RBRC02273, CB.Cg-Emx1<tm1Sia>/SiaRbrc

RBRC No. RBRC02273
Type Targeted MutationCartagena
Species Mus musculus
Strain name CB.Cg-Emx1<tm1Sia>/SiaRbrc
Former Common name Emx1(-) (Acc. No. CDB0021K)
H-2 Haplotype No Data
ES cell line TT2 [(C57BL/6NCrlj x CBA/JNCrlj)F1]
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain description No Data
Health Report No Data
Gene Details
Promoter No Data
1 Symbol neo
Symbol name neomycin resistance gene (E. coli)
Chromosome 6
Common name neo; neomycin;
Symbol description No Data
2 Symbol Emx1
Symbol name empty spiracles homolog 1 (Dorosophila)
Chromosome 6
Common name No Data
Symbol description No Data
References

Research applications Developmental Biology Research
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
(1) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the Accession No. CDB0021K and the BIOLOGICAL RESOURCE is requested (http://www.cdb.riken.jp/arg/mutant%20mice%20list.html). (2) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the literature designed by the DEPOSITOR is requested, Development 124, 101-111 (1997). (3) Please inform the DEVELOPER (mutant@cdb.riken.jp) about the paper when published.
Additional information
1 No Data
Depositor RIKEN, CDB (RIKEN Center for Developmental Biology) RIKEN, CDB
Strain Status /
Availability
(Expected delivery)


Preparing for distribution
Preparing for distribution
(Please note that it may take more than 6 months to make arrangements to distribute.)

Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

RBRC02596, Ripply2(lacZ) (Acc. No. CDB0455K)

RBRC No. RBRC02596
Type Targeted MutationCartagena
Species Mus musculus
Strain name Ripply2(lacZ) (Acc. No. CDB0455K)
Former Common name No Data
H-2 Haplotype No Data
ES cell line TT2 [(C57BL/6NCrlj x CBA/JNCrlj)F1]
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain description No Data
Health Report No Data
Gene Details
Promoter No Data
1 Symbol Ripply2
Symbol name ripply2 homolog (zebrafish)
Chromosome 9
Common name C030002E08Rik, LOC382089
Symbol description No Data
2 Symbol neo
Symbol name neomycin resistance gene (E. coli)
Chromosome 9
Common name neo; neomycin;
Symbol description No Data
3 Symbol lacZ
Symbol name beta-galactosidase (E. coli)
Chromosome 9
Common name No Data
Symbol description E. coli beta galactosidase
References FEBS Lett. 2007 May 21;.

Ripply2 is essential for precise somite formation during mouse early development.
Research applications Developmental Biology Research
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
(1) The RECIPIENT shall obtain a prior agreement from Dr. Makoto ASASHIMA (asashi@bio.c.u-tokyo.ac.jp) to transfer the BIOLOGICAL RESOURCE. (2) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the Accession No. CDB0455K and the BIOLOGICAL RESOURCE is requested. (3) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the literature designed by the DEPOSITOR is requested, FEBS Lett. 2007 Jul 12; 581 (14): 2691-6. (4) Please inform the DEPOSITOR (mutant@cdb.riken.jp) about the paper when published.
Additional information
1 No Data
Depositor RIKEN, CDB (RIKEN Center for Developmental Biology) RIKEN, CDB
Strain Status /
Availability
(Expected delivery)


Preparing for distribution
Preparing for distribution
(Please note that it may take more than 6 months to make arrangements to distribute.)

Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

RBRC03510, B6.Cg-Tg(Fabp4-Foxo1*d256)/Rbrc

RBRC No. RBRC03510
Type TransgeneCartagena
Species Mus musculus
Strain name B6.Cg-Tg(Fabp4-Foxo1*d256)/Rbrc
Former Common name FoxO1(aP2-FLAG-Δ256 ) (Acc.No. CDB0450T)
H-2 Haplotype No Data
ES cell line TT2 [(C57BL/6NCrlj x CBA/JNCrlj)F1]
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain description No Data
Health Report No Data
Gene Details
Promoter No Data
1 Symbol No Data
Symbol name No Data
Chromosome No Data
Common name No Data
Symbol description No Data
References Diabetes. 2008 Mar;57(3):563-76. Epub 2007 Dec 27.

Forkhead transcription factor FoxO1 in adipose tissue regulates energy storage and expenditure.
Research applications No Data
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
(1) The RECIPIENT shall obtain a prior agreement from Dr. Masato Kasuga (kasuga@ri.imcj.go.jp) to transfer the BIOLOGICAL RESOURCE. (2) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the Accession No. (CDB0450T) (http:www.cdb.riken.jp/arg/mutant%20mice%20list.html) and the BIOLOGICAL RESOURCE is requested. (3) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the literature designed by the DEPOSITOR is requested. (Diabetes. 2008 57(3):563-76.) (4) Please inform the DEPOSITOR (mutant@cdb.riken.jp) about the paper when published.
Additional information
1 No Data
Depositor RIKEN, CDB (RIKEN Center for Developmental Biology) RIKEN, CDB
Strain Status /
Availability
(Expected delivery)


Preparing for distribution
Preparing for distribution
(Please note that it may take more than 6 months to make arrangements to distribute.)

Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

RBRC04400, aquaporin 4 (GFP)-4 (Acc.No. CDB0758K-1)

RBRC No. RBRC04400
Type Targeted MutationCartagena
Species Mus musculus
Strain name aquaporin 4 (GFP)-4 (Acc.No. CDB0758K-1)
Former Common name No Data
H-2 Haplotype No Data
ES cell line TT2 [(C57BL/6NCrlj x CBA/JNCrlj)F1]
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain development Masato Yasui, School of Medicine, Keio University/Johns Hopkins University and Laboratory for Animal Resources and Genetic Engineering, RIKEN Center for Developmental Biology.
Strain description aquaporin 4 gene GFP knock-in mice. EGFP-Pgk-neo type (#5 ES clone derived)(B6 mixed: RBRC04397, BALB/c background: RBRC04399), delta Pgk-neo type (#5 ES clone derived)(B6 background: RBRC04364, BALB/c mixed: RBRC04400), delta EGFP-Pgk-neo type (#5 ES clone derived)(B6 mixed: RBRC04401, BALB/c mixed: RBRC04402), EGFP-Pgk-neo type (#50 ES clone derived)(B6 mixed: RBRC04398), delta Pgk-neo type (#50 ES clone derived)(B6 mixed: RBRC04403).
Colony maintenance Homozygote x Homozygote [or Crossing to BALB/cAJcl]
Health Report No Data
Gene Details
Promoter No Data
1 Symbol No Data
Symbol name No Data
Chromosome No Data
Common name No Data
Symbol description No Data
References

Research applications Cre/loxP system,
FLP/frt system,
Fluorescent Proteins/lacZ System
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
(1) The RECIPIENT shall obtain a prior agreement from Dr. Masato Yasui (myasui@a3.keio.jp) to transfer the BIOLOGICAL RESOURCE. (2) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the Accession No. (CDB0758K-1) (http:www.cdb.riken.jp/arg/mutant%20mice%20list.html) and the BIOLOGICAL RESOURCE is requested. (3) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the literature designed by the DEPOSITOR is requested. (未発表) (4) Please inform the DEPOSITOR (mutant@cdb.riken.jp) about the paper when published.
Additional information
1 GFP Transfer License (Japanese / English)
Please fill in the Schedule A, and submit two signed copies to us together with two signed copies of RIKEN BRC’s MTA. Please also read Schedule B.
2 Genotyping protocol <PCR>
Depositor RIKEN, CDB (RIKEN Center for Developmental Biology) RIKEN, CDB
Strain Status /
Availability
(Expected delivery)


Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

Sperm
Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months

RBRC05275, Vlk (Acc. No. CDB0434K)

RBRC No. RBRC05275
Type Targeted MutationCartagena
Species Mus musculus
Strain name Vlk (Acc. No. CDB0434K)
Former Common name No Data
H-2 Haplotype No Data
ES cell line TT2 [(C57BL/6NCrlj x CBA/JNCrlj)F1]
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain development Developed by Shin-Ichi Nishikawa, RIKEN Center for Developmental Biology.
Strain description Pkdcc, protein kinase domain containing, cytoplasmic knockout mice (24247-venus-LNL). Homozygous mice die soon after birth due to respiratory failure.
Colony maintenance Heterozygote x Wild-type [C57BL/6N]
Health Report
Gene Details
Promoter No Data
1 Symbol Pkdcc
Symbol name protein kinase domain containing, cytoplasmic;
Chromosome 17
Common name No Data
Symbol description No Data
2 Symbol Venus
Symbol name Green Fluorescent Protein, F46L (Jellyfish)
Chromosome 17
Common name No Data
Symbol description No Data
3 Symbol loxP
Symbol name phage P1 loxP
Chromosome 17
Common name No Data
Symbol description No Data
References

Research applications Cre/loxP system,
Developmental Biology Research,
Fluorescent Proteins/lacZ System
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
(1) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the Acc.No. CDB0434K and Web. Site (http://www.cdb.riken.jp/arg/mutant%20mice%20list.html) is requested. (2) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the literature designed by the DEPOSITOR is requested. (Development. 2009 136(12):2069-79.) (4) Please inform the DEPOSITOR (mutant@cdb.riken.jp) about the paper when published.
Additional information
1 No Data
2 Genotyping protocol <PCR>
Depositor RIKEN, CDB (RIKEN Center for Developmental Biology) RIKEN, CDB
Strain Status /
Availability
(Expected delivery)


Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

Sperm
Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months

RBRC05385, Dppa3-MER-Cre-MER-PEST (Acc. No. CDB0475T)

RBRC No. RBRC05385
Type TransgeneCartagena
Species Mus musculus
Strain name Dppa3-MER-Cre-MER-PEST (Acc. No. CDB0475T)
Former Common name No Data
H-2 Haplotype No Data
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain development Developed by Takayuki Hirota and Mitinori Saitou, Graduate School of Medicine, Kyoto University in 2011. Transgene was injected into the pronuclei of B6D2F2 fertilized eggs. The mice were crossed to C57BL/6.
Strain description This transgenic mouse expresses MER-Cre-MER-PEST protein under the control of the regulatory elements of the Dppa3. This strain enables 4-Hydroxytamoxifen-dependent Cre recombination in preimplantation embryos, primordial germ cells, and oocytes.
Colony maintenance Carrier x Nocarrier [C57BL/6N]
Health Report
Gene Details
Promoter No Data
1 Symbol No Data
Symbol name SV40 polyA
Chromosome UN
Common name No Data
Symbol description No Data
2 Symbol FLAG
Symbol name FLAG tag (synthetic)
Chromosome UN
Common name No Data
Symbol description No Data
3 Symbol Odc1
Symbol name mouse ornithine decarboxylase (PEST sequence) cDNA
Chromosome UN
Common name No Data
Symbol description No Data
4 Symbol cre
Symbol name Phage P1 Cre recombinase
Chromosome UN
Common name No Data
Symbol description No Data
5 Symbol hyg
Symbol name hygromycin phasphotransferase (E. coli)
Chromosome UN
Common name No Data
Symbol description No Data
6 Symbol neo
Symbol name neomycin resistance gene (E. coli)
Chromosome UN
Common name No Data
Symbol description No Data
References

Research applications Cre/loxP system
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
(1) The RECIPIENT shall obtain a prior agreement from the DEVELOPER (Dr. Mitinori Saitou, Kyoto University, E-mail: saitou@anat2.med.kyoto-u.ac.jp) to transfer the BIOLOGICAL RESOURCE. (2) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the Acc.No. CDB0475T and Web. Site (http://www.cdb.riken.jp/arg/mutant%20mice%20list.html) is requested. (3) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the literature designed by the DEPOSITOR is requested. (Biol Reprod. 2011 85(2):367-77.) (4) Please inform the DEPOSITOR (mutant@cdb.riken.jp) about the paper when published.
Additional information
1 Mouse of the Month Aug 2013
2 Genotyping protocol <PCR>
Depositor RIKEN, CDB (RIKEN Center for Developmental Biology) RIKEN, CDB
Strain Status /
Availability
(Expected delivery)


Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

Sperm
Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months

RBRC09341, IL-33(Acc.No.CDB0631K)

RBRC No. RBRC09341
Type Targeted MutationCartagena
Species Mus musculus
Strain name IL-33(Acc.No.CDB0631K)
Former Common name No Data
H-2 Haplotype No Data
ES cell line TT2 [(C57BL/6NCrlj x CBA/JNCrlj)F1]
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain description No Data
Health Report No Data
Gene Details
Promoter No Data
1 Symbol GFP
Symbol name Green Fluorescent Protein (Jellyfish)
Chromosome 19
Common name No Data
Symbol description No Data
2 Symbol Il33
Symbol name interleukin 33
Chromosome 19
Common name No Data
Symbol description No Data
3 Symbol loxP
Symbol name phage P1 loxP
Chromosome 19
Common name No Data
Symbol description No Data
Promoter mouse phosphoglycerate kinase promoter (PGK promoter)
4 Symbol neo
Symbol name neomycin resistance gene (E. coli)
Chromosome 19
Common name No Data
Symbol description No Data
References No Data

Research applications Cre/loxP system,
Fluorescent Proteins/lacZ System
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
(1) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the Acc.No. CDB0631K and Web Site (www2.clst.riken.jp/arg/mutant%20mice%20list.html) is requested. (2) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the literature designed by the DEPOSITOR is requested (Proc Natl Acad Sci U S A. 2010 107(43):18581-6.). (3) Please inform the DEPOSITOR (mutant@cdb.riken.jp) about the paper when published.
Additional information
1 GFP Transfer License (Japanese / English)
Please fill in the Schedule A, and submit two signed copies to us together with two signed copies of RIKEN BRC’s MTA. Please also read Schedule B.
Depositor RIKEN, CDB (RIKEN Center for Developmental Biology) RIKEN, CDB
Strain Status /
Availability
(Expected delivery)


Preparing for distribution
Preparing for distribution
(Please note that it may take more than 6 months to make arrangements to distribute.)

Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

RBRC10157, Gomafu null Neo-(Acc.No.CDB1377K)

RBRC No. RBRC10157
Type Targeted MutationCartagena
Species Mus musculus
Strain name Gomafu null Neo-(Acc.No.CDB1377K)
Former Common name No Data
H-2 Haplotype No Data
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain description No Data
Health Report
Gene Details
Promoter No Data
1 Symbol Miat
Symbol name myocardial infarction associated transcript (non-protein coding)
Chromosome 5
Common name No Data
Symbol description No Data
2 Symbol loxP
Symbol name phage P1 loxP
Chromosome 5
Common name No Data
Symbol description No Data
References No Data

Research applications Cre/loxP system
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the following literature(s) designated by the DEPOSITOR is requested.
Sci. Rep., 6:27204 (2016).
(1) The RECIPIENT shall obtain a prior agreement from the DEVELOPER (Dr. Shinichi Nakagawa (nakagawas@pharm.hokudai.ac.jp)) to transfer the BIOLOGICAL RESOURCE. (2) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the Accession No. (CDB1377K) and Web Site (www2.clst.riken.jp/arg/mutant%20mice%20list.html) is requested. (3) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the literature designed by the DEPOSITOR is requested. (Sci. Rep., 6:27204 (2016).) (4) Please inform the DEPOSITOR (mutant@cdb.riken.jp) about the paper when published.
Additional information
1 No Data
2 Genotyping protocol <PCR>
Depositor RIKEN, CDB (RIKEN Center for Developmental Biology) RIKEN, CDB
Strain Status /
Availability
(Expected delivery)


Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

Sperm
Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months

Live
Live mouse :

RBRC02274, B6.Cg-Sapcd2<tm1Sia>/SiaRbrc

RBRC No. RBRC02274
Type Targeted MutationCartagena
Species Mus musculus
Strain name B6.Cg-Sapcd2<tm1Sia>/SiaRbrc
Former Common name ang(lacZ) (Acc. No. CDB0024K)
H-2 Haplotype No Data
ES cell line TT2 [(C57BL/6NCrlj x CBA/JNCrlj)F1]
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain description No Data
Health Report
Gene Details
Promoter No Data
1 Symbol Sapcd2
Symbol name suppressor APC domain containing 2
Chromosome 2
Common name 2010317E24Rik, 6030458L21Rik, ang
Symbol description No Data
2 Symbol neo
Symbol name neomycin resistance gene (E. coli)
Chromosome 2
Common name neo; neomycin;
Symbol description No Data
3 Symbol Frt
Symbol name yeast FRT (flippase recombination target) site
Chromosome 2
Common name No Data
Symbol description No Data
4 Symbol Frt
Symbol name yeast FRT (flippase recombination target) site
Chromosome 2
Common name No Data
Symbol description No Data
5 Symbol HBB2
Symbol name rabbit beta-globin poly A
Chromosome 2
Common name No Data
Symbol description No Data
6 Symbol lacZ
Symbol name beta-galactosidase (E. coli)
Chromosome 2
Common name No Data
Symbol description E. coli beta galactosidase
7 Symbol loxP
Symbol name phage P1 loxP
Chromosome 2
Common name No Data
Symbol description No Data
8 Symbol loxP
Symbol name phage P1 loxP
Chromosome 2
Common name No Data
Symbol description No Data
References Gene Expr Patterns. 2004 Dec;5(2):171-8.

ang is a novel gene expressed in early neuroectoderm, but its null mutant exhibits no obvious phenotype.
Research applications Cre/loxP system,
Developmental Biology Research,
FLP/frt system,
Fluorescent Proteins/lacZ System
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
(1) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the Accession No. CDB0024K and the BIOLOGICAL RESOURCE is requested (http://www.cdb.riken.jp/arg/mutant%20mice%20list.html). (2) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the literature designed by the DEPOSITOR is requested, Gene Expression Patterns 5, 171-178 (2004). (3) In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested, “We acknowledge Dr. AIZAWA and Laboratory for animal Resources and Genetic Engineering in CDB for providing us the ang mutant mice(Acc. No. CDB0024K).” (4) Please inform the DEVELOPER (mutant@cdb.riken.jp) about the paper when published.
Additional information
1 No Data
2 Genotyping protocol <PCR>
Depositor RIKEN, CDB (RIKEN Center for Developmental Biology) RIKEN, CDB
Strain Status /
Availability
(Expected delivery)


Sperm
Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months

RBRC02597, Hes7-Cre (Acc. No. CDB0551T)

RBRC No. RBRC02597
Type TransgeneCartagena
Species Mus musculus
Strain name Hes7-Cre (Acc. No. CDB0551T)
Former Common name No Data
H-2 Haplotype No Data
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain description No Data
Health Report
Gene Details
Promoter Hes7 promoter
1 Symbol cre
Symbol name Phage P1 Cre recombinase
Chromosome UN
Common name No Data
Symbol description No Data
References Dev Cell. 2007 Aug;13(2):298-304.

The initiation and propagation of Hes7 oscillation are cooperatively regulated by Fgf and notch signaling in the somite segmentation clock.
Research applications Cre/loxP system,
Developmental Biology Research
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
(1) The RECIPIENT shall obtain a prior agreement from Dr. Ryoichiro KAGEYAMA (rkageyam@virus.kyoto-u.ac.jp) to transfer the BIOLOGICAL RESOURCE. (2) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the Accession No. CDB0551T and the BIOLOGICAL RESOURCE is requested. (3) In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, a citation of the literature designed by the DEPOSITOR is requested, Dev Cell. 2007 Aug; 13 (2): 298-304. (4) Please inform the DEPOSITOR (mutant@cdb.riken.jp) about the paper when published.
Additional information
1 No Data
2 Genotyping protocol <PCR>
Depositor RIKEN, CDB (RIKEN Center for Developmental Biology) RIKEN, CDB
Strain Status /
Availability
(Expected delivery)


Sperm
Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months