute.)

Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

RBRC06542, B6.Cg-Lrrc6<tm1.2Hmd>

RBRC No. RBRC06542
Type Targeted MutationCartagena
Species Mus musculus
Strain name B6.Cg-Lrrc6<tm1.2Hmd>
Former Common name Lrrc6 null, B6-Lrrc6 KO
H-2 Haplotype No Data
ES cell line G4 [(129S6/SvEvTac x C57BL/6NCr)F1]
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain development Developed by Katsura Minegishi and Hiroshi Hamada, Graduate School of Frontier Biosciences, Osaka University in 2010. G4 ES cells derived from (129 x C57BL/6)F1 were used to generate the mutant mice. Flanked Exon 1 was removed by crossing with CAG-Cre mice (B6/129 background). C57BL/6 and 129 mixed background.
Strain description Exon 1 of Lrrc6 gene was removed.
Colony maintenance Heterozygote x Wild-type [C57BL/6JJcl]
Health Report
Gene Details
Promoter No Data
1 Symbol Lrrc6
Symbol name leucine rich repeat containing 6 (testis)
Chromosome 15
Common name No Data
Symbol description No Data
2 Symbol loxP
Symbol name phage P1 loxP
Chromosome 15
Common name No Data
Symbol description No Data
References No Data

Research applications Cre/loxP system
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR/DEVELOPER.
RECIPIENT which wants to use the BIOLOGICAL RESOURCE for the purpose other than education or not-for-profit research is requested to enter into a Material Transfer Agreement with Osaka University.
Additional information
1 No Data
2 Genotyping protocol <PCR>
Depositor Hamada, Hiroshi (RIKEN Center for Developmental Biology) Hamada, Hiroshi
Strain Status /
Availability
(Expected delivery)


Preparing for distribution
Preparing for distribution
(Please note that it may take more than 6 months to make arrangements to distribute.)

Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

Sperm
Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months

Live
Live mouse :

RBRC09511, B6 129-Rsph4a<tm1.1Hmd>

RBRC No. RBRC09511
Type Targeted MutationCartagena
Species Mus musculus
Strain name B6 129-Rsph4a<tm1.1Hmd>
Former Common name No Data
H-2 Haplotype No Data
ES cell line G4 [(129S6/SvEvTac x C57BL/6NCr)F1]
Background strain C57BL/6JJcl
Appearance
1 Appearance No Data
Genotype No Data
Strain description No Data
Health Report No Data
Gene Details
Promoter No Data
1 Symbol Rsph4a
Symbol name radial spoke head 4 homolog A (Chlamydomonas)
Chromosome 10
Common name No Data
Symbol description No Data
2 Symbol loxP
Symbol name phage P1 loxP
Chromosome 10
Common name No Data
Symbol description No Data
References No Data

Research applications Cre/loxP system
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The RECIPIENT of BIOLOGICAL RESOURCE must obtain a prior written consent on use of it from the DEPOSITOR/DEVELOPER. RECIPIENT which wants to use the BIOLOGICAL RESOURCE for the purpose other than education or not-for- profit research is requested to enter into a Material Transfer Agreement with Osaka University.
Additional information
1 No Data
Depositor Hamada, Hiroshi (RIKEN Center for Developmental Biology) Hamada, Hiroshi
Strain Status /
Availability
(Expected delivery)


Preparing for distribution
Preparing for distribution
(Please note that it may take more than 6 months to make arrangements to distribute.)

Sperm
Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months

RBRC02214, B6;129P2-Gfra3<tm1Hmd>

RBRC No. RBRC02214
Type Targeted MutationCartagena wks
Species Mus musculus
Strain name B6;129P2-Gfra3<tm1Hmd>
Former Common name Gfra3 KO
H-2 Haplotype No Data
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain description No Data
Health Report
Gene Details
Promoter No Data
1 Symbol Gfra3
Symbol name glial cell line derived neurotrophic factor family receptor alpha 3
Chromosome 18
Common name No Data
Symbol description No Data
Promoter SV40 and herpes simplex virus thymidine kinase promoter (HSV tk promoter)
2 Symbol neo
Symbol name neomycin resistance gene (E. coli)
Chromosome 18
Common name neo; neomycin;
Symbol description No Data
References

Research applications Developmental Biology Research,
Neurobiology Research
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR.
The RECIPIENT of BIOLOGICAL RESOURCE must obtain a prior written consent on use of it from the DEPOSITOR/DEVELOPER.
Additional information
1 No Data
2 Genotyping protocol <PCR>
Depositor Hamada, Hiroshi (RIKEN Center for Developmental Biology) Hamada, Hiroshi
Strain Status /
Availability
(Expected delivery)


Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

Sperm
Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months

RBRC03104, B6C3-Tg(NodalASE-hsp68-lacZ)82Hmd

RBRC No. RBRC03104
Type TransgeneCartagena
Species Mus musculus
Strain name B6C3-Tg(NodalASE-hsp68-lacZ)82Hmd
Former Common name Nodal ASE-LacZ(82)
H-2 Haplotype No Data
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain description No Data
Health Report
Gene Details
Promoter No Data
1 Symbol Nodal
Symbol name nodal
Chromosome 10
Common name No Data
Symbol description No Data
Promoter mouse hsp68 promoter
2 Symbol lacZ
Symbol name beta-galactosidase (E. coli)
Chromosome No Data
Common name No Data
Symbol description E. coli beta galactosidase
References Genes Dev. 1999 Jun 15;13(12):1589-600.

Determination of left/right asymmetric expression of nodal by a left side-specific enhancer with sequence similarity to a lefty-2 enhancer.
Research applications No Data
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The RECIPIENT of BIOLOGICAL RESOURCE must obtain a prior written consent on use of it from the DEPOSITOR/DEVELOPER.
Additional information
1 No Data
2 Genotyping protocol <PCR>
Depositor Hamada, Hiroshi (RIKEN Center for Developmental Biology) Hamada, Hiroshi
Strain Status /
Availability
(Expected delivery)


Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

Sperm
Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months

RBRC04334, B6;129-Cyp26a1<tm1.1Hmd> Cyp26c1<tm1Hmd>

RBRC No. RBRC04334
Type Targeted MutationCartagena
Species Mus musculus
Strain name B6;129-Cyp26a1<tm1.1Hmd> Cyp26c1<tm1Hmd>
Former Common name No Data
H-2 Haplotype No Data
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain description No Data
Health Report
Gene Details
Promoter No Data
1 Symbol Cyp26a1
Symbol name cytochrome P450, family 26, subfamily a, polypeptide 1
Chromosome 19
Common name No Data
Symbol description No Data
2 Symbol Cyp26c1
Symbol name cytochrome P450, family 26, subfamily c, polypeptide 1
Chromosome 19
Common name No Data
Symbol description No Data
3 Symbol Frt
Symbol name yeast FRT (flippase recombination target) site
Chromosome No Data
Common name No Data
Symbol description No Data
4 Symbol loxP
Symbol name phage P1 loxP
Chromosome No Data
Common name No Data
Symbol description No Data
References Dev Biol. 2006 Sep 30;.

CYP26A1 and CYP26C1 cooperatively regulate anterior-posterior patterning of the developing brain and the production of migratory cranial neural crest cells in the mouse.
Research applications No Data
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The RECIPIENT of BIOLOGICAL RESOURCE must obtain a prior written consent on use of it from the DEPOSITOR/DEVELOPER.
Additional information
1 No Data
Depositor Hamada, Hiroshi (RIKEN Center for Developmental Biology) Hamada, Hiroshi
Strain Status /
Availability
(Expected delivery)


Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

Sperm
Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months