RBRC00224, SL/Ni

RBRC No. RBRC00224
Type Inbred wks
Species Mus musculus
Strain name SL/Ni
Former Common name No Data
H-2 Haplotype q
Background strain SL/NiStm
Appearance
1 Appearance albino
Genotype No Data
Strain development This strain originated from outbred Swiss mice, and the four substrains of SL family had been established at Kyushyu University. SL/Kh and SL/Ni strains were deposited by Dr. Hayase Shisa, Saitama Cancer Center Institute.
Pregnant females were transferred to RIKEN Tsukuba Institute, their babies were cleaned up by Caesarean section, and introduced into the SPF facility.
Strain description This strain has been established in Japan. Outbred Swiss mouse origin. High incidence of lymphoma was found in SL/Am, and not in SL/Ni.
There are four substrains of SL family, DL/QDj, SL/Am, SL/Ni and SL/Kh. The SL/Ni and SL/Am strains are almost identical and share similar genetic background with the proto-SL strain.
Colony maintenance The mice are maintained by sister-brother mating. Females and males in the same litter are recommended to mate just after weaning. When females and males from the different litters are used, males of 8-12 weeks old and females of 4-8 weeks old breed well.
Health Report
Gene Details
Promoter No Data
1 Symbol No Data
Symbol name No Data
Chromosome No Data
Common name No Data
Symbol description No Data
References Cancer Res. 1994 Jan 15;54(2):399-402.
Cancer Res. 1994 Jan 15;54(2):403-7.
Cancer Res. 1996 Aug 15;56(16):3716-20.
Cancer Res. 1999 Jun 1;59(11):2593-5.
J Exp Med. 1994 Dec 1;180(6):2155-62.
J Natl Cancer Inst. 1987 Oct;79(4):781-7.
Lab Anim Sci. 1996 Aug;46(4):410-7.
Proc Natl Acad Sci U S A. 2002 Jun 11;99(12):8253-8. Epub 2002 Jun 4.

Abnormal bone marrow B-cell differentiation in pre-B lymphoma-prone SL/Kh mice.
Abnormal bone marrow B-cell differentiation in pre-B lymphoma-prone SL/Kh mice.
Abnormal bone marrow B-cell differentiation in pre-B lymphoma-prone SL/Kh mice.
Abnormal bone marrow B-cell differentiation in pre-B lymphoma-prone SL/Kh mice.
Abnormal bone marrow B-cell differentiation in pre-B lymphoma-prone SL/Kh mice.
Abnormal bone marrow B-cell differentiation in pre-B lymphoma-prone SL/Kh mice.
Abnormal bone marrow B-cell differentiation in pre-B lymphoma-prone SL/Kh mice.
Abnormal bone marrow B-cell differentiation in pre-B lymphoma-prone SL/Kh mice.
Research applications Cancer Research
Specific Term and Conditions No specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.)
Additional information
1 No Data
Depositor Shisa, Hayase (Saitama Cancer Center) Shisa, Hayase
Strain Status /
Availability
(Expected delivery)


Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

RBRC00692, BALB/cAcc/Stm-nu

RBRC No. RBRC00692
Type Spontaneous Mutation
Species Mus musculus
Strain name BALB/cAcc/Stm-nu
Former Common name No Data
H-2 Haplotype No Data
Background strain BALB/c
Appearance
1 Appearance albino
Genotype No Data
Strain description No Data
Health Report
BRC facility Health Report in the last year and a half

Examination Date Room Rack
Sep 9, 2019 2-検 G
Jul 8, 2019 2-検 G
May 7, 2019 2-検 G
Mar 11, 2019 2-検 G
Jan 15, 2019 2-検 G
Nov 12, 2018 2-検 G
Sep 10, 2018 2-検 G
Jul 9, 2018 2-検 G

Gene Details
Promoter No Data
1 Symbol Foxn1
Symbol name forkhead box N1
Chromosome 11
Common name D11Bhm185e, Hfh11, whn
Symbol description No Data
References No Data

Research applications No Data
Specific Term and Conditions No specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.)
Additional information
1 No Data
Depositor Shisa, Hayase (Saitama Cancer Center) Shisa, Hayase
Strain Status /
Availability
(Expected delivery)


Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

Sperm
Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months

Live
Live mouse :

RBRC00011, AKR/Ms-Rb(6.15)

RBRC No. RBRC00011
Type Chromosomal Aberration 24wks,♂
Species Mus musculus
Strain name AKR/Ms-Rb(6.15)
Former Common name No Data
H-2 Haplotype k
Donor strain AKR-Rb(6.15)1Ald
Background strain AKR/Ms
Appearance
1 Appearance albino
Genotype a/a B/B c/c
Strain development AKR-Rb(6.15)1Ald/StmBrc. This strain have a Robertsonian translocation involving Chr 6 and Chr 15, the 1st chromosome anomaly from Dr. Adler Leonard’s lab. This strain is useful as genetic research tools.
Strain description Chromosomal abbreviation originally arose in AKR/J at Dr. Adler Leonard’s lab in 1996. The AKR/Ms-Rb(6.15) strain was generated by backcrossed to AKR/Ms by Dr. Izumi Shisa at Saitama Cancer Institute.
Colony maintenance Sibling Mating (Homozygote x Homozygote)
Health Report
Gene Details
Promoter No Data
1 Symbol Rb(6.15)1Ald
Symbol name Robertsonian translocation, Chr 6 and 15
Chromosome 15
Common name Rb1Ald
Symbol description No Data
2 Symbol Rb(6.15)1Ald
Symbol name Robertsonian translocation, Chr 6 and 15
Chromosome 6
Common name Rb1Ald
Symbol description No Data
References Cancer Genet Cytogenet. 1983 Jun;9(2):151-66.

Trisomy of chromosome 6.15 is not necessary for proliferation of AKR(Rb6.15)1Ald lymphoma cells.
Research applications Cancer Research,
Genetics Research
Specific Term and Conditions No specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.)
Additional information
1 No Data
Depositor Shisa, Hayase (Saitama Cancer Center) Shisa, Hayase
Strain Status /
Availability
(Expected delivery)


Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

RBRC00693, AKR/J-nu str

RBRC No. RBRC00693
Type Spontaneous Mutation
Species Mus musculus
Strain name AKR/J-nustr
Former Common name No Data
H-2 Haplotype k
Background strain No Data
Appearance
1 Appearance albino
Genotype No Data
2 Appearance albino nude
Genotype nu
Strain description No Data
Health Report No Data
Gene Details
Promoter No Data
1 Symbol Foxn1
Symbol name forkhead box N1
Chromosome 11
Common name D11Bhm185e, Hfh11, whn
Symbol description No Data
References No Data

Research applications No Data
Specific Term and Conditions No specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.)
Additional information
1 No Data
Depositor Shisa, Hayase (Saitama Cancer Center) Shisa, Hayase
Strain Status /
Availability
(Expected delivery)


Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

RBRC00012, AKR/Ms-Rb(6.15)- Foxn1 nu

RBRC No. RBRC00012
Type Spontaneous Mutation Congenic 8wks,♂
Species Mus musculus
Strain name AKR/Ms-Rb(6.15)-Foxn1nu
Former Common name No Data
H-2 Haplotype No Data
Background strain AKR
Appearance
1 Appearance albino, hairless albino
Genotype nu/+, Rb
Strain description No Data
Health Report No Data
Gene Details
Promoter No Data
1 Symbol Foxn1
Symbol name forkhead box N1
Chromosome 11
Common name D11Bhm185e, Hfh11, whn
Symbol description No Data
2 Symbol Rb(6.15)1Ald
Symbol name Robertsonian translocation, Chr 6 and 15
Chromosome 15
Common name Rb1Ald
Symbol description No Data
3 Symbol Rb(6.15)1Ald
Symbol name Robertsonian translocation, Chr 6 and 15
Chromosome 6
Common name Rb1Ald
Symbol description No Data
References Cancer Genet Cytogenet. 1983 Jun;9(2):151-66.

Trisomy of chromosome 6.15 is not necessary for proliferation of AKR(Rb6.15)1Ald lymphoma cells.
Research applications Cancer Research
Specific Term and Conditions No specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.)
Additional information
1 No Data
Depositor Shisa, Hayase (Saitama Cancer Center) Shisa, Hayase
Strain Status /
Availability
(Expected delivery)


Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

RBRC00034, C57BL/10-mt<ddY>/StmRbrc

RBRC No. RBRC00034
Type Spontaneous Mutation
Species Mus musculus
Strain name C57BL/10-mt<ddY>/StmRbrc
Former Common name B10mtJ
H-2 Haplotype No Data
Background strain C57BL/10
Appearance
1 Appearance black
Genotype No Data
Strain description mitochondrial gene mutation
Health Report No Data
Gene Details
Promoter No Data
1 Symbol No Data
Symbol name No Data
Chromosome No Data
Common name No Data
Symbol description No Data
References No Data

Research applications No Data
Specific Term and Conditions No specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.)
Additional information
1 No Data
Depositor Shisa, Hayase (Saitama Cancer Center) Shisa, Hayase
Strain Status /
Availability
(Expected delivery)


Preparing for distribution
Preparing for distribution
(Please note that it may take more than 6 months to make arrangements to distribute.)

Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

RBRC00093, C3H-fBi

RBRC No. RBRC00093
Type Inbred
Species Mus musculus
Strain name C3H-fBi
Former Common name No Data
H-2 Haplotype k
Background strain C3H
Appearance
1 Appearance agouti, retinal degeneration
Genotype A/A Pde6brd1/Pde6brd1
Strain description No Data
Health Report No Data
Gene Details
Promoter No Data
1 Symbol Pde6b
Symbol name phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide
Chromosome 5
Common name nmf137, Pdeb, r, rd, rd10
Symbol description No Data
References No Data

Research applications Sensorineural Research
Specific Term and Conditions No specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.)
Additional information
1 No Data
Depositor Shisa, Hayase (Saitama Cancer Center) Shisa, Hayase
Strain Status /
Availability
(Expected delivery)


Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

RBRC00094, C3H-fBi-Rb(6.15)

RBRC No. RBRC00094
Type Chromosomal Aberration 12wks,♂
Species Mus musculus
Strain name C3H-fBi-Rb(6.15)
Former Common name No Data
H-2 Haplotype No Data
Background strain C3H
Appearance
1 Appearance agouti
Genotype No Data
Strain description No Data
Health Report
Gene Details
Promoter No Data
1 Symbol Rb(6.15)1Ald
Symbol name Robertsonian translocation, Chr 6 and 15
Chromosome 15
Common name Rb1Ald
Symbol description No Data
2 Symbol Rb(6.15)1Ald
Symbol name Robertsonian translocation, Chr 6 and 15
Chromosome 6
Common name Rb1Ald
Symbol description No Data
References No Data

Research applications Genetics Research
Specific Term and Conditions No specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.)
Additional information
1 No Data
Depositor Shisa, Hayase (Saitama Cancer Center) Shisa, Hayase
Strain Status /
Availability
(Expected delivery)


Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

RBRC00134, C57BL/6-Lyst<bg-J>/StmRbrc

RBRC No. RBRC00134
Type Spontaneous Mutation Congenic wks
Species Mus musculus
Strain name C57BL/6-Lyst<bg-J>/StmRbrc
Former Common name C57BL/6-bg/bg
H-2 Haplotype b
Background strain C57BL/6J
Appearance
1 Appearance light black
Genotype aaBBCC;bgJ/bgJ
Strain development Jackson Laboratory – Aichi Cancer Center Research Institute (1973?) – Saitama Cancer Center (1977, F16).
Strain description Beige spontaneous mutant mice. Homozygous mutant mice snow a phenotype similar to human Chediak-Higashi syndrome.
Colony maintenance Homozygote x Homozygote
Health Report
Gene Details
Promoter No Data
1 Symbol Lyst
Symbol name lysosomal trafficking regulator
Chromosome 13
Common name beige, bg, D13Sfk13
Symbol description No Data
References Nature. 1996 Jul 18;382(6588):262-5.

Identification of the homologous beige and Chediak-Higashi syndrome genes.
Research applications Dermatology Research,
Hematological Research,
Immunology and Inflammation Research,
Internal/Organ Research,
Metabolism Research,
Mouse Models for Human Disease
Specific Term and Conditions No specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.)
Additional information
1 No Data
Depositor Shisa, Hayase (Saitama Cancer Center) Shisa, Hayase
Strain Status /
Availability
(Expected delivery)


Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

RBRC00135, C57BL/6J-bg/bg- Foxn1 nu

RBRC No. RBRC00135
Type Spontaneous Mutation Congenic
Species Mus musculus
Strain name C57BL/6J-bg/bg-Foxn1nu
Former Common name No Data
H-2 Haplotype No Data
Background strain C57BL/6J
Appearance
1 Appearance black
Genotype No Data
Strain description No Data
Health Report No Data
Gene Details
Promoter No Data
1 Symbol Foxn1
Symbol name forkhead box N1
Chromosome 11
Common name D11Bhm185e, Hfh11, whn
Symbol description No Data
2 Symbol Lyst
Symbol name lysosomal trafficking regulator
Chromosome 13
Common name beige, bg, D13Sfk13
Symbol description No Data
References No Data

Research applications No Data
Specific Term and Conditions No specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.)
Additional information
1 No Data
Depositor Shisa, Hayase (Saitama Cancer Center) Shisa, Hayase
Strain Status /
Availability
(Expected delivery)


Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months