RBRC09756, C57BL/6N-Ftl1<em2Rbrc>

RBRC No. RBRC09756
Type CRISPR/Cas9
Species Mus musculus
Strain name C57BL/6N-Ftl1<em2Rbrc>
Former Common name No Data
H-2 Haplotype No Data
Background strain C57BL/6NJcl
Appearance
1 Appearance No Data
Genotype No Data
Strain description No Data
Health Report
Gene Details
Promoter No Data
1 Symbol Ftl1
Symbol name ferritin light polypeptide 1
Chromosome 7
Common name No Data
Symbol description No Data
References No Data

Research applications No Data
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The RECIPIENT should acknowledge RIKEN BRC and the International Mouse Phenotyping Consortium for creating and providing of the knockout mice.
Additional information
1 No Data
2 Genotyping protocol <PCR>
Depositor RIKEN, BioResource Center
Strain Status /
Availability
(Expected delivery)


Sperm
Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months

RBRC10034, C57BL/6N-H2-M3<em1Rbrc>

RBRC No. RBRC10034
Type CRISPR/Cas9
Species Mus musculus
Strain name C57BL/6N-H2-M3<em1Rbrc>
Former Common name No Data
H-2 Haplotype No Data
Background strain C57BL/6NJcl
Appearance
1 Appearance No Data
Genotype No Data
Strain description No Data
Health Report
Gene Details
Promoter No Data
1 Symbol H2-M3
Symbol name histocompatibility 2, M region locus 3
Chromosome 17
Common name No Data
Symbol description No Data
References No Data

Research applications No Data
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The RECIPIENT should acknowledge RIKEN BRC and the International Mouse Phenotyping Consortium for creating and providing of the knockout mice.
Additional information
1 No Data
Depositor RIKEN, BioResource Center
Strain Status /
Availability
(Expected delivery)


Sperm
Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months

RBRC00193, GRS.Cg-Tnc<tm1Sia>/Rbrc

RBRC No. RBRC00193
Type Targeted MutationCartagena ♀
Species Mus musculus
Strain name GRS.Cg-Tnc<tm1Sia>/Rbrc
Former Common name GRS/A-TgH(Tnc), GR-TNKO
H-2 Haplotype No Data
ES cell line TT2 [(C57BL/6NCrlj x CBA/JNCrlj)F1]
Donor strain B6.CB-Tnctm1
Background strain GRS/A
Appearance
1 Appearance albino
Genotype a/a, c/c
Strain development The original tenascin deficient mice with mixed genetic background was reported to develop normally without tenascin. To clarify the biological function of tenascin-C in vivo, several congenic strains with inbred background have been developed by Dr. Kusakabe M, Cell Biology Laboratory, Life Science Tsukuba Research Center, RIKEN since 1992.
The tenascin-deficient congenic strains were thus developed by successive backcrossing into A, BALB/cA, C57BL/6N, C3H/HeN, and GRS/A.
Strain description This strain is useful to study the biological function of extracellular matrix tenascin-C in vivo, espacially in the field of tumor development, tumor metastasis, wound healing, tissue regeneration, angiogenesis, tissue interaction etc. Background strain, GRS/A have a high incidence of mammary tumours which are highly hormone-responsive in breeding females.
Health Report No Data
Gene Details
Promoter No Data
1 Symbol Tnc
Symbol name tenascin C
Chromosome 4
Common name Tnc; tenascin C, Hxb, Ten, TN-C, AI528729
Symbol description No Data
2 Symbol lacZ
Symbol name beta-galactosidase (E. coli)
Chromosome 4
Common name No Data
Symbol description E. coli beta galactosidase
Promoter mouse phosphoglycerate kinase promoter (PGK promoter)
3 Symbol neo
Symbol name neomycin resistance gene (E. coli)
Chromosome 4
Common name neo; neomycin;
Symbol description No Data
References Am J Pathol. 1998 May;152(5):1237-45.
Biochem Biophys Res Commun. 1996 Apr 5;221(1):151-6.
Biochem Biophys Res Commun. 1997 Feb 13;231(2):356-9.
Biochem Biophys Res Commun. 2002 Feb 1;290(4):1220-7.
Exp Mol Pathol. 2002 Jun;72(3):186-95.
Gene. 1991 Aug 15;104(2):177-85.
Genes Dev. 1992 Oct;6(10):1821-31.
Invest Ophthalmol Vis Sci. 1999 May;40(6):1071-80.
J Comp Neurol. 2001 Feb 19;430(4):485-500.
J Invest Dermatol. 1998 Dec;111(6):930-5.
J Neurosci. 1995 Mar;15(3 Pt 1):1971-83.
Perspect Dev Neurobiol 1994;2(1):111-16.

Tenascin-C promotes healing of Habu-snake venom-induced glomerulonephritis: studies in knockout congenic mice and in culture.
Tenascin-C promotes healing of Habu-snake venom-induced glomerulonephritis: studies in knockout congenic mice and in culture.
Tenascin-C promotes healing of Habu-snake venom-induced glomerulonephritis: studies in knockout congenic mice and in culture.
Tenascin-C promotes healing of Habu-snake venom-induced glomerulonephritis: studies in knockout congenic mice and in culture.
Tenascin-C promotes healing of Habu-snake venom-induced glomerulonephritis: studies in knockout congenic mice and in culture.
Tenascin-C promotes healing of Habu-snake venom-induced glomerulonephritis: studies in knockout congenic mice and in culture.
Tenascin-C promotes healing of Habu-snake venom-induced glomerulonephritis: studies in knockout congenic mice and in culture.
Tenascin-C promotes healing of Habu-snake venom-induced glomerulonephritis: studies in knockout congenic mice and in culture.
Tenascin-C promotes healing of Habu-snake venom-induced glomerulonephritis: studies in knockout congenic mice and in culture.
Tenascin-C promotes healing of Habu-snake venom-induced glomerulonephritis: studies in knockout congenic mice and in culture.
Tenascin-C promotes healing of Habu-snake venom-induced glomerulonephritis: studies in knockout congenic mice and in culture.
Tenascin-C promotes healing of Habu-snake venom-induced glomerulonephritis: studies in knockout congenic mice and in culture.
Research applications No Data
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
Am. J. Pathol., 152, 1237-1245 (1998). J. Invest. Dermatol., 111, 930-935 (1998). Invest. Ophthalmol. Visual. Sci., 40, 1071-1080 (1999).
Additional information
1 No Data
2 Genotyping protocol <PCR>
Depositor RIKEN, BioResource Center
Strain Status /
Availability
(Expected delivery)


Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

RBRC01626, MSM.B6-Tg(CAG-EGFP)C14-Y01-FM131Osb/Rbrc

RBRC No. RBRC01626
Type TransgeneCartagena
Species Mus musculus molossinus
Strain name MSM.B6-Tg(CAG-EGFP)C14-Y01-FM131Osb/Rbrc
Former Common name No Data
H-2 Haplotype No Data
Donor strain C57BL/6-Tg(CAG-EGFP)C14-Y01-FM131Osb/Rbrc
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain description No Data
Health Report
Gene Details
Promoter CAG promoter (CMV-IE enhancer, chicken beta-actin promoter, rabbit beta-globin genomic DNA)
1 Symbol GFP
Symbol name Green Fluorescent Protein (Jellyfish)
Chromosome 14
Common name No Data
Symbol description No Data
References No Data

Research applications No Data
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the Department of Experimental Genome Research, Research Institute for Microbial Diseases, Osaka University. The RECIPIENT which wants to use the BIOLOGICAL RESOURCE for the purpose other than education or not-for-profit research is requested to enter into a Material Transfer Agreement with Osaka University. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the Department of Experimental Genome Research. The RECIPIENT which wants to use the BIOLOGICAL RESOURCE even after five years must obtain a written consent from the DEPOSITOR again.
Additional information
1 GFP Transfer License (Japanese / English)
Please fill in the Schedule A, and submit two signed copies to us together with two signed copies of RIKEN BRC’s MTA. Please also read Schedule B.
2 Mouse of the Month Feb 2012
Genetic Background
Depositor RIKEN, BioResource Center
Strain Status /
Availability
(Expected delivery)


Preparing for distribution
Preparing for distribution
(Please note that it may take more than 6 months to make arrangements to distribute.)

Sperm
Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months

RBRC04202, C57BL/6N-Tg(CAG-KO,Halo/GFP)477-5Sasa/Rbrc

RBRC No. RBRC04202
Type TransgeneCartagena
Species Mus musculus
Strain name C57BL/6N-Tg(CAG-KO,Halo/GFP)477-5Sasa/Rbrc
Former Common name No Data
H-2 Haplotype No Data
Background strain C57BL/6NCrlCrlj
Appearance
1 Appearance No Data
Genotype No Data
Strain development Developed by National Institute for Basic Biology and RIKEN BioResource Center in 2010. C57BL/6N background.
Strain description Optogenetic transgenic mice. A transgenic construct containing CAG promoter, a loxP-KO (Kusabira Orange)-STOP-loxP sequence and a Halo (halorhodopsin)-GFP fusion cDNA was microinjected into C57BL/6NCrlCrlj fertilized eggs. Expression of KO and Halo/GFP has not been examined yet. Users are encouraged to test the expression pattern and feed back the data for the research community.
Colony maintenance Carrier x Noncarrier [C57BL/6NCrlCrlj]. Hemizygous Tg mice are viable and fertile (viability and fertility of homozygotes are unknown).
Health Report
BRC facility Health Report in the last year and a half

Examination Date Room Rack
Sep 3, 2012 2-検 B
Jul 2, 2012 2-検 B
May 7, 2012 2-検 B
Mar 5, 2012 2-検 B
Jan 10, 2012 2-検 B
Nov 7, 2011 2-検 B
Sep 5, 2011 2-検 B
Jul 4, 2011 2-検 B

Gene Details
Promoter No Data
1 Symbol GFP
Symbol name Green Fluorescent Protein (Jellyfish)
Chromosome No Data
Common name No Data
Symbol description No Data
2 Symbol KO
Symbol name Kusabira Orange
Chromosome No Data
Common name No Data
Symbol description No Data
References No Data

Research applications Fluorescent Proteins/lacZ System
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to Dr. Toshikuni Sasaoka, National Institute for Basic Biology and RIKEN BioResource Center is requested. In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested. (will be announced) The availability of the BIOLOGICAL RESOURCE is limited to a RECIPIENT of a not-for profit institution for a not-for-profit research. For use of the BIOLOGICAL RESOURCE by a for-profit institution, the RECIPIENT must reach agreement on terms and conditions of use of it with DEPOSITOR and must obtain a prior written consent from the DEPOSITOR. RECIPIENT must contact the DEPOSITOR in the case of application for any patents or commercial use based on the results from the use of the BIOLOGICAL RESOURCE.
Additional information
1 GFP Transfer License (Japanese / English)
Please fill in the Schedule A, and submit two signed copies to us together with two signed copies of RIKEN BRC’s MTA. Please also read Schedule B.
Depositor RIKEN, BioResource Center
Strain Status /
Availability
(Expected delivery)


Sperm
Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months

RBRC05432, C57BL/6N-D1Pas1<tm1(KOMP)Vlcg>/D4

RBRC No. RBRC05432
Type Targeted MutationCartagena
Species Mus musculus
Strain name C57BL/6N-D1Pas1<tm1(KOMP)Vlcg>/D4
Former Common name B6-D1Pas1 KO#D4
H-2 Haplotype No Data
ES cell line VGB6 [C57BL/6NTac]
Background strain C57BL/6NTac
Appearance
1 Appearance No Data
Genotype No Data
Strain description No Data
Health Report
Gene Details
Promoter No Data
1 Symbol D1Pas1
Symbol name DNA segment, Chr 1, Pasteur Institute 1
Chromosome 1
Common name No Data
Symbol description No Data
2 Symbol lacZ
Symbol name beta-galactosidase (E. coli)
Chromosome 1
Common name No Data
Symbol description No Data
3 Symbol loxP
Symbol name phage P1 loxP
Chromosome 1
Common name No Data
Symbol description No Data
4 Symbol neo
Symbol name neomycin resistance gene (E. coli)
Chromosome 1
Common name No Data
Symbol description No Data
References No Data

Research applications Cre/loxP system,
Fluorescent Proteins/lacZ System
Specific Term and Conditions For inquiries please mail us at animal@brc.riken.jp.
Additional information
1 No Data
2 Genotyping protocol <PCR>
Depositor RIKEN, BioResource Center
Strain Status /
Availability
(Expected delivery)


Sperm
Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months

Live
Live mouse :
BRC mice in Publications
Title Journal
(PMID)
Author
Mouse D1Pas1, a DEAD-box RNA helicase, is required for the completion of first meiotic prophase in male germ cells. Biochem. Biophys. Res. Commun. (2016).(27473657)
Inoue H, Ogonuki N, Hirose M, Hatanaka Y, Matoba S, Chuma S, Kobayashi K, Wakana S, Noguchi J, Inoue K, Tanemura K, Ogura A.

RBRC05676, C57BL/6N-Adcyap1r1<tm1a(KOMP)Wtsi>/B07

RBRC No. RBRC05676
Type Targeted MutationCartagena
Species Mus musculus
Strain name C57BL/6N-Adcyap1r1<tm1a(KOMP)Wtsi>/B07
Former Common name No Data
H-2 Haplotype No Data
ES cell line JM8A3.N1 [C57BL/6N-A]
Background strain C57BL/6NTac
Appearance
1 Appearance No Data
Genotype No Data
Strain description No Data
Health Report No Data
Gene Details
Promoter No Data
1 Symbol Adcyap1r1
Symbol name adenylate cyclase activating polypeptide 1 receptor 1
Chromosome 6
Common name No Data
Symbol description No Data
References No Data

Research applications No Data
Specific Term and Conditions For inquiries please mail us at animal@brc.riken.jp.
Additional information
1 No Data
Depositor RIKEN, BioResource Center
Strain Status /
Availability
(Expected delivery)


Sperm
Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months

RBRC06184, C57BL/6N-Galp<tm1b(EUCOMM)Wtsi>/E05

RBRC No. RBRC06184
Type Targeted MutationCartagena
Species Mus musculus
Strain name C57BL/6N-Galp<tm1b(EUCOMM)Wtsi>/E05
Former Common name No Data
H-2 Haplotype No Data
ES cell line JM8A1.N3 [C57BL/6N-A]
Background strain C57BL/6NTac
Appearance
1 Appearance No Data
Genotype No Data
Strain description No Data
Health Report No Data
Gene Details
Promoter No Data
1 Symbol Galp
Symbol name galanin-like peptide
Chromosome 7
Common name No Data
Symbol description No Data
References No Data

Research applications No Data
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The RECIPIENT should acknowledge the EUCOMM, RIKEN BRC and the International Mouse Phenotyping Consortium as the original creator of the targeted mouse ES cells and the provider of the knockout mice, respectively.
Additional information
1 No Data
Depositor RIKEN, BioResource Center
Strain Status /
Availability
(Expected delivery)


Sperm
Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months

RBRC06345, C57BL/6N-Ube2g1<tm1b(EUCOMM)Hmgu>/B02

RBRC No. RBRC06345
Type Targeted MutationCartagena
Species Mus musculus
Strain name C57BL/6N-Ube2g1<tm1b(EUCOMM)Hmgu>/B02
Former Common name No Data
H-2 Haplotype No Data
ES cell line JM8A3.N1 [C57BL/6N-A]
Background strain C57BL/6NTac
Appearance
1 Appearance No Data
Genotype No Data
Strain description No Data
Health Report No Data
Gene Details
Promoter No Data
1 Symbol Ube2g1
Symbol name ubiquitin-conjugating enzyme E2G 1
Chromosome 11
Common name No Data
Symbol description No Data
References No Data

Research applications No Data
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The RECIPIENT should acknowledge the EUCOMM, RIKEN BRC and the International Mouse Phenotyping Consortium as the original creator of the targeted mouse ES cells and the provider of the knockout mice, respectively.
Additional information
1 No Data
2 Genotyping protocol <PCR>
Depositor RIKEN, BioResource Center
Strain Status /
Availability
(Expected delivery)


Sperm
Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months

RBRC06451, C57BL/6N-Dctn2<tm1b(EUCOMM)Hmgu>/E10

RBRC No. RBRC06451
Type Targeted MutationCartagena
Species Mus musculus
Strain name C57BL/6N-Dctn2<tm1b(EUCOMM)Hmgu>/E10
Former Common name No Data
H-2 Haplotype No Data
ES cell line JM8A3.N1 [C57BL/6N-A]
Background strain C57BL/6NTac
Appearance
1 Appearance No Data
Genotype No Data
Strain description No Data
Health Report No Data
Gene Details
Promoter No Data
1 Symbol Dctn2
Symbol name dynactin 2
Chromosome 10
Common name No Data
Symbol description No Data
References No Data

Research applications No Data
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The RECIPIENT should acknowledge the EUCOMM, RIKEN BRC and the International Mouse Phenotyping Consortium as the original creator of the targeted mouse ES cells and the provider of the knockout mice, respectively.
Additional information
1 No Data
Depositor RIKEN, BioResource Center
Strain Status /
Availability
(Expected delivery)


Sperm
Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months