RBRC00127, C57BL/6-Lyb-2.1

RBRC No. RBRC00127
Type Congenic wks
Species Mus musculus
Strain name C57BL/6-Lyb-2.1
Former Common name No Data
H-2 Haplotype No Data
Background strain No Data
Appearance
1 Appearance black
Genotype No Data
Strain description No Data
Health Report No Data
Gene Details
Promoter No Data
1 Symbol Cd72
Symbol name CD72 antigen
Chromosome 4
Common name Ly-19, Ly-32, Ly-m19, Lyb-2
Symbol description No Data
References No Data

Research applications No Data
Specific Term and Conditions No specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.)
Additional information
1 No Data
Depositor Takahashi, Toshitada (Aichi Cancer Center) Takahashi, Toshitada
Strain Status /
Availability
(Expected delivery)


Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

RBRC00309, 171

RBRC No. RBRC00309
Type TransgeneCartagena
Species Mus musculus
Strain name 171
Former Common name No Data
H-2 Haplotype No Data
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain description No Data
Health Report No Data
Gene Details
Promoter No Data
1 Symbol No Data
Symbol name No Data
Chromosome No Data
Common name No Data
Symbol description No Data
References Genetics in Wild Mice, 159-177 (1994).

Research applications No Data
Specific Term and Conditions No specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.)
Additional information
1 No Data
Depositor Takahashi, Toshitada (Aichi Cancer Center) Takahashi, Toshitada
Strain Status /
Availability
(Expected delivery)


Preparing for distribution
Preparing for distribution
(Please note that it may take more than 6 months to make arrangements to distribute.)

Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

RBRC00128, B6.C-Enpp1<a>/Rbrc

RBRC No. RBRC00128
Type Congenic
Species Mus musculus
Strain name B6.C-Enpp1<a>/Rbrc
Former Common name C57BL/6-PC(+), B6-PC<+>, C57BL/6-Enpp1
H-2 Haplotype No Data
Background strain No Data
Appearance
1 Appearance black
Genotype No Data
Strain development Developed by Toshitada Takahashi, Aichi Cancer Center Research Institute.
Strain description C-1 congenic strain. BALB/c background strain (RBRC00062) having negative typed plasma cell antigen (PC-1 negative, Enpp1<b>) from C57BL/6. C57BL/6 background strain (RBRC00128) having positive type plasma cell antigen (PC-1 positive, Enpp1<a>) from BALB/c.
Colony maintenance Homozygote x Homozygote
Health Report No Data
Gene Details
Promoter No Data
1 Symbol Enpp1
Symbol name ectonucleotide pyrophosphatase/phyosphodiesterase 1
Chromosome 10
Common name No Data
Symbol description No Data
References

Research applications No Data
Specific Term and Conditions No specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.)
Additional information
1 No Data
Depositor Takahashi, Toshitada (Aichi Cancer Center) Takahashi, Toshitada
Strain Status /
Availability
(Expected delivery)


Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

RBRC00310, 221

RBRC No. RBRC00310
Type TransgeneCartagena
Species Mus musculus
Strain name 221
Former Common name No Data
H-2 Haplotype No Data
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain description No Data
Health Report No Data
Gene Details
Promoter No Data
1 Symbol No Data
Symbol name No Data
Chromosome No Data
Common name No Data
Symbol description No Data
References Genetics in Wild Mice, 159-177 (1994).

Research applications No Data
Specific Term and Conditions No specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.)
Additional information
1 No Data
Depositor Takahashi, Toshitada (Aichi Cancer Center) Takahashi, Toshitada
Strain Status /
Availability
(Expected delivery)


Preparing for distribution
Preparing for distribution
(Please note that it may take more than 6 months to make arrangements to distribute.)

Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

RBRC00130, C57BL/6-Tla a

RBRC No. RBRC00130
Type Congenic wks
Species Mus musculus
Strain name C57BL/6-Tlaa
Former Common name No Data
H-2 Haplotype No Data
Background strain No Data
Appearance
1 Appearance black
Genotype No Data
Strain description No Data
Health Report No Data
Gene Details
Promoter No Data
1 Symbol H2-T18
Symbol name histocompatibility 2, T region locus 18
Chromosome 17
Common name H-2T18, Tla
Symbol description No Data
References No Data

Research applications No Data
Specific Term and Conditions No specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.)
Additional information
1 No Data
Depositor Takahashi, Toshitada (Aichi Cancer Center) Takahashi, Toshitada
Strain Status /
Availability
(Expected delivery)


Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

RBRC00311, HKB5

RBRC No. RBRC00311
Type TransgeneCartagena
Species Mus musculus
Strain name HKB5
Former Common name No Data
H-2 Haplotype No Data
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain description No Data
Health Report No Data
Gene Details
Promoter No Data
1 Symbol No Data
Symbol name No Data
Chromosome No Data
Common name No Data
Symbol description No Data
References Genetics in Wild Mice, 159-177 (1994).

Research applications No Data
Specific Term and Conditions No specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.)
Additional information
1 No Data
Depositor Takahashi, Toshitada (Aichi Cancer Center) Takahashi, Toshitada
Strain Status /
Availability
(Expected delivery)


Preparing for distribution
Preparing for distribution
(Please note that it may take more than 6 months to make arrangements to distribute.)

Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

RBRC00144, C57BL/6-Ly5.1

RBRC No. RBRC00144
Type Congenic
Species Mus musculus
Strain name C57BL/6-Ly5.1
Former Common name C57BL/6-Ly-5.1
H-2 Haplotype No Data
Background strain C57BL/6
Appearance
1 Appearance black
Genotype a/a B/B C/C
Strain development Deposited by Toshitada Takahashi, Aichi Cancer Center.
Strain description This is a B6 background congenic strain that having differential B cell antigen designated as Ly5.1. This strain is useful as tissue/cell and B cell markers in transplantation studies.
Colony maintenance Homozygote x Homozygote
Health Report
Gene Details
Promoter No Data
1 Symbol Ptprc
Symbol name protein tyrosine phosphatase
Chromosome 1
Common name B220, CD45, Cd45, CD45R, Ly-5, LY-5, Lyt-4, T200, CD45.1
Symbol description No Data
References No Data

Research applications Immunology and Inflammation Research
Specific Term and Conditions No specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.)
Additional information
1 Mouse of the Month Jun 2009
Genetic Background
2 Genotyping protocol <PCR>
Depositor Takahashi, Toshitada (Aichi Cancer Center) Takahashi, Toshitada
Strain Status /
Availability
(Expected delivery)


Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

Sperm
Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months

Live
Live mouse :
BRC mice in Publications
Title Journal
(PMID)
Author
Repopulating activity of ex vivo-expanded murine hematopoietic stem cells resides in the CD48-c-Kit+Sca-1+lineage marker- cell population. Stem Cells.26(3): 646-55 (2008).(18079432)
Noda S, Horiguchi K, Ichikawa H, Miyoshi H.
Identification of genes potentially involved in supporting hematopoietic stem cell activity of stromal cell line MC3T3-G2/PA6. Int J Hematol.87(3): 239-45 (2008).(18317883)
Shimizu N, Noda S, Katayama K, Ichikawa H, Kodama H, Miyoshi H.
The NF-kappaB RelA subunit confers resistance to Leishmania major by inducing nitric oxide synthase 2 and Fas expression but not Th1 differentiation. J Immunol.182(8): 1098071 (2009).(19342670)
Mise-Omata S, Kuroda E, Sugiura T, Yamashita U, Obata Y, Doi TS.
Mitochondrial respiration defects modulate differentiation but not proliferation of hematopoietic stem and progenitor cells. FEBS Lett.584(15): 547377 (2010).(20600007)
Inoue S, Noda S, Kashima K, Nakada K, Hayashi J, Miyoshi H.
Successful differentiation to T cells, but unsuccessful B-cell generation, from B-cell-derived induced pluripotent stem cells. Int Immunol.23(1): 65-74 (2011).(21135032)
Wada H, Kojo S, Kusama C, Okamoto N, Sato Y, Ishizuka B, Seino K.
IL-17/IFN-gamma double producing CD8+ T (Tc17/IFN-gamma) cells: A novel cytotoxic T-cell subset converted from Tc17 cells by IL-12. Int Immunol. (2011).(22039016)
Tajima M, Wakita D, Satoh T, Kitamura H, Nishimura T.
The development of IL-17/IFN-gamma-double producing CTLs from Tc17 cells is driven by epigenetic suppression of Socs3 gene promoter. Eur J Immunol. (2012).(22674086)
Satoh T, Tajima M, Wakita D, Kitamura H, Nishimura T.
PAD4 regulates proliferation of multipotent haematopoietic cells by controlling c-myc expression. Nat Commun.4: 1836 (2013).(23673621)
Nakashima K, Arai S, Suzuki A, Nariai Y, Urano T, Nakayama M, Ohara O, Yamamura K, Yamamoto K, Miyazaki T.
Th2-type inflammation instructs inflammatory dendritic cells to induce airway hyperreactivity. Int Immunol. (2013).(24150243)
Iwata A, Kawashima S, Kobayashi M, Okubo A, Kawashima H, Suto A, Hirose K, Nakayama T, Nakajima H.
NF-kappaB RELA-deficient bone marrow macrophages fail to support bone formation and to maintain hematopoietic niche after lethal irradiation and stem cell transplantation. Int Immunol. (2014).(24908679)
Mise-Omata S, Alles N, Fukazawa T, Aoki K, Ohya K, Jimi E, Obata Y, Doi T.
Mature resting Ly6Chigh natural killer cells can be reactivated by IL 15. Eur. J. Immunol.44(9): 2638-47. (2014).(24995967)
Omi A, Enomoto Y, Kiniwa T, Miyata N, Miyajima A.
Artificially synthesized helper/killer-hybrid epitope long peptide (H/K-HELP): Preparation and immunological analysis of vaccine efficacy. Immunol Lett. (2014).(25479286)
Masuko K, Wakita D, Togashi Y, Kita T, Kitamura H, Nishimura T.
Fucci-guided purification of hematopoietic stem cells with high repopulating activity. Biochem Biophys Res Commun. (2014).(25534850)
Yo M, Sakaue-Sawano A, Noda S, Miyawaki A, Miyoshi H.
Overexpression of Cytotoxic T-Lymphocyte-Associated Antigen-4 Prevents Atherosclerosis in Mice Arterioscler Thromb Vasc Biol.36: 1141 (2016).(27055906)
Matsumoto T, Sasaki N, Yamashita T, Emoto T, Kasahara K, Mizoguchi T, Hayashi T, Yodoi K, Kitano N, Saito T, Yamaguchi T, Hirata K.
Oral CD103-CD11b+ classical dendritic cells present sublingual antigen and induce Foxp3+ regulatory T cells in draining lymph nodes. Mucosal Immunol. (2016).(27166558)
Tanaka Y, Nagashima H, Bando K, Lu L, Ozaki A, Morita Y, Fukumoto S, Ishii N, Sugawara S.
Inflammasome and Fas-Mediated IL-1beta Contributes to Th17/Th1 Cell Induction in Pathogenic Bacterial Infection In Vivo. J. Immunol.199(3): 1122-1130 (2017).(28674179)
Uchiyama R, Yonehara S, Taniguchi S, Ishido S, Ishii KJ, Tsutsui H.
Neutrophils alleviate fibrosis in the CCl4-induced mouse chronic liver injury model. Hepatol. Commun. (2018).(29881822)
Eiko Saijou Yutaka Enomoto Michitaka Matsuda Cindy Yuet-Yin Kok Shizuo Akira Minoru Tanaka Atsushi Miyajima.

RBRC00312, K4

RBRC No. RBRC00312
Type TransgeneCartagena
Species Mus musculus
Strain name K4
Former Common name Tg.Tlaa-3-1
H-2 Haplotype No Data
Background strain C3H/HeNCrlCrlj
Appearance
1 Appearance No Data
Genotype No Data
Strain description No Data
Health Report No Data
Gene Details
Promoter No Data
1 Symbol Tlaa-3
Symbol name TL antigen a-3
Chromosome UN
Common name No Data
Symbol description No Data
References Genetics in Wild Mice, 159-177 (1994).
J Exp Med. 1991 Aug 1;174(2):351-62.
Proc Natl Acad Sci U S A. 1989 Oct;86(20):7995-9.

Research applications No Data
Specific Term and Conditions No specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.)
Additional information
1 No Data
Depositor Takahashi, Toshitada (Aichi Cancer Center) Takahashi, Toshitada
Strain Status /
Availability
(Expected delivery)


Sperm
Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months

RBRC00191, GRS/A

RBRC No. RBRC00191
Type Inbred 12wks,♂
Species Mus musculus
Strain name GRS/A
Former Common name grs;
H-2 Haplotype ?
Background strain GRS/A
Appearance
1 Appearance albino
Genotype a/a Tyrc/Tyrc
Strain development Formerly called GR/A. Muhlbock 1965 from outbred mice obtained from
Grumbach in Zurich. Imported from Amsterdam, Netherland to Dr. Sakakura T, Aichi Cancer Cetnter Research Institute.
Strain description Breeding females have a high incidence of mammary tumours which are highly hormone-responsive.
Health Report
Gene Details
Promoter No Data
1 Symbol Mtv2
Symbol name mammary tumor virus locus 2
Chromosome 18
Common name No Data
Symbol description No Data
References Mammary tumors in the mouse. (1981).
Immunogenetics. 1992;36(3):189-94.
Int J Cancer. 1977 Mar 15;19(3):383-90.
J Natl Cancer Inst. 1976 Jan;56(1):27-32.
Virology. 1985 Apr 30;142(2):278-90.

Research applications Cancer Research,
Immunology and Inflammation Research,
Virology Research
Specific Term and Conditions No specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.)
Additional information
1 No Data
Depositor Takahashi, Toshitada (Aichi Cancer Center) Takahashi, Toshitada
Strain Status /
Availability
(Expected delivery)


Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

RBRC00313, DCR1

RBRC No. RBRC00313
Type TransgeneCartagena
Species Mus musculus
Strain name DCR1
Former Common name No Data
H-2 Haplotype No Data
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain description No Data
Health Report No Data
Gene Details
Promoter No Data
1 Symbol No Data
Symbol name No Data
Chromosome No Data
Common name No Data
Symbol description No Data
References No Data

Research applications No Data
Specific Term and Conditions No specific terms and conditions. (The DEPOSITOR waives its own rights under any patents, intellectual property, or other proprietary rights with respect to the results to be obtained by use of the BIOLOGICAL RESOURCE.)
Additional information
1 No Data
Depositor Takahashi, Toshitada (Aichi Cancer Center) Takahashi, Toshitada
Strain Status /
Availability
(Expected delivery)


Preparing for distribution
Preparing for distribution
(Please note that it may take more than 6 months to make arrangements to distribute.)

Sperm
Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months