RBRC01024, RIS:DBA/2 and BALB/c (CXD2-E)

RBRC No. RBRC01024
Type Recombinant Inbred
Species Mus musculus
Strain name RIS:DBA/2 and BALB/c (CXD2-E)
Former Common name No Data
H-2 Haplotype No Data
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain description No Data
Health Report
Gene Details
Promoter No Data
1 Symbol No Data
Symbol name No Data
Chromosome No Data
Common name No Data
Symbol description No Data
References No Data

Research applications No Data
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
Additional information
1 No Data
Depositor Guenet, Jean-Louis (Institut Pasteur) Guenet, Jean-Louis
Strain Status /
Availability
(Expected delivery)


Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

RBRC01025, RIS:DBA/2 and BALB/c (CXD2-D)

RBRC No. RBRC01025
Type Recombinant Inbred
Species Mus musculus
Strain name RIS:DBA/2 and BALB/c (CXD2-D)
Former Common name No Data
H-2 Haplotype No Data
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain description No Data
Health Report
Gene Details
Promoter No Data
1 Symbol No Data
Symbol name No Data
Chromosome No Data
Common name No Data
Symbol description No Data
References No Data

Research applications No Data
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
Additional information
1 No Data
Depositor Guenet, Jean-Louis (Institut Pasteur) Guenet, Jean-Louis
Strain Status /
Availability
(Expected delivery)


Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

RBRC00063, BALB/c-Reln rl-Orl /+

RBRC No. RBRC00063
Type Spontaneous Mutation 10wks,♀
Species Mus musculus
Strain name BALB/c-Relnrl-Orl/+
Former Common name BALB/c/Pas-Relnrl/+
H-2 Haplotype No Data
Background strain BALB/cA
Appearance
1 Appearance No Data
Genotype No Data
Strain description No Data
Health Report No Data
Gene Details
Promoter No Data
1 Symbol Reln
Symbol name reelin
Chromosome 5
Common name No Data
Symbol description No Data
References No Data

Research applications No Data
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR.
* The RIKEN BRC shall maintain, store, multiply and distribute the BIOLOGICAL RESOURCE in Japan only.
* Before any access to the biological resource, the Recipient will sign (as well as his/her administrative authority) the enclosed form to be sent to the Depositor (Institute Pasteur).
* Prior to applications for a patent, or intellectual property or other rights based on the results of research using the BIOLOGICAL RESOURCE, the recipient shall discuss such applications with the DEPOSITOR. Use of the BIOLOGICAL RESOURCE shall be a collaborative research with the DEPOSITOR. The DEPOSITOR requires to be co-owner for the inventions or other intellectual property generated by using the BIOLOGICAL RESOURCE.
Additional information
1 No Data
2 Genotyping protocol <PCR>
Depositor Guenet, Jean-Louis (Institut Pasteur) Guenet, Jean-Louis
Strain Status /
Availability
(Expected delivery)


Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months
BRC mice in Publications
Title Journal
(PMID)
Author
Genetic and animal model analyses reveal the pathogenic role of a novel deletion of RELN in schizophrenia. Sci. Rep.13046 (2018).(30158644)
Akira Sobue, Itaru Kushima, Taku Nagai, Wei Shan, Takao Kohno, Branko Aleksic, Yuki Aoyama, Daisuke Mori, Yuko Arioka, Naoko Kawano, Maeri Yamamoto, Mitsuharu Hattori, Toshitaka Nabeshima, Kiyofumi Yamada & Norio Ozaki.

RBRC01026, RIS:DBA/2 and BALB/c (CXD2-J)

RBRC No. RBRC01026
Type Recombinant Inbred
Species Mus musculus
Strain name RIS:DBA/2 and BALB/c (CXD2-J)
Former Common name No Data
H-2 Haplotype No Data
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain description No Data
Health Report
Gene Details
Promoter No Data
1 Symbol No Data
Symbol name No Data
Chromosome No Data
Common name No Data
Symbol description No Data
References No Data

Research applications No Data
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
Additional information
1 No Data
Depositor Guenet, Jean-Louis (Institut Pasteur) Guenet, Jean-Louis
Strain Status /
Availability
(Expected delivery)


Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

RBRC00071, BALB/c-crv4

RBRC No. RBRC00071
Type Spontaneous Mutation wks
Species Mus musculus
Strain name BALB/c-crv4
Former Common name No Data
H-2 Haplotype No Data
Background strain BALB/cPas
Appearance
1 Appearance No Data
Genotype No Data
Strain description No Data
Health Report
Gene Details
Promoter No Data
1 Symbol Grm1
Symbol name glutamate receptor, metabotropic 1
Chromosome 10
Common name crv4
Symbol description No Data
References No Data

Research applications No Data
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR.
* The RIKEN BRC shall maintain, store, multiply and distribute the BIOLOGICAL RESOURCE in Japan only.
* Before any access to the biological resource, the Recipient will sign (as well as his/her administrative authority) the enclosed form to be sent to the Depositor (Institute Pasteur).
* Prior to applications for a patent, or intellectual property or other rights based on the results of research using the BIOLOGICAL RESOURCE, the recipient shall discuss such applications with the DEPOSITOR. Use of the BIOLOGICAL RESOURCE shall be a collaborative research with the DEPOSITOR. The DEPOSITOR requires to be co-owner for the inventions or other intellectual property generated by using the BIOLOGICAL RESOURCE.
Additional information
1 No Data
2 Genotyping protocol <PCR>
Depositor Guenet, Jean-Louis (Institut Pasteur) Guenet, Jean-Louis
Strain Status /
Availability
(Expected delivery)


Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

RBRC01027, RIS:DBA/2 and BALB/c (CXD2-F)

RBRC No. RBRC01027
Type Recombinant Inbred wks
Species Mus musculus
Strain name RIS:DBA/2 and BALB/c (CXD2-F)
Former Common name No Data
H-2 Haplotype No Data
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain description No Data
Health Report
Gene Details
Promoter No Data
1 Symbol No Data
Symbol name No Data
Chromosome No Data
Common name No Data
Symbol description No Data
References No Data

Research applications No Data
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
Additional information
1 No Data
Depositor Guenet, Jean-Louis (Institut Pasteur) Guenet, Jean-Louis
Strain Status /
Availability
(Expected delivery)


Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

RBRC00121, C57BL/6-Krt2 SEG

RBRC No. RBRC00121
Type Spontaneous Mutation 18wks,♂
Species Mus musculus
Strain name C57BL/6-Krt2SEG
Former Common name No Data
H-2 Haplotype No Data
Background strain No Data
Appearance
1 Appearance black
Genotype No Data
Strain description No Data
Health Report No Data
Gene Details
Promoter No Data
1 Symbol Krt2
Symbol name keratin gene complex 2, basic
Chromosome 15
Common name Krt-2
Symbol description No Data
References No Data

Research applications No Data
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR.
In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
* The RIKEN BRC shall maintain, store, multiply and distribute the BIOLOGICAL RESOURCE in Japan only.
* Before any access to the biological resource, the Recipient will sign (as well as his/her administrative authority) the enclosed form to be sent to the Depositor (Institute Pasteur).
* Prior to applications for a patent, or intellectual property or other rights based on the results of research using the BIOLOGICAL RESOURCE, the recipient shall discuss such applications with the DEPOSITOR. Use of the BIOLOGICAL RESOURCE shall be a collaborative research with the DEPOSITOR. The DEPOSITOR requires to be co-owner for the inventions or other intellectual property generated by using the BIOLOGICAL RESOURCE.
Additional information
1 No Data
Depositor Guenet, Jean-Louis (Institut Pasteur) Guenet, Jean-Louis
Strain Status /
Availability
(Expected delivery)


Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

RBRC01028, RIS:DBA/2 and BALB/c (CXD2-L)

RBRC No. RBRC01028
Type Recombinant Inbred
Species Mus musculus
Strain name RIS:DBA/2 and BALB/c (CXD2-L)
Former Common name No Data
H-2 Haplotype No Data
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain description No Data
Health Report
Gene Details
Promoter No Data
1 Symbol No Data
Symbol name No Data
Chromosome No Data
Common name No Data
Symbol description No Data
References No Data

Research applications No Data
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
Additional information
1 No Data
Depositor Guenet, Jean-Louis (Institut Pasteur) Guenet, Jean-Louis
Strain Status /
Availability
(Expected delivery)


Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

RBRC00188, DW/Pas- tbl

RBRC No. RBRC00188
Type Spontaneous Mutation
Species Mus musculus
Strain name DW/Pas-tbl
Former Common name No Data
H-2 Haplotype No Data
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain description Tambaleante (tbl) mutant was occurred in the DW/J-Pas background, and foundin the CNRS breeding center of Orleans-La Source. This mutation isautosomal recessive, affecting primarily Purkinje cells in the cerebellar cortex. The mutant has been maintained in the Institut Pasteur, Paris,Cedex, France by Dr. Guenet J-L. The mutant mice imported to Experimental Animal Research Division, Life Science Tsukuba Research Center, RIKEN in 1997.
The mice were sib-mated for 6 generations in the conventional facility. Then, the mice were rederived by in vitro fertilization and embryo transfer into the SPF facility, followed by sib-mating for 18 generations (July, 2003).
Colony maintenance Coat color gene: A/A, ln/ln. The homozygous mutant mice exhibit neurological symptom characteristics to the cerebellar mutant, can not walk straight after weaning. The gene name Tambaleante comes from Spanish word
meaning a drunken person with awkward behavior. Histologically Purkinje cells in the cerebellar cortex degenerate rapidly after 2 months of age.
Both homozygous females and males can breed, but the females are poor breeders. The strain is maintained by sister-brother mating between heterozygous females and homozygous males.
Health Report No Data
Gene Details
Promoter No Data
1 Symbol Herc1
Symbol name hect (homologous to the E6-AP (UBE3A) carboxyl terminus) domain and RCC1 (CHC1)-like domain (RLD) 1
Chromosome 9
Common name No Data
Symbol description No Data
References Dev Biol. 1987 Dec;124(2):379-89.
J Neurosci. 1995 Mar;15(3 Pt 1):2040-56.

Cerebellar mutations affecting the postnatal survival of Purkinje cells in the mouse disclose a longitudinal pattern of differentially sensitive cells.
Cerebellar mutations affecting the postnatal survival of Purkinje cells in the mouse disclose a longitudinal pattern of differentially sensitive cells.
Cerebellar mutations affecting the postnatal survival of Purkinje cells in the mouse disclose a longitudinal pattern of differentially sensitive cells.
Research applications No Data
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The RECIPIENT of BIOLOGICAL RESOURCE shall obtain a prior written consent on use of it from the DEPOSITOR.
* The RIKEN BRC shall maintain, store, multiply and distribute the BIOLOGICAL RESOURCE in Japan only.
* Before any access to the biological resource, the Recipient will sign (as well as his/her administrative authority) the enclosed form to be sent to the Depositor (Institute Pasteur).
* Prior to applications for a patent, or intellectual property or other rights based on the results of research using the BIOLOGICAL RESOURCE, the recipient shall discuss such applications with the DEPOSITOR. Use of the BIOLOGICAL RESOURCE shall be a collaborative research with the DEPOSITOR. The DEPOSITOR requires to be co-owner for the inventions or other intellectual property generated by using the BIOLOGICAL RESOURCE.
Additional information
1 No Data
Depositor Guenet, Jean-Louis (Institut Pasteur) Guenet, Jean-Louis
Strain Status /
Availability
(Expected delivery)


Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months
BRC mice in Publications
Title Journal
(PMID)
Author
Progressive Purkinje cell degeneration in tambaleante mutant mice is a consequence of a missense mutation in HERC1 E3 ubiquitin ligase. PLoS Genet.5(12): e1000784 (2009).(20041218)
Mashimo T, Hadjebi O, Amair-Pinedo F, Tsurumi T, Langa F, Serikawa T, Sotelo C, Gu net JL, Rosa JL.

RBRC01029, RIS:DBA/2 and BALB/c (CXD2-N)

RBRC No. RBRC01029
Type Recombinant Inbred
Species Mus musculus
Strain name RIS:DBA/2 and BALB/c (CXD2-N)
Former Common name No Data
H-2 Haplotype No Data
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain description No Data
Health Report
Gene Details
Promoter No Data
1 Symbol No Data
Symbol name No Data
Chromosome No Data
Common name No Data
Symbol description No Data
References No Data

Research applications No Data
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
In publishing the research results to be obtained by use of the BIOLOGICAL RESOURCE, an acknowledgment to the DEPOSITOR is requested.
Additional information
1 No Data
Depositor Guenet, Jean-Louis (Institut Pasteur) Guenet, Jean-Louis
Strain Status /
Availability
(Expected delivery)


Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months