RBRC03328, B6.129-Ttll5<tm1Seto>/SetoRbrc

RBRC No. RBRC03328
Type Targeted MutationCartagena
Species Mus musculus
Strain name B6.129-Ttll5<tm1Seto>/SetoRbrc
Former Common name TL5 KO
H-2 Haplotype No Data
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain development Developed by Koji Ikegami and Mitsutoshi Setou, Mitsubishi Kagaku Institute of Life Sciences. 129 derived ES cells were used. The mice were crossed to C57BL/6J.
Strain description Ttll5 (TL5) gene knockout mice. Exon 13 was replaced with neo cassette. A region including glutamine acid necessary for activity was deleted (presumably, deficient activity of the enzymes, but not null). Initiation codon is in exon 2. Expression pattern : Not examined.
Colony maintenance Heterozygote x Wild-type [C57BL/6JJcl]
Health Report
Gene Details
Promoter No Data
1 Symbol Ttll5
Symbol name tubulin tyrosine ligase-like family, member 5
Chromosome 12
Common name No Data
Symbol description No Data
Promoter herpes simplex virus thymidine kinase promoter (HSV tk promoter)
2 Symbol neo
Symbol name neomycin resistance gene (E. coli)
Chromosome 12
Common name neo; neomycin;
Symbol description No Data
References No Data

Research applications Cell Biology Research
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The BIOLOGICAL RESOURCE shall be used only for academic research purposes by
a non-profit organization.
The RECIPIENT of a non-profit organization must prior contact RIKEN BRC and
negotiate with Mitsubishi Chemical Corporation to use the BIOLOGICAL
RESOURCE for purposes of other than academic research.
In publishing the research results to be obtained by use of the BIOLOGICAL
RESOURCE in relevant journals and meetings, the RECIPIENT must stipulate the
source of the BIOLOGICAL RESOURCE and an acknowledgment to Mitsubishi
Chemical Corporation.
The RECIPIENT agrees that RIKEN BRC informs annually to Mitsubishi Chemical
Corporation of RECIPIENT organization, RECIPIENT name, the specific research
purpose and the date of distribution.
Additional information
1 No Data
2 Genotyping protocol <PCR>
Depositor Setou, Mitsutoshi (Mitsubishi Kagaku Institute of Life Sciences) Setou, Mitsutoshi
Strain Status /
Availability
(Expected delivery)


Sperm
Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months

RBRC03329, B6;129-Ttll7<tm1Seto>/SetoRbrc

RBRC No. RBRC03329
Type Targeted MutationCartagena
Species Mus musculus
Strain name B6;129-Ttll7<tm1Seto>/SetoRbrc
Former Common name TL7 KO
H-2 Haplotype No Data
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain development Developed by Koji Ikegami and Mitsutoshi Setou, Mitsubishi Kagaku Institute of Life Sciences. 129 derived ES cells were used. The mice were crossed to C57BL/6J.
Strain description Ttll7 (TL7) gene knockout mice. Exons 2 and 3 were replaced with neo cassette. Exons 2 and 3 include initiation codons. ATGs were removed by homologous recombination. Null type mutant. Homozygous mutant mice show no obvious abnormality.
Colony maintenance Heterozygote x Wild-type [C57BL/6JJcl]
Health Report
Gene Details
Promoter No Data
1 Symbol neo
Symbol name neomycin resistance gene (E. coli)
Chromosome 3
Common name neo; neomycin;
Symbol description No Data
2 Symbol Ttll7
Symbol name tubulin tyrosine ligase-like family, member 7
Chromosome 3
Common name No Data
Symbol description No Data
References No Data

Research applications No Data
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The BIOLOGICAL RESOURCE shall be used only for academic research purposes by
a non-profit organization.
The RECIPIENT of a non-profit organization must prior contact RIKEN BRC and
negotiate with Mitsubishi Chemical Corporation to use the BIOLOGICAL
RESOURCE for purposes of other than academic research.
In publishing the research results to be obtained by use of the BIOLOGICAL
RESOURCE in relevant journals and meetings, the RECIPIENT must stipulate the
source of the BIOLOGICAL RESOURCE and an acknowledgment to Mitsubishi
Chemical Corporation.
The RECIPIENT agrees that RIKEN BRC informs annually to Mitsubishi Chemical
Corporation of RECIPIENT organization, RECIPIENT name, the specific research
purpose and the date of distribution.
Additional information
1 No Data
2 Genotyping protocol <PCR>
Depositor Setou, Mitsutoshi (Mitsubishi Kagaku Institute of Life Sciences) Setou, Mitsutoshi
Strain Status /
Availability
(Expected delivery)


Preparing for distribution
Preparing for distribution
(Please note that it may take more than 6 months to make arrangements to distribute.)

Sperm
Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months

RBRC03330, FB1 KO

RBRC No. RBRC03330
Type Targeted MutationCartagena
Species Mus musculus
Strain name FB1 KO
Former Common name No Data
H-2 Haplotype No Data
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain description No Data
Health Report No Data
Gene Details
Promoter No Data
1 Symbol neo
Symbol name neomycin resistance gene (E. coli)
Chromosome 11
Common name neo; neomycin;
Symbol description No Data
2 Symbol Fbxl20
Symbol name F-box and leucine-rich repeat protein 20
Chromosome 11
Common name No Data
Symbol description No Data
References Cell. 2007 Sep 7;130(5):943-57.

SCRAPPER-Dependent Ubiquitination of Active Zone Protein RIM1 Regulates Synaptic Vesicle Release.
Research applications No Data
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The BIOLOGICAL RESOURCE shall be used only for academic research purposes by
a non-profit organization.
The RECIPIENT of a non-profit organization must prior contact RIKEN BRC and
negotiate with Mitsubishi Chemical Corporation to use the BIOLOGICAL
RESOURCE for purposes of other than academic research.
In publishing the research results to be obtained by use of the BIOLOGICAL
RESOURCE in relevant journals and meetings, the RECIPIENT must stipulate the
source of the BIOLOGICAL RESOURCE and an acknowledgment to Mitsubishi
Chemical Corporation.
The RECIPIENT agrees that RIKEN BRC informs annually to Mitsubishi Chemical
Corporation of RECIPIENT organization, RECIPIENT name, the specific research
purpose and the date of distribution.
Additional information
1 No Data
Depositor Setou, Mitsutoshi (Mitsubishi Kagaku Institute of Life Sciences) Setou, Mitsutoshi
Strain Status /
Availability
(Expected delivery)


Preparing for distribution
Preparing for distribution
(Please note that it may take more than 6 months to make arrangements to distribute.)

Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

RBRC03331, UBL3 KO

RBRC No. RBRC03331
Type Targeted MutationCartagena
Species Mus musculus
Strain name UBL3 KO
Former Common name No Data
H-2 Haplotype No Data
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain description No Data
Health Report No Data
Gene Details
Promoter No Data
1 Symbol neo
Symbol name neomycin resistance gene (E. coli)
Chromosome 5
Common name neo; neomycin;
Symbol description No Data
2 Symbol Ubl3
Symbol name ubiquitin-like 3
Chromosome 5
Common name No Data
Symbol description No Data
References No Data

Research applications Cell Biology Research
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The BIOLOGICAL RESOURCE shall be used only for academic research purposes by
a non-profit organization.
The RECIPIENT of a non-profit organization must prior contact RIKEN BRC and
negotiate with Mitsubishi Chemical Corporation to use the BIOLOGICAL
RESOURCE for purposes of other than academic research.
In publishing the research results to be obtained by use of the BIOLOGICAL
RESOURCE in relevant journals and meetings, the RECIPIENT must stipulate the
source of the BIOLOGICAL RESOURCE and an acknowledgment to Mitsubishi
Chemical Corporation.
The RECIPIENT agrees that RIKEN BRC informs annually to Mitsubishi Chemical
Corporation of RECIPIENT organization, RECIPIENT name, the specific research
purpose and the date of distribution.
Additional information
1 No Data
Depositor Setou, Mitsutoshi (Mitsubishi Kagaku Institute of Life Sciences) Setou, Mitsutoshi
Strain Status /
Availability
(Expected delivery)


Preparing for distribution
Preparing for distribution
(Please note that it may take more than 6 months to make arrangements to distribute.)

Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

RBRC03332, C57BL/6-Ttll9<tm1Seto>/SetoRbrc

RBRC No. RBRC03332
Type Targeted MutationCartagena
Species Mus musculus
Strain name C57BL/6-Ttll9<tm1Seto>/SetoRbrc
Former Common name TL9 KO
H-2 Haplotype No Data
Background strain C57BL/6JJcl
Appearance
1 Appearance No Data
Genotype No Data
Strain development Developed by Koji Ikegami and Mitsutoshi Setou, Mitsubishi Kagaku Institute of Life Sciences. C57BL/6N derived ES cells were used. The mice were crossed to C57BL/6.
Strain description Ttll9 (TL9) gene knockout mice. Exons 4 and 5 were replaced with neo cassette. A region including an initiation site of TTL domain was removed. Initiation codon is in exon 1. Null type mutant. Homozygous mutant male mice are infertile.
Colony maintenance Heterozygote x Wild-type [C57BL/6JJcl]
Health Report No Data
Gene Details
Promoter No Data
1 Symbol neo
Symbol name neomycin resistance gene (E. coli)
Chromosome 2
Common name neo; neomycin;
Symbol description No Data
2 Symbol Ttll9
Symbol name tubulin tyrosine ligase-like family, member 9
Chromosome 2
Common name No Data
Symbol description No Data
References No Data

Research applications No Data
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The BIOLOGICAL RESOURCE shall be used only for academic research purposes by
a non-profit organization.
The RECIPIENT of a non-profit organization must prior contact RIKEN BRC and
negotiate with Mitsubishi Chemical Corporation to use the BIOLOGICAL
RESOURCE for purposes of other than academic research.
In publishing the research results to be obtained by use of the BIOLOGICAL
RESOURCE in relevant journals and meetings, the RECIPIENT must stipulate the
source of the BIOLOGICAL RESOURCE and an acknowledgment to Mitsubishi
Chemical Corporation.
The RECIPIENT agrees that RIKEN BRC informs annually to Mitsubishi Chemical
Corporation of RECIPIENT organization, RECIPIENT name, the specific research
purpose and the date of distribution.
Additional information
1 No Data
Depositor Setou, Mitsutoshi (Mitsubishi Kagaku Institute of Life Sciences) Setou, Mitsutoshi
Strain Status /
Availability
(Expected delivery)


Preparing for distribution
Preparing for distribution
(Please note that it may take more than 6 months to make arrangements to distribute.)

Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

RBRC03333, FBF-1-22 Tg

RBRC No. RBRC03333
Type TransgeneCartagena
Species Mus musculus
Strain name FBF-1-22 Tg
Former Common name No Data
H-2 Haplotype No Data
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain description No Data
Health Report No Data
Gene Details
Promoter No Data
1 Symbol FB1
Symbol name No Data
Chromosome No Data
Common name No Data
Symbol description No Data
Promoter mouse Camk2a promoter
2 Symbol EGFP
Symbol name Enhanced Green Fluorescent Protein, F64L and S65T (Jellyfish)
Chromosome No Data
Common name No Data
Symbol description No Data
References Cell. 2007 Sep 7;130(5):943-57.

SCRAPPER-Dependent Ubiquitination of Active Zone Protein RIM1 Regulates Synaptic Vesicle Release.
Research applications Fluorescent Proteins/lacZ System,
Genetics Research
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The BIOLOGICAL RESOURCE shall be used only for academic research purposes by
a non-profit organization.
The RECIPIENT of a non-profit organization must prior contact RIKEN BRC and
negotiate with Mitsubishi Chemical Corporation to use the BIOLOGICAL
RESOURCE for purposes of other than academic research.
In publishing the research results to be obtained by use of the BIOLOGICAL
RESOURCE in relevant journals and meetings, the RECIPIENT must stipulate the
source of the BIOLOGICAL RESOURCE and an acknowledgment to Mitsubishi
Chemical Corporation.
The RECIPIENT agrees that RIKEN BRC informs annually to Mitsubishi Chemical
Corporation of RECIPIENT organization, RECIPIENT name, the specific research
purpose and the date of distribution.
Additional information
1 No Data
Depositor Setou, Mitsutoshi (Mitsubishi Kagaku Institute of Life Sciences) Setou, Mitsutoshi
Strain Status /
Availability
(Expected delivery)


Preparing for distribution
Preparing for distribution
(Please note that it may take more than 6 months to make arrangements to distribute.)

Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

RBRC03334, FBF-1-26 Tg

RBRC No. RBRC03334
Type TransgeneCartagena
Species Mus musculus
Strain name FBF-1-26 Tg
Former Common name No Data
H-2 Haplotype No Data
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain description No Data
Health Report No Data
Gene Details
Promoter No Data
1 Symbol Mir130a
Symbol name microRNA 130a
Chromosome UN
Common name No Data
Symbol description No Data
Promoter mouse Camk2a promoter
2 Symbol EGFP
Symbol name Enhanced Green Fluorescent Protein, F64L and S65T (Jellyfish)
Chromosome No Data
Common name No Data
Symbol description No Data
References Cell. 2007 Sep 7;130(5):943-57.

SCRAPPER-Dependent Ubiquitination of Active Zone Protein RIM1 Regulates Synaptic Vesicle Release.
Research applications Fluorescent Proteins/lacZ System,
Genetics Research
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The BIOLOGICAL RESOURCE shall be used only for academic research purposes by
a non-profit organization.
The RECIPIENT of a non-profit organization must prior contact RIKEN BRC and
negotiate with Mitsubishi Chemical Corporation to use the BIOLOGICAL
RESOURCE for purposes of other than academic research.
In publishing the research results to be obtained by use of the BIOLOGICAL
RESOURCE in relevant journals and meetings, the RECIPIENT must stipulate the
source of the BIOLOGICAL RESOURCE and an acknowledgment to Mitsubishi
Chemical Corporation.
The RECIPIENT agrees that RIKEN BRC informs annually to Mitsubishi Chemical
Corporation of RECIPIENT organization, RECIPIENT name, the specific research
purpose and the date of distribution.
Additional information
1 GFP Transfer License (Japanese / English)
Please fill in the Schedule A, and submit two signed copies to us together with two signed copies of RIKEN BRC’s MTA. Please also read Schedule B.
Depositor Setou, Mitsutoshi (Mitsubishi Kagaku Institute of Life Sciences) Setou, Mitsutoshi
Strain Status /
Availability
(Expected delivery)


Preparing for distribution
Preparing for distribution
(Please note that it may take more than 6 months to make arrangements to distribute.)

Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

RBRC03335, FBF-1-31 Tg

RBRC No. RBRC03335
Type TransgeneCartagena
Species Mus musculus
Strain name FBF-1-31 Tg
Former Common name No Data
H-2 Haplotype No Data
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain description No Data
Health Report No Data
Gene Details
Promoter No Data
1 Symbol Mir130a
Symbol name microRNA 130a
Chromosome UN
Common name No Data
Symbol description No Data
Promoter mouse Camk2a promoter
2 Symbol EGFP
Symbol name Enhanced Green Fluorescent Protein, F64L and S65T (Jellyfish)
Chromosome No Data
Common name No Data
Symbol description No Data
References Cell. 2007 Sep 7;130(5):943-57.

SCRAPPER-Dependent Ubiquitination of Active Zone Protein RIM1 Regulates Synaptic Vesicle Release.
Research applications Fluorescent Proteins/lacZ System,
Genetics Research
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The BIOLOGICAL RESOURCE shall be used only for academic research purposes by
a non-profit organization.
The RECIPIENT of a non-profit organization must prior contact RIKEN BRC and
negotiate with Mitsubishi Chemical Corporation to use the BIOLOGICAL
RESOURCE for purposes of other than academic research.
In publishing the research results to be obtained by use of the BIOLOGICAL
RESOURCE in relevant journals and meetings, the RECIPIENT must stipulate the
source of the BIOLOGICAL RESOURCE and an acknowledgment to Mitsubishi
Chemical Corporation.
The RECIPIENT agrees that RIKEN BRC informs annually to Mitsubishi Chemical
Corporation of RECIPIENT organization, RECIPIENT name, the specific research
purpose and the date of distribution.
Additional information
1 GFP Transfer License (Japanese / English)
Please fill in the Schedule A, and submit two signed copies to us together with two signed copies of RIKEN BRC’s MTA. Please also read Schedule B.
Depositor Setou, Mitsutoshi (Mitsubishi Kagaku Institute of Life Sciences) Setou, Mitsutoshi
Strain Status /
Availability
(Expected delivery)


Preparing for distribution
Preparing for distribution
(Please note that it may take more than 6 months to make arrangements to distribute.)

Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

RBRC03336, FBF-2-5 Tg

RBRC No. RBRC03336
Type TransgeneCartagena
Species Mus musculus
Strain name FBF-2-5 Tg
Former Common name No Data
H-2 Haplotype No Data
Background strain No Data
Appearance
1 Appearance No Data
Genotype No Data
Strain description No Data
Health Report No Data
Gene Details
Promoter No Data
1 Symbol Mir130a
Symbol name microRNA 130a
Chromosome UN
Common name No Data
Symbol description No Data
Promoter mouse Camk2a promoter
2 Symbol EGFP
Symbol name Enhanced Green Fluorescent Protein, F64L and S65T (Jellyfish)
Chromosome UN
Common name No Data
Symbol description No Data
References Cell. 2007 Sep 7;130(5):943-57.

SCRAPPER-Dependent Ubiquitination of Active Zone Protein RIM1 Regulates Synaptic Vesicle Release.
Research applications Fluorescent Proteins/lacZ System,
Genetics Research
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The BIOLOGICAL RESOURCE shall be used only for academic research purposes by
a non-profit organization.
The RECIPIENT of a non-profit organization must prior contact RIKEN BRC and
negotiate with Mitsubishi Chemical Corporation to use the BIOLOGICAL
RESOURCE for purposes of other than academic research.
In publishing the research results to be obtained by use of the BIOLOGICAL
RESOURCE in relevant journals and meetings, the RECIPIENT must stipulate the
source of the BIOLOGICAL RESOURCE and an acknowledgment to Mitsubishi
Chemical Corporation.
The RECIPIENT agrees that RIKEN BRC informs annually to Mitsubishi Chemical
Corporation of RECIPIENT organization, RECIPIENT name, the specific research
purpose and the date of distribution.
Additional information
1 GFP Transfer License (Japanese / English)
Please fill in the Schedule A, and submit two signed copies to us together with two signed copies of RIKEN BRC’s MTA. Please also read Schedule B.
Depositor Setou, Mitsutoshi (Mitsubishi Kagaku Institute of Life Sciences) Setou, Mitsutoshi
Strain Status /
Availability
(Expected delivery)


Preparing for distribution
Preparing for distribution
(Please note that it may take more than 6 months to make arrangements to distribute.)

Frozen
Cryopreserved embryos : Within 1 month
Recovered litters from cryopreserved embryos : 2-4 months

RBRC03337, C57BL/6N-Ttll11<tm1Seto>/SetoRbrc

RBRC No. RBRC03337
Type Targeted MutationCartagena
Species Mus musculus
Strain name C57BL/6N-Ttll11<tm1Seto>/SetoRbrc
Former Common name TTLL11 KO
H-2 Haplotype No Data
Background strain C57BL/6NJcl
Appearance
1 Appearance No Data
Genotype No Data
Strain development Developed by Koji Ikegami and Mitsutoshi Setou, Mitsubishi Kagaku Institute of Life Sciences. C57BL/6N derived ES cells (RENKA) were used. The mice were crossed to C57BL/6N.
Strain description Ttll11 (TL11) gene knockout mice. Exon 4 was replaced with neo cassette. Initiation codon is in exon 1, therefore exons 1 to 4 were transcribed and translated. Exon 4 codes most of TTL domain (70%). TTL was disrupted by homologous recombination. Expression : Not examined.
Colony maintenance Heterozygote x Wild-type [C57BL/6NJcl]
Health Report
Gene Details
Promoter No Data
1 Symbol neo
Symbol name neomycin resistance gene (E. coli)
Chromosome 2
Common name neo; neomycin;
Symbol description No Data
2 Symbol Ttll11
Symbol name tubulin tyrosine ligase-like family, member 11
Chromosome 2
Common name No Data
Symbol description No Data
References No Data

Research applications No Data
Specific Term and Conditions The following terms and conditions will be requested by the DEPOSITOR.
The BIOLOGICAL RESOURCE shall be used only for academic research purposes by
a non-profit organization.
The RECIPIENT of a non-profit organization must prior contact RIKEN BRC and
negotiate with Mitsubishi Chemical Corporation to use the BIOLOGICAL
RESOURCE for purposes of other than academic research.
In publishing the research results to be obtained by use of the BIOLOGICAL
RESOURCE in relevant journals and meetings, the RECIPIENT must stipulate the
source of the BIOLOGICAL RESOURCE and an acknowledgment to Mitsubishi
Chemical Corporation.
The RECIPIENT agrees that RIKEN BRC informs annually to Mitsubishi Chemical
Corporation of RECIPIENT organization, RECIPIENT name, the specific research
purpose and the date of distribution.
Additional information
1 No Data
2 Genotyping protocol <PCR>
Depositor Setou, Mitsutoshi (Mitsubishi Kagaku Institute of Life Sciences) Setou, Mitsutoshi
Strain Status /
Availability
(Expected delivery)


Sperm
Cryopreserved sperm : Within 1 month
Recovered litters from cryopreserved sperm : 2-4 months